Thomas C. Peebles
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Thomas Chalmers Peebles (June 5, 1921 – July 8, 2010) was an American
physician A physician (American English), medical practitioner (Commonwealth English), medical doctor, or simply doctor, is a health professional who practices medicine, which is concerned with promoting, maintaining or restoring health through th ...
who made multiple discoveries in the field of medicine, including being the first to isolate the
measles Measles is a highly contagious infectious disease caused by measles virus. Symptoms usually develop 10–12 days after exposure to an infected person and last 7–10 days. Initial symptoms typically include fever, often greater than , cough, ...
virus A virus is a submicroscopic infectious agent that replicates only inside the living cells of an organism. Viruses infect all life forms, from animals and plants to microorganisms, including bacteria and archaea. Since Dmitri Ivanovsky's 1 ...
. Peebles also did research that led to the development of fluoridated vitamins and did research that showed that
tetanus vaccine Tetanus vaccine, also known as tetanus toxoid (TT), is a toxoid vaccine used to prevent tetanus. During childhood, five doses are recommended, with a sixth given during adolescence. After three doses, almost everyone is initially immune, but a ...
could be given once every 10 years, rather than annually as had been the widespread practice. Peebles was born on June 5, 1921, in
Newton, Massachusetts Newton is a city in Middlesex County, Massachusetts, United States. It is approximately west of downtown Boston. Newton resembles a patchwork of thirteen villages, without a city center. According to the 2020 U.S. Census, the population of Ne ...
, and graduated from
Harvard University Harvard University is a private Ivy League research university in Cambridge, Massachusetts. Founded in 1636 as Harvard College and named for its first benefactor, the Puritan clergyman John Harvard, it is the oldest institution of higher le ...
in 1942 with a major in
French language French ( or ) is a Romance language of the Indo-European family. It descended from the Vulgar Latin of the Roman Empire, as did all Romance languages. French evolved from Gallo-Romance, the Latin spoken in Gaul, and more specifically in Nor ...
. He enlisted in the
United States Navy The United States Navy (USN) is the maritime service branch of the United States Armed Forces and one of the eight uniformed services of the United States. It is the largest and most powerful navy in the world, with the estimated tonnage ...
and served as a bomber pilot in the Pacific Theater of Operations, earning the Distinguished Flying Cross. He had been recruited by
KLM KLM Royal Dutch Airlines, legally ''Koninklijke Luchtvaart Maatschappij N.V.'' (literal translation: Royal Aviation Company Plc.), is the flag carrier airline of the Netherlands. KLM is headquartered in Amstelveen, with its hub at nearby Amste ...
as a pilot after completing his military service but chose to apply to
Harvard Medical School Harvard Medical School (HMS) is the graduate medical school of Harvard University and is located in the Longwood Medical Area of Boston, Massachusetts. Founded in 1782, HMS is one of the oldest medical schools in the United States and is consi ...
, which rejected him because he had received a D in college biology. He attended
Boston University Boston University (BU) is a private research university in Boston, Massachusetts. The university is nonsectarian, but has a historical affiliation with the United Methodist Church. It was founded in 1839 by Methodists with its original campu ...
for a year, taking the pre-med courses he had not taken as an undergraduate. He was finally accepted by Harvard Medical School, but spent an intervening year teaching at an elementary school in
South Carolina )''Animis opibusque parati'' ( for, , Latin, Prepared in mind and resources, links=no) , anthem = " Carolina";" South Carolina On My Mind" , Former = Province of South Carolina , seat = Columbia , LargestCity = Charleston , LargestMetro = ...
. He worked at a laundry to help pay for those medical school costs not covered by the
G.I. Bill The Servicemen's Readjustment Act of 1944, commonly known as the G.I. Bill, was a law that provided a range of benefits for some of the returning World War II veterans (commonly referred to as G.I.s). The original G.I. Bill expired in 1956, bu ...
