Timothy A Stewart (born 30 September 1952) is a molecular biologist. He graduated from the
University of Otago
, image_name = University of Otago Registry Building2.jpg
, image_size =
, caption = University clock tower
, motto = la, Sapere aude
, mottoeng = Dare to be wise
, established = 1869; 152 years ago
, type = Public research collegiate ...
(BScHons, PhD.)
Stewart was born in
Christchurch
Christchurch ( ; mi, Ōtautahi) is the largest city in the South Island of New Zealand and the seat of the Canterbury Region. Christchurch lies on the South Island's east coast, just north of Banks Peninsula on Pegasus Bay. The Avon Rive ...
, New Zealand. He was a pioneer in the technique of transferring recombinant genes to mice (
transgenic mice
A genetically modified mouse or genetically engineered mouse model (GEMM) is a mouse (''Mus musculus'') that has had its genome altered through the use of genetic engineering techniques. Genetically modified mice are commonly used for research or ...
) and in 1988 he and
Philip Leder
Philip Leder (November 19, 1934 – February 2, 2020) was an American geneticist.
Early life and education
Leder was born in Washington, D.C. and studied at Harvard University, graduating in 1956. In 1960, he graduated from Harvard Medical Sc ...
were granted a patent on a genetically engineered mammal. This "
oncomouse
The OncoMouse or Harvard mouse is a type of laboratory mouse (''Mus musculus'') that has been genetically modified using modifications designed by Philip Leder and Timothy A Stewart of Harvard University to carry a specific gene called an activ ...
" patent was the first to be issued covering a higher life form.
From 1984 to 2003 Stewart was a scientist at
Genentech where he developed the concept that the type I interferons might be a significant component in the initiation or progression of
type I diabetes
Type 1 diabetes (T1D), formerly known as juvenile diabetes, is an autoimmune disease that originates when cells that make insulin (beta cells) are destroyed by the immune system. Insulin is a hormone required for the cells to use blood sugar for ...
.
He has published 61 peer reviewed papers listed in
Scopus
Scopus is Elsevier's abstract and citation database launched in 2004. Scopus covers nearly 36,377 titles (22,794 active titles and 13,583 inactive titles) from approximately 11,678 publishers, of which 34,346 are peer-reviewed journals in top-l ...
; the most highly cited has 1013 citations to it,
and he has 31 papers with 34 citations or more.
References
1952 births
Living people
New Zealand biologists
University of Otago alumni
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