Tianqiao And Chrissy Chen Institute
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The Tianqiao and Chrissy Chen Institute (also referred to as the Chen Institute or TCCI) is a non-profit institute founded by husband and wife
Tianqiao Chen Chen Tianqiao (); born 1973) is a Chinese businessman and philanthropist. (published 01-25-20) (published 12-21-20) (published 05-23-20) His wealth is estimated at US$4 billion. Chen moved from Shanghai to Singapore in 2009 and then to the Bay A ...
and Chrissy Luo with the aim of supporting study into the
human brain The human brain is the central organ of the human nervous system, and with the spinal cord makes up the central nervous system. The brain consists of the cerebrum, the brainstem and the cerebellum. It controls most of the activities of the ...
. In 2016 the couple committed US$1 billion to support the institute’s work, which focuses on research in three core areas – brain discovery, brain treatment and brain development. Towards that end, the institute supports interdisciplinary research concerning
neuroscience Neuroscience is the scientific study of the nervous system (the brain, spinal cord, and peripheral nervous system), its functions and disorders. It is a multidisciplinary science that combines physiology, anatomy, molecular biology, development ...
, particularly research on brain mechanics,
perception Perception () is the organization, identification, and interpretation of sensory information in order to represent and understand the presented information or environment. All perception involves signals that go through the nervous system ...
,"Focus Vision Cornerstone Partnerships"
- Chen Institute
and the impact of perception on behavior and well-being."The Mysterious Case of the Missing Internet Billionaire"
- ''
Bloomberg Bloomberg may refer to: People * Daniel J. Bloomberg (1905–1984), audio engineer * Georgina Bloomberg (born 1983), professional equestrian * Michael Bloomberg (born 1942), American businessman and founder of Bloomberg L.P.; politician and ma ...
'' - Yoolim Lee - August 15, 2017


History


Background

The Chen Institute was founded by Chrissy and Tianqiao Chen, both philanthropists known for co-founding the
Chinese Chinese can refer to: * Something related to China * Chinese people, people of Chinese nationality, citizenship, and/or ethnicity **''Zhonghua minzu'', the supra-ethnic concept of the Chinese nation ** List of ethnic groups in China, people of va ...
conglomerate Shanda Group in 1999.Kerry Dolan, They decided to create the Chen Institute to fund various brain-related research initiatives and institutions,"Why Chinese billionaire Tianqiao Chen transitioned from investing in video games to CHS, neuroscience"
- ''Becker's Hospital Review'' - Alyssa Rage - August 17, 2017
citing a project by
Caltech The California Institute of Technology (branded as Caltech or CIT)The university itself only spells its short form as "Caltech"; the institution considers other spellings such a"Cal Tech" and "CalTech" incorrect. The institute is also occasional ...
scientist Richard Andersen as being particularly inspirational. Upon seeing Richard A Andersen's, who along with David J. Anderson directs part of T&C Chen Institute, mind-machine brain interface help a
quadriplegic Tetraplegia, also known as quadriplegia, is defined as the dysfunction or loss of motor and/or sensory function in the cervical area of the spinal cord. A loss of motor function can present as either weakness or paralysis leading to partial or t ...
use thoughts to control a robotic arm on television,"China’s Rising Philanthropy Presents the Next Big Brain Science Donor"
- ''
Inside Philanthropy ''Inside Philanthropy'' is a news website about large philanthropic foundations and wealthy donors, created by David Callahan David Callahan (born 1964/1965) is an American writer and editor. He is the founder and editor of ''Inside Philan ...
'' -Tate Williams - December 13, 2016
they flew from
Singapore Singapore (), officially the Republic of Singapore, is a sovereign island country and city-state in maritime Southeast Asia. It lies about one degree of latitude () north of the equator, off the southern tip of the Malay Peninsula, borde ...
to Caltech in
Pasadena, California Pasadena ( ) is a city in Los Angeles County, California, northeast of downtown Los Angeles. It is the most populous city and the primary cultural center of the San Gabriel Valley. Old Pasadena is the city's original commercial district. I ...
to meet Anderson in person. The couple subsequently set aside $1 billion to donate to related efforts on brain-related treatment, as well as research and development."Chinese Donors Step Up Giving to American Universities"
- ''
The Chronicle of Higher Education ''The Chronicle of Higher Education'' is a newspaper and website that presents news, information, and jobs for college and university faculty and student affairs professionals (staff members and administrators). A subscription is required to rea ...
'' - Mimi Leung - December 21, 2016
They then spent two years researching possible partners. In March 2017, the Tianqiao and Chrissy Chen Institute announced a plan to annually donate around $100 million each year. With the goal of "
assing Assing is a German surname. Notable people with the surname include: * David Assing (1787–1842), German physician and poet * Rosa Maria Assing, née Varnhagen (1783–1840), German writer ** Ottilie Assing (1819–1884), German writer ** Ludm ...
the ball to whoever is closest to the goal," new proposals from universities would be gauged for at least a year each, and after that point, money would be donated to scientists directly.