.Martin, Douglas
"Dr. Thomas C. Peebles, Who Identified Measles Virus, Dies at 89"
''
The New York Times ''The New York Times'' (''the Times'', ''NYT'', or the Gray Lady) is a daily newspaper based in New York City with a worldwide readership reported in 2020 to comprise a declining 840,000 paid print subscribers, and a growing 6 million paid ...
'', August 4, 2010. Accessed August 4, 2010.
After completing medical school he did an internship and
residency Residency may refer to: * Domicile (law), the act of establishing or maintaining a residence in a given place ** Permanent residency, indefinite residence within a country despite not having citizenship * Residency (medicine), a stage of postgrad ...
in pediatrics at
Massachusetts General Hospital Massachusetts General Hospital (Mass General or MGH) is the original and largest teaching hospital of Harvard Medical School located in the West End neighborhood of Boston, Massachusetts. It is the third oldest general hospital in the United Stat ...
, where he later became a Chief Resident of Pediatrics. He was also a Fellow at Children's Hospital Boston, where he worked with Dr.
John Franklin Enders John Franklin Enders (February 10, 1897 – September 8, 1985) was an American biomedical scientist and Nobel Laureate. Enders has been called "The Father of Modern Vaccines." Life and education Enders was born in West Hartford, Connecticut on Fe ...
, known as "The Father of Modern Vaccines", who earned the Nobel Prize in 1954 for his research on cultivating the
polio virus A poliovirus, the causative agent of polio (also known as poliomyelitis), is a serotype of the species ''Enterovirus C'', in the family of ''Picornaviridae''. There are three poliovirus serotypes: types 1, 2, and 3. Poliovirus is composed of an ...
that led to the development of a vaccination for the disease. Switching to study measles, Peebles was sent to a Fay School where an outbreak of the disease was underway and was able to isolate the virus from some of the blood samples and throat swabs he took from students. Even after Enders had taken him off the study team, Peebles was able to cultivate the virus and show that the disease could be passed on to monkeys inoculated with the material he had collected. Enders was able to use the cultivated virus to develop a measles vaccine in 1963 based on the material isolated by Peebles. In the late 1950s and early 1960s, nearly twice as many children died from measles as from polio.Staff
"The Measles Vaccine"
''
The New York Times ''The New York Times'' (''the Times'', ''NYT'', or the Gray Lady) is a daily newspaper based in New York City with a worldwide readership reported in 2020 to comprise a declining 840,000 paid print subscribers, and a growing 6 million paid ...
'', March 28, 1963. Accessed August 4, 2010.
The vaccine for measles has led to the near-complete elimination of the disease in the United States and other developed countries. In a study he performed on the tetanus vaccine, he found that people were getting as much as 2,500 times the amount needed to provide protection, showing that the
booster dose A booster dose is an extra administration of a vaccine after an earlier (primer) dose. After initial immunization, a booster provides a re-exposure to the immunizing antigen. It is intended to increase immunity against that antigen back to protec ...
s could be given once every ten years, rather than yearly, while substantially reducing the risk of allergic reactions caused by the higher dosages in common use. In his private practice, he noticed that patients from towns where the water was fluoridated had fewer cavities. He conducted research and determined a dosage that was included as part of a regular vitamin. Peebles died at age 89 on July 8, 2010, in his home in
Port Charlotte, Florida Port Charlotte is an unincorporated community and census-designated place (CDP) in Charlotte County, Florida, United States. The population was 54,392 at the 2010 census. It is part of the Punta Gorda, Florida Metropolitan Statistical Area. Port C ...
. He was survived by his wife, the former Annie Diffley, as well as by a daughter, two sons and five grandchildren.


References

{{DEFAULTSORT:Peebles, Thomas C. 1921 births 2010 deaths United States Navy personnel of World War II American pediatricians Harvard Medical School alumni Harvard University alumni People from Newton, Massachusetts People from Port Charlotte, Florida Recipients of the Distinguished Flying Cross (United States) United States Navy officers American virologists Military personnel from Massachusetts