Theo Wallimann (born 13 October 1946 in

Alpnach Alpnach is a village in the canton of Obwalden in Switzerland. It comprises the villages of Alpnach Dorf, Alpnachstad and Schoried. History Alpnach is first mentioned about 870 as ''Alpenacho''. Geography Alpnach has an area, , of . Of this ar ...

Obwalden Obwalden, also Obwald (german: Kanton Obwalden, rm, Chantun Sursilvania; french: Canton d'Obwald; it, Canton Obvaldo), is one of the 26 cantons forming the Swiss Confederation. It is composed of seven municipalities and the seat of the govern ...

, Switzerland) is a Swiss biologist who was research group leader and Adjunct-Professor at the Institute of Cell Biology

ETH Zurich (colloquially) , former_name = eidgenössische polytechnische Schule , image = ETHZ.JPG , image_size = , established = , type = Public , budget = CHF 1.896 billion (2021) , rector = Günther Dissertori , president = Joël Mesot , ac ...

and later at the Institute of Molecular Health Science at the

at the Biology Department, of the

, Switzerland.

Research and career

In 1975, Theo Wallimann completed his Ph.D. Dissertation on “M-line-bound Creatine Kinase and Myofibrillar Structure” in the laboratory of Prof. Hans M. Eppenberger at the Institute of Cell Biology at

with distinction and received the ETH prize and medal. From 1975 - 1981, Wallimann worked as a post-doctoral research associate with Andrew G. Szent-Györgyi , at the Biology Department of

Brandeis University , mottoeng = "Truth even unto its innermost parts" , established = , type = Private research university , accreditation = NECHE , president = Ronald D. Liebowitz , pro ...

on the subject of "Myosin-linked calcium regulation of muscle contraction". After rejoining the Biology Dept of the

ETH-Zurich (colloquially) , former_name = eidgenössische polytechnische Schule , image = ETHZ.JPG , image_size = , established = , type = Public , budget = CHF 1.896 billion (2021) , rector = Günther Dissertori , president = Joël Mesot , ac ...

in 1981, Wallimann became a Lecturer in 1984 with his Habilitation on: "Localization and function of M-line-bound creatine kinase: M-band model and Phospho-Creatine Shuttle"). In 1994, Wallimann was awarded the title of Professor and in the next two years he became Head and Deputy Head of the Institute of Cell Biology. Wallimann was also awarded with Alfred-Vogt-Prize 2005. Wallimann resigned from his post in June 2008 and is now

Emeritus ''Emeritus'' (; female: ''emerita'') is an adjective used to designate a retired chair, professor, pastor, bishop, pope, director, president, prime minister, rabbi, emperor, or other person who has been "permitted to retain as an honorary title ...

and member of the ETH Alumni organisation. Wallimann's main areas of interest are: *The high-resolution atomic structure, molecular physiology and subcellular compartmentation of

creatine kinase Creatine kinase (CK), also known as creatine phosphokinase (CPK) or phosphocreatine kinase, is an enzyme () expressed by various tissues and cell types. CK catalyses the conversion of creatine and uses adenosine triphosphate (ATP) to create phosp ...

(CK) isoenzymes and of the Creatine Transporter (CRT), and in general, micro-compartmentation and metabolite channeling by multi-enzyme complexes. *The mechanisms of the cell enhancing and neuro-protective effects of creatine supplementation in health (muscle strength, learning and memory) and disease (neuromuscular and neuro-degenerative disorders).(see the recent Conference Volume on "Creatine Supplementation for Health and Clinical Diseases" (2022) https://exerciseandsportnutritionlab.com/news/creatine-in-health-book-published/ *The structure and molecular physiology of AMP-activated protein kinase (

AMPK AMPK may refer to: * AMP-activated protein kinase 5' AMP-activated protein kinase or AMPK or 5' adenosine monophosphate-activated protein kinase is an enzyme (EC 2.7.11.31) that plays a role in cellular energy homeostasis, largely to activate gl ...

), involved in cellular energy homeostasis and nutritional signalling, which is relevant for

type-2 diabetes Type 2 diabetes, formerly known as adult-onset diabetes, is a form of diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin. Common symptoms include increased thirst, frequent urination, ...

obesity Obesity is a medical condition, sometimes considered a disease, in which excess body fat has accumulated to such an extent that it may negatively affect health. People are classified as obese when their body mass index (BMI)—a person's we ...

metabolic syndrome Metabolic syndrome is a clustering of at least three of the following five medical conditions: abdominal obesity, high blood pressure, high blood sugar, high serum triglycerides, and low serum high-density lipoprotein (HDL). Metabolic syndrome ...

and

cancer Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. These contrast with benign tumors, which do not spread. Possible signs and symptoms include a lump, abnormal b ...

.(for publications in PubMed see: and ).

References

{{DEFAULTSORT:Wallimann, Theo 1946 births Cell biologists Swiss biologists Academic staff of ETH Zurich Living people Brandeis University alumni