Caltech institute

In its first donation,Qian Tongxin, on December 8, 2016, it was announced that the Chen Institute was donating $115 million to fund the formation of the Tianqiao and Chrissy Chen Institute for Neuroscience at Caltech. The Chens stated that they selected Caltech as the first recipient because of the school's entrepreneurial and interdisciplinary approach to the field. The $115 million Caltech donation resulted in some controversy in Chinese academia, with arguments made that the donations would have been more beneficial to a Chinese university. Other academics defended the donation on the grounds that Chinese universities were often less transparent, noting that the Chens had previously withheld gifts to Chinese institutions when they refused to provide usage reports. The funds were set aside to establish the new institute's building and provide Caltech with continuous resources for neuroscience research, with direction of that research to be decided by the university. It was announced that th
Chen Neuroscience Research Building
would serve as the administrative center for the Tianqiao and Chrissy Chen Institute for Neuroscience,"Billionaire-Backed Brain Research Center Breaks Ground at Caltech"
- ''
Pasadena Now Pasadena ( ) is a city in Los Angeles County, California, northeast of downtown Los Angeles. It is the most populous city and the primary cultural center of the San Gabriel Valley. Old Pasadena is the city's original commercial district. ...
'' - Brandon Villalovos - December 6, 2017
and hous
seven interdisciplinary research centers
ref name="e"/> which together formed "the core of the Chen Institute." The university explained that the research complex would combine "biology, engineering, chemistry, physics, computer science and the social sciences to tackle brain function in an integrated, comprehensive way." In August 2017, it was announced that David J. Anderson would serve as director of the Tianqiao and Chrissy Chen Institute for Neuroscience. Also that month, plans for the new Caltech building were heard by the design commission of Pasadena. The groundbreaking of the Tianqiao and Chrissy Chen Neuroscience Research Building took place in December 2017. With construction beginning in January 2018, the opening occurred in January 2021.


Shanghai institute

In November 2017, the Tianqiao and Chrissy Chen Institute announced that $80 million would fund The Tianqiao and Chrissy Chen Institute (Shanghai). The nonprofit brain disease institute was formed as a partnership with Huashan Hospital in
Shanghai Shanghai (; , , Standard Mandarin pronunciation: ) is one of the four direct-administered municipalities of the People's Republic of China (PRC). The city is located on the southern estuary of the Yangtze River, with the Huangpu River flow ...
, which in turn is affiliated with
Fudan University Fudan University () is a national public research university in Shanghai, China. Fudan is a member of the C9 League, Project 985, Project 211, and the Double First Class University identified by the Ministry of Education of China. It is als ...
, and Zhou Liangfu Foundation. The institute announced a focus on international collaboration and brain disease research, with plans to study "
brain tumor A brain tumor occurs when abnormal cells form within the brain. There are two main types of tumors: malignant tumors and benign (non-cancerous) tumors. These can be further classified as primary tumors, which start within the brain, and seconda ...
s,
Alzheimer’s disease Alzheimer's disease (AD) is a neurodegenerative disease that usually starts slowly and progressively worsens. It is the cause of 60–70% of cases of dementia. The most common early symptom is difficulty in remembering recent events. As t ...
,
Parkinson’s disease Parkinson's disease (PD), or simply Parkinson's, is a long-term degenerative disorder of the central nervous system that mainly affects the motor system. The symptoms usually emerge slowly, and as the disease worsens, non-motor symptoms becom ...
, depression and other brain ailments." In June 2018, the institute announced that it was partnering with the
Shanghai Mental Health Center Shanghai Mental Health Center (), also known as Shanghai Psychological Consultative Center, is a psychiatric hospital in Shanghai with over 2100 beds. It's focusing on treating mental disorders. It was founded in 1935, as Puci Rehabilitation Hospit ...
to fund the study of mental illness.


Chen Frontier Lab for Brain Research

In October 2020, the Tianqiao and Chrissy Chen Institute opened its first
Chen Frontier Lab for Brain Research
at Huashan Hospital's Hongqiao Campus in Shanghai
The Chen Frontier Lab for Applied Neurotechnology
seeks to achieve accomplishments in four dimensions: scientific research, talent development, standards formulation and industry research. It has a particular focus on Brain-Machine Interface,
Sleep Sleep is a sedentary state of mind and body. It is characterized by altered consciousness, relatively inhibited sensory activity, reduced muscle activity and reduced interactions with surroundings. It is distinguished from wakefulness by a de ...
and Dreams, Cognitive Assessment, Diagnosis & Intervention and Digital Medicine. In July 2021, TCC
announced
that it had signed an agreement with
Shanghai Mental Health Center Shanghai Mental Health Center (), also known as Shanghai Psychological Consultative Center, is a psychiatric hospital in Shanghai with over 2100 beds. It's focusing on treating mental disorders. It was founded in 1935, as Puci Rehabilitation Hospit ...
to open a second Frontier focused on
artificial intelligence Artificial intelligence (AI) is intelligence—perceiving, synthesizing, and inferring information—demonstrated by machines, as opposed to intelligence displayed by animals and humans. Example tasks in which this is done include speech re ...
and
mental health Mental health encompasses emotional, psychological, and social well-being, influencing cognition, perception, and behavior. It likewise determines how an individual handles stress, interpersonal relationships, and decision-making. Mental health ...
. At the ceremony, Professo
Xu Yifeng
Director of Shanghai Mental Health Center, touched on the Center’s concerted exploration of
brain disease Central nervous system diseases, also known as central nervous system disorders, are a group of neurological disorders that affect the structure or function of the brain or spinal cord, which collectively form the central nervous system (CNS). Th ...
and its treatment and preventions for
mental disorders A mental disorder, also referred to as a mental illness or psychiatric disorder, is a behavioral or mental pattern that causes significant distress or impairment of personal functioning. Such features may be persistent, relapsing and remitti ...
.


