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Thiophene-2-acetic acid is the
organosulfur compound Organosulfur compounds are organic compounds that contain sulfur. They are often associated with foul odors, but many of the sweetest compounds known are organosulfur derivatives, e.g., saccharin. Nature abounds with organosulfur compounds—sulfu ...
with the formula HO2CCH2C4H3S. Together with thiophene-3-acetic acid, it is one of two isomeric thiophene acetic acids.


Preparation and use

It is prepared from
2-acetylthiophene 2-Acetylthiophene is an organosulfur compound with the formula CH3C(O)C4H3S. A yellow liquid, it is the more useful of the two isomers of acetylthiophene. It is of commercial interest as a precursor to both thiophene-2-carboxylic acid and thioph ...
. It is a precursor to the
antibiotic An antibiotic is a type of antimicrobial substance active against bacteria. It is the most important type of antibacterial agent for fighting bacterial infections, and antibiotic medications are widely used in the treatment and prevention of ...
s cephaloridine and
cephalothin Cefalotin (INN) or cephalothin (USAN) is a first-generation cephalosporin antibiotic. It was the first cephalosporin marketed (1964) and continues to be widely used. It is an intravenously administered agent with a similar antimicrobial spec ...
.{{cite book, first = Jonathan , last = Swanston , chapter = Thiophene , title = Ullmann's Encyclopedia of Industrial Chemistry , publisher = Wiley-VCH , location = Weinheim , date = 2006 , doi = 10.1002/14356007.a26_793.pub2, isbn = 3527306730 .


References

Thiophenes Carboxylic acids