Theodor Langhans (28 September 1839 – 22 October 1915) was a German

pathologist Pathology is the study of the causes and effects of disease or injury. The word ''pathology'' also refers to the study of disease in general, incorporating a wide range of biology research fields and medical practices. However, when used in t ...

who was a native of

Usingen Usingen is a small town in the Hochtaunuskreis in Hessen, Germany. Until 1972, this residential and school town was the seat of the former district of Usingen. Coat of arms The earliest seal whose appearance is known – there had been earlier on ...

Duchy of Nassau The Duchy of Nassau (German: ''Herzogtum Nassau'') was an independent state between 1806 and 1866, located in what is now the German states of Rhineland-Palatinate and Hesse. It was a member of the Confederation of the Rhine and later of the G ...

. He studied medicine at the

University of Heidelberg } Heidelberg University, officially the Ruprecht Karl University of Heidelberg, (german: Ruprecht-Karls-Universität Heidelberg; la, Universitas Ruperto Carola Heidelbergensis) is a public research university in Heidelberg, Baden-Württemberg, ...

, and at the

University of Göttingen The University of Göttingen, officially the Georg August University of Göttingen, (german: Georg-August-Universität Göttingen, known informally as Georgia Augusta) is a public research university in the city of Göttingen, Germany. Founded ...

under Friedrich Gustav Jakob Henle (1809–1885), at

Berlin Berlin ( , ) is the capital and List of cities in Germany by population, largest city of Germany by both area and population. Its 3.7 million inhabitants make it the European Union's List of cities in the European Union by population within ci ...

under

Rudolf Virchow Rudolf Ludwig Carl Virchow (; or ; 13 October 18215 September 1902) was a German physician, anthropologist, pathologist, prehistorian, biologist, writer, editor, and politician. He is known as "the father of modern pathology" and as the founder ...

(1821–1902) and in

Würzburg Würzburg (; Main-Franconian: ) is a city in the region of Franconia in the north of the German state of Bavaria. Würzburg is the administrative seat of the ''Regierungsbezirk'' Lower Franconia. It spans the banks of the Main River. Würzburg ...

, where he became an assistant to

Friedrich Daniel von Recklinghausen Friedrich Daniel von Recklinghausen (; December 2, 1833 – August 26, 1910) was a German pathologist born in Gütersloh, Westphalia. He was the father of physiologist Heinrich von Recklinghausen (1867–1942). Early life Recklinghausen was bo ...

(1833–1910). In 1867 he became a lecturer at the

University of Marburg The Philipps University of Marburg (german: Philipps-Universität Marburg) was founded in 1527 by Philip I, Landgrave of Hesse, which makes it one of Germany's oldest universities and the oldest still operating Protestant university in the wor ...

, and in 1872 became a full professor of

pathology Pathology is the study of the causes and effects of disease or injury. The word ''pathology'' also refers to the study of disease in general, incorporating a wide range of biology research fields and medical practices. However, when used in ...

at the

University of Giessen University of Giessen, official name Justus Liebig University Giessen (german: Justus-Liebig-Universität Gießen), is a large public research university in Giessen, Hesse, Germany. It is named after its most famous faculty member, Justus von ...

, where he succeeded Ludwig Franz Alexander Winther (1812–1871). From 1872 until 1912, Langhans was a professor of

pathological anatomy Anatomical pathology (''Commonwealth'') or Anatomic pathology (''U.S.'') is a medical specialty that is concerned with the diagnosis of disease based on the macroscopic, microscopic, biochemical, immunologic and molecular examination o ...

at the

University of Bern The University of Bern (german: Universität Bern, french: Université de Berne, la, Universitas Bernensis) is a university in the Swiss capital of Bern and was founded in 1834. It is regulated and financed by the Canton of Bern. It is a compreh ...

, where one of his assistants was surgeon Fritz de Quervain (1868–1940). He also worked with Serafina Schachova on kidney anatomy research using a canine model of induced nephritis. Langhans is remembered for his discovery of multi-nucleated giant cells that are found in granulomatous conditions, and are now referred to as

Langhans giant cell Langhans giant cells are large cells found in granulomatous conditions. They are formed by the fusion of epithelioid cells ( macrophages), and contain nuclei arranged in a horseshoe-shaped pattern in the cell periphery. Although traditionally ...

References

* This article is based on a translation of an article at the German Wikipedia, namely
Historischen Lexikon der Schweiz

Sarcoidosis Networking
1839 births 1915 deaths People from Usingen German pathologists Academic staff of the University of Giessen Academic staff of the University of Bern People from the Duchy of Nassau {{Germany-med-bio-stub