Tiacumicins are a family of
macrolide
The Macrolides are a class of natural products that consist of a large macrocyclic lactone ring to which one or more deoxy sugars, usually cladinose and desosamine, may be attached. The lactone rings are usually 14-, 15-, or 16-membered. Ma ...
antibiotics derived from ''
Dactylosporangium aurantiacum'' subspecies hamdenesis subspecies Nov. The tiacumicin family of antibiotics has substantial overlap with the
clostomicin family.
Six 18-membered antibiotics in the tiacumicin family have been identified: tiacumicins A through F.
Currently, only one of these, tiacumicin B (also lipiarmycin, clostomicin B
1) is commercially available, under the generic name
fidaxomicin
Fidaxomicin, sold under the brand name Dificid among others, is the first member of a class of narrow spectrum macrocyclic antibiotic drugs called tiacumicins. It is a fermentation product obtained from the actinomycete '' Dactylosporangium aura ...
.
References
{{antibiotic-stub
Macrolide antibiotics