Timothy Eric McKnight is an American biologist. He has been a key developer of a cell transfecting method using vertically aligned
carbon nanofibers
Carbon nanofibers (CNFs), vapor grown carbon fibers (VGCFs), or vapor grown carbon nanofibers (VGCNFs) are cylindrical nanostructures with graphene layers arranged as stacked cone (geometry), cones, cups or plates. Carbon nanofibers with graphene ...
. Arrays of vertically aligned carbon nanofibers are modified with
DNA and pressed into cells and tissue. Surviving cells can express DNA that is delivered during the penetration event, even when the DNA is covalently bound to the penetrant nanofiber element. This gene delivery technique has been termed
Impalefection
Impalefection is a method of gene delivery using nanomaterials, such as carbon nanofibers, carbon nanotubes, nanowires. Needle-like nanostructures are synthesized perpendicular to the surface of a substrate. Plasmid DNA containing the gene, and ...
.
Selected publications
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21st-century American biologists
Living people
Year of birth missing (living people)
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