Tombus virus defective interfering (DI) RNA region 3 is an important
cis-regulatory region identified in the
3' UTR
In molecular genetics, the three prime untranslated region (3′-UTR) is the section of messenger RNA (mRNA) that immediately follows the translation termination codon. The 3′-UTR often contains regulatory regions that post-transcriptionally ...
of ''
Tombusvirus
''Tombusvirus'' is a genus of viruses, in the family '' Tombusviridae''. Plants serve as natural hosts. There are 17 species in this genus. Symptoms associated with this genus include mosaic. The name of the genus comes from ''Tomato bushy stunt ...
'' defective interfering particles (DI).
Defective interfering RNAs are small sub-viral
replicons which are non-coding deletion mutants of the virus that maintain cis-acting RNA elements necessary for
replication of the host virus.
This conserved region of the 3'UTR has been found to enhance DI RNA accumulation by approximately 10-fold as well as mediating
viral replication
Viral replication is the formation of biological viruses during the infection process in the target host cells. Viruses must first get into the cell before viral replication can occur. Through the generation of abundant copies of its genome an ...
.
See also
*
Infectious bronchitis virus D-RNA
*
Red clover necrotic mosaic virus translation enhancer elements
References
External links
*
Cis-regulatory RNA elements
Tombusviridae
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