Thomas J. Silhavy is the Warner-Lambert Parke-Davis Professor of molecular biology at Princeton University. Silhavy is a bacterial geneticist who has made fundamental contributions to several different research fields. He is best known for his work on protein secretion, membrane biogenesis, and

signal transduction Signal transduction is the process by which a chemical or physical signal is transmitted through a cell as a series of molecular events, most commonly protein phosphorylation catalyzed by protein kinases, which ultimately results in a cellula ...

. Using '' Escherichia coli'' as a model system, his lab was the first to isolate signal sequence mutations, identify a component of cellular protein secretion machinery, discover an integral membrane component of the outer membrane assembly machinery, and to identify and characterize a two-component regulatory system. Current work in his lab is focused on the mechanisms of outer membrane biogenesis and the regulatory systems that sense and respond to envelope stress and trigger the developmental pathway that allows cells to survive starvation. He is the author of more than 200 research articles and three books. Silhavy was elected to the

National Academy of Sciences The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the Nati ...

in 2005.

Honors

*2016 American Society for Microbiology Lifetime Achievement Award *2011–2021 Editor-in-Chief, '' Journal of Bacteriology'' *2008

Genetics Society of America The Genetics Society of America (GSA) is a scholarly membership society of more than 5,500 genetics researchers and educators, established in 1931. The Society was formed from the reorganization of the Joint Genetics Sections of the American Soc ...

Novitski Prize *2008 Associate Member of the European Molecular Biology Organization (EMBO) *2005 Member of American Academy of Arts and Sciences *2005 Member of the

*2002 Graduate Microbiology Teaching Award from American Society for Microbiology retrieved 2010-08-16

Trainees

Scott D. Emr Scott D. Emr (born February 8, 1954) is an American cell biologist and the founding and current Director of the Weill Institute for Cell and Molecular Biology at Cornell University, where he is also a Frank H.T. Rhodes Class of 1956 Professor ...

* Michael N. Hall

External links

Profile of Silhavy

References

{{DEFAULTSORT:Silhavy, Thomas Living people American molecular biologists Princeton University faculty Members of the United States National Academy of Sciences American microbiologists Harvard University alumni 1948 births