Tizoxanide, also known as desacetyl-nitazoxanide, is a
thiazolide and an
antiparasitic agent
Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases, such as those caused by helminths, amoeba, ectoparasites, parasitic fungi, and protozoa, among others. Antiparasitics target the parasitic agent ...
that occurs as a
metabolite
In biochemistry, a metabolite is an intermediate or end product of metabolism.
The term is usually used for small molecules. Metabolites have various functions, including fuel, structure, signaling, stimulatory and inhibitory effects on enzymes, c ...
of
nitazoxanide
Nitazoxanide, sold under the brand name Alinia among others, is a broad-spectrum antiparasitic and broad-spectrum antiviral medication that is used in medicine for the treatment of various helminthic, protozoal, and viral infections. It is ind ...
in humans through hydrolysis.
Tizoxanide may undergo further metabolism via conjugation into
tizoxanide glucuronide
Tizoxanide, also known as desacetyl-nitazoxanide, is a thiazolide and an antiparasitic agent that occurs as a metabolite of nitazoxanide
Nitazoxanide, sold under the brand name Alinia among others, is a broad-spectrum antiparasitic and broad-s ...
.
References
Nitrothiazoles
Salicylamides
Human drug metabolites
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