The traJ 5' UTR is a cis acting RNA element which is involved in regulating plasmid transfer in bacteria.
In
conjugating bacteria the FinOP system regulates the transfer of
F-like plasmids. The
FinP gene encodes an
antisense RNA
Antisense RNA (asRNA), also referred to as antisense transcript, natural antisense transcript (NAT) or antisense oligonucleotide, is a single stranded RNA that is complementary to a protein coding messenger RNA (mRNA) with which it hybridizes, and ...
product that is complementary to part of the
5' UTR
The 5′ untranslated region (also known as 5′ UTR, leader sequence, transcript leader, or leader RNA) is the region of a messenger RNA (mRNA) that is directly upstream from the initiation codon. This region is important for the regulation of ...
of the traJ mRNA.
The traJ gene encodes a protein required for transcription from the major transfer
promoter, pY. The FinO protein is essential for effective repression, acting by binding to FinP and protecting it from
RNase
Ribonuclease (commonly abbreviated RNase) is a type of nuclease that catalyzes the degradation of RNA into smaller components. Ribonucleases can be divided into endoribonucleases and exoribonucleases, and comprise several sub-classes within the ...
E degradation.
References
External links
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Cis-regulatory RNA elements
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