The Llura Liggett Gund Award
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The Llura Liggett Gund Award honors researchers for career achievements that have significantly advanced the research and development of preventions, treatments and cures for
eye disease This is a partial list of human eye diseases and disorders. The World Health Organization publishes a classification of known diseases and injuries, the International Statistical Classification of Diseases and Related Health Problems, or ICD-10. ...
. The award is the highest tribute presented by the
Foundation Fighting Blindness The mission of the Foundation Fighting Blindness is to fund research that will lead to the prevention, treatment and cures for the entire spectrum of retinal degenerative diseases, including retinitis pigmentosa, macular degeneration, Usher syndro ...
, a nonprofit organization that funds research and clinical trials on eye disease. It is named after Llura Liggett Gund, a national trustee of the Foundation and wife of Gordon Gund, the Foundation’s cofounder and chairman. Awardees receive a custom-designed Steuben crystal sculpture. According to its citation, the award recognizes “an individual whose outstanding dedication and commitment to retinal science for 15 years or more has resulted in highly significant advancements or breakthroughs in retinal degenerative disease research.”


Recipients

The award is presented as warranted. *2016 - Richard Weleber, Casey Eye Institute, Oregon Health & Science University - for career achievement in the field of retinal-disease therapies. *2015 -
José-Alain Sahel José-Alain Sahel is a French ophthalmologist and scientist. He is currently the chair of the Department of Ophthalmology at the University of Pittsburgh School of Medicine, director of the UPMC Eye Center, and the Eye and Ear Foundation Chair of ...
, Institut de la Vision in Paris - for his work on vision-saving treatments and cures. *2013 - William W. Hauswirth, Ph.D., the Maida and Morris Rybaczki Professor of Ophthalmology at the
University of Florida College of Medicine The University of Florida College of Medicine is the medical school of the University of Florida. It is part of the J. Hillis Miller Health Science Center, with facilities in Gainesville and Jacksonville, Florida. The school grants Doctor ...
. He received the award for using non-harmful adeno-associated viruses (AAVs) to transport healthy DNA into retinal cells at the back of the eye, showing that gene therapy could restore vision in animal models, including Briard dogs. His team’s approach was then used in human clinical trials where children and young adults virtually blind from Leber congenital amaurosis (LCA) have had significant vision restored. *2012 - Edwin Stone, M.D., Ph.D., the Seamans-Hauser Chair of Molecular Ophthalmology at the University of Iowa. Dr. Stone’s lab has been a leader in discovering and characterizing genes that cause retinal degenerations such as retinitis pigmentosa, Leber congenital amaurosis, and Stargardt disease, among other conditions. He and his colleagues are taking the new genetic information, creating models of disease, and then working to develop potential treatments for evaluation in clinical trials. This effort includes successfully converting a patient’s skin cells to stem cells, and then to retinal precursor cells to evaluate possible therapies. *2011 - Robert E. Anderson, M.D., Ph.D., professor of ophthalmology and cell biology at the Dean A. McGee Eye Institute and Professor of Ophthalmology and the George Lynn Cross Research Professor at the University of Oklahoma Health Sciences Center. He and his colleagues discovered years ago that omega-3 fatty acids found in fish oils are important for the most efficient and fastest development of the visual system, leading to their inclusion in infant formulas today. *2009 - Dean Bok, Ph.D., received the award for his work defining the link between
vitamin A Vitamin A is a fat-soluble vitamin and an essential nutrient for humans. It is a group of organic compounds that includes retinol, retinal (also known as retinaldehyde), retinoic acid, and several provitamin A carotenoids (most notably bet ...
and vision. His research led the way in establishing the gene defect in the vitamin A metabolic cycle that ultimately directed researchers toward successful gene therapy clinical trials for
Leber congenital amaurosis Leber congenital amaurosis (LCA) is a rare inherited eye disease that appears at birth or in the first few months of life. It affects about 1 in 40,000 newborns. LCA was first described by Theodor Leber in the 19th century. It should not be co ...
, a severe, early onset form of
retinitis pigmentosa Retinitis pigmentosa (RP) is a genetic disorder of the eyes that causes loss of vision. Symptoms include trouble seeing at night and decreasing peripheral vision (side and upper or lower visual field). As peripheral vision worsens, people may ...
. *2007 - Matthew LaVail, Ph.D., received the award for his leadership role in understanding, identifying, and developing neuroprotective agents that slow or reverse vision loss. LaVail’s research has provided targets for the identification of dozens of potential treatments. *2001 - John Dowling, Ph.D., received the award for his groundbreaking work in understanding the functional organization of the
retina The retina (from la, rete "net") is the innermost, light-sensitive layer of tissue of the eye of most vertebrates and some molluscs. The optics of the eye create a focused two-dimensional image of the visual world on the retina, which then ...
, including synaptic organization, electrical responses of retinal neurons, and the exchange of retinoids in the visual cycle. Dowling's discoveries have been essential to the work of virtually every retinal researcher over the last several decades. *2000 - Eliot Berson, M.D., received the award for his discovery that
vitamin A palmitate Retinyl palmitate, or vitamin A palmitate, is the ester of retinol (vitamin A) and palmitic acid, with formula C36H60O2. It is the most abundant form of vitamin A storage in animals. An alternate spelling, retinol palmitate, which violates the - ...
slows the rate of vision loss in people with retinitis pigmentosa (RP). As the only treatment for RP, vitamin A can potentially provide many additional years of useful vision. *1998 - Alan Laties, M.D., received the award in recognition of his career as a world-renowned neuro-ophthalmologist, neuro-ophthalmologic investigator, and educator in retinal science.


See also

*
List of medicine awards This list of medicine awards is an index to articles about notable awards for contributions to medicine, the science and practice of establishing the diagnosis, prognosis, treatment, and prevention of disease. The list is organized by region and ...


References


External links


Award Web page
{{DEFAULTSORT:Llura Liggett Gund Award Medicine awards Awards established in 1998 American awards