Areas of focus and mission

The Tianqiao and Chrissy Chen InstituteJeevan Vasagar, Kerry Dolan, is interested in three core areas: brain discovery, brain treatment, and brain development. In particular, the institute aims to support
fundamental Fundamental may refer to: * Foundation of reality * Fundamental frequency, as in music or phonetics, often referred to as simply a "fundamental" * Fundamentalism, the belief in, and usually the strict adherence to, the simple or "fundamental" idea ...
brain research with a focus on "understanding the sensation-perception mechanisms and related systems of memory, attention, learning and expectations." The institute's stated goal is to fund universities and institutions in forms such as endowed institutes,"Design Commission Hears Details of Major New Caltech Research Center"
- ''
Pasadena Now Pasadena ( ) is a city in Los Angeles County, California, northeast of downtown Los Angeles. It is the most populous city and the primary cultural center of the San Gabriel Valley. Old Pasadena is the city's original commercial district. ...
'' - August 7, 2017
grants for researchers, professorships, or "topic-specific programs" for scientists. Co-founder Tianqiao Chen has explained that "the key of
he institute's He or HE may refer to: Language * He (pronoun), an English pronoun * He (kana), the romanization of the Japanese kana へ * He (letter), the fifth letter of many Semitic alphabets * He (Cyrillic), a letter of the Cyrillic script called ''He'' in ...
philanthropy vision" is furthering understanding of perception, arguing that such research would help people master negative emotions. According to Chen, “for thousands of years, we improved our happiness through changing the physical world. We now have to solve this problem by exploring inward.


Programs and institutions

*The Tianqiao and Chrissy Chen Institute for Neuroscience at Caltech *The T&C Chen Brain-Machine Interface Center *The T&C Chen Center for Social and Decision Neuroscience *The T&C Chen Center for Systems Neuroscience *The Center for Molecular and Cellular Neuroscience *The Chen Center for Data Science and Artificial Intelligence *The Caltech Brain Imaging Center *The Tianqiao and Chrissy Chen Institute (Shanghai)


Research and recognition

Since its inception, researchers at the Tianqiao and Chrissy Chen Institute at Caltech hav
published research
on topics such as aiding paralyzed patients feel sensation, the neural processes associated with fear, deciphering how the brain manages thirst, the mechanisms behind memory recollection, the neural codes for body movements, and others. A number of Tianqiao and Chrissy Chen Institute researchers have received awards for their work. Institute researchers at Huashan Hospital, for example, received two
National Science and Technology Award National may refer to: Common uses * Nation or country ** Nationality – a ''national'' is a person who is subject to a nation, regardless of whether the person has full rights as a citizen Places in the United States * National, Maryland, ce ...
s in 2017 for their work on “Basic and Clinical Innovation Methods for Cerebral Fluid Through Surgery.”"TCCI Researchers Win Two National Science & Technology Progress Awards"
- Chen Institute - January 9, 2018


Documentary

The institute commissioned the documentary
Minds Wide Open
'' which aired on the
Discovery Channel Discovery Channel (known as The Discovery Channel from 1985 to 1995, and often referred to as simply Discovery) is an American cable channel owned by Warner Bros. Discovery, a publicly traded company run by CEO David Zaslav. , Discovery Channe ...
in 2018. An hour long, according to ''
Barron's Barron's or Barrons may refer to: *Barron's Educational Series, a publisher of books, as well as college entrance exam preparation classes and materials, now an imprint of Kaplan Test Prep ** B.E.S. Publishing, the former owner of Barron's * ''Barr ...
'' it "builds a case for why scientists need to focus on very basic questions of how the brain works and gives special attention to several young scientists who are on the verge of breakthroughs."''Barron's''
accessed November 13, 2019
The film won Gold Awards in the 2018
Cannes Cannes ( , , ; oc, Canas) is a city located on the French Riviera. It is a communes of France, commune located in the Alpes-Maritimes departments of France, department, and host city of the annual Cannes Film Festival, Midem, and Cannes Lions I ...
Corporate Media & TV Award film categories of medical, educational, and science and technology."Minds Wide Open Documentary Showcases a Hopeful Future for Brain Science"
- Chen Institute - 2018


References


External links

* {{official website, http://www.cheninstitute.org Neuroscience research centers in California California Institute of Technology buildings and structures Non-profit organizations based in California