"The cream" is a

testosterone Testosterone is the primary sex hormone and anabolic steroid in males. In humans, testosterone plays a key role in the development of Male reproductive system, male reproductive tissues such as testes and prostate, as well as promoting secondar ...

-based ointment that is used in conjunction with

anabolic steroids Anabolic steroids, also known more properly as anabolic–androgenic steroids (AAS), are steroidal androgens that include natural androgens like testosterone as well as synthetic androgens that are structurally related and have similar effects t ...

such as

tetrahydrogestrinone Tetrahydrogestrinone (THG), known by the nickname The Clear, is a synthetic and orally active anabolic–androgenic steroid (AAS) which was never marketed for medical use. It was developed by Patrick Arnold and was used by a number of high-profi ...

(THG, also known as "the clear") in order to mask doping in professional athletes. The drug was made public when the

United States Anti-Doping Agency The United States Anti-Doping Agency (USADA, ) is a non-profit, non-governmental 501(c)(3) organization and the national anti- doping organization (NADO) for the United States. To protect clean competition and the integrity of sport and prevent ...

was contacted by an anonymous athletics coach, later identified as

Trevor Graham Trevor Graham (born 20 August 1963) is a Jamaican-born American former sprinter and athletics coach. Following the BALCO scandal, the US Olympic Committee barred him indefinitely from all its training sites. Athletics career Graham was ...

, who claimed that several top athletes were using THG as an illegal performance enhancing drug. After an investigation, it was revealed that many top

baseball Baseball is a bat-and-ball sport played between two teams of nine players each, taking turns batting and fielding. The game occurs over the course of several plays, with each play generally beginning when a player on the fielding tea ...

athletes were connected with THG; the list included stars such as

Jason Giambi Jason Gilbert Giambi (; born January 8, 1971) is an American former professional baseball first baseman and designated hitter. In his Major League Baseball (MLB) career, which began in 1995, Giambi played for the Oakland Athletics, New York Yank ...

, who would also confess to using

human growth hormone Growth hormone (GH) or somatotropin, also known as human growth hormone (hGH or HGH) in its human form, is a peptide hormone that stimulates growth, cell reproduction, and cell regeneration in humans and other animals. It is thus important in h ...

and

Gary Sheffield Gary Antonian Sheffield (born November 18, 1968) is an American former professional baseball outfielder who played in Major League Baseball for eight teams from 1988 to 2009. He is a sports agent. For most of his career, Sheffield played right ...

, who admitted using the cream and the clear, albeit unknowingly. When questioned about the substance, athletes said that the two substances were identified only as "the cream" and "the clear". It was later determined that the

Bay Area Laboratory Co-operative The Bay Area Laboratory Co-operative (BALCO) (1984–2003) was an American company led by founder and owner Victor Conte. In 2003, journalists Lance Williams and Mark Fainaru-Wada investigated the company's role in a drug sports scandal later re ...

, which supplied THG, had provided it in conjunction with "the cream" in order to increase the overall steroid content of the body. It had been distributed to several athletes by trainer Greg Anderson.

Composition

affidavit An ( ; Medieval Latin for "he has declared under oath") is a written statement voluntarily made by an ''affiant'' or '' deponent'' under an oath or affirmation which is administered by a person who is authorized to do so by law. Such a statemen ...

from the United States Anti-Doping Agency (USADA) reveals that "the cream" was a composition of testosterone and

epitestosterone Epitestosterone, or isotestosterone, also known as 17α-testosterone or as androst-4-en-17α-ol-3-one, is an endogenous steroid and an epimer of the androgen sex hormone testosterone. It is a weak competitive antagonist of the androgen recepto ...

designed to increase the natural level of the

steroid A steroid is a biologically active organic compound with four rings arranged in a specific molecular configuration. Steroids have two principal biological functions: as important components of cell membranes that alter membrane fluidity; and a ...

testosterone while not disrupting the ratio of testosterone to epitestosterone, a common metric used in traditional drug tests.

References

* {{DEFAULTSORT:Cream Drugs in sport Testosterone