Terri Attwood
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Teresa K. Attwood is a Professor of
Bioinformatics Bioinformatics () is an interdisciplinary field that develops methods and software tools for understanding biological data, in particular when the data sets are large and complex. As an interdisciplinary field of science, bioinformatics combi ...
in the Department of Computer Science and
School of Biological Sciences School of Biological Sciences may refer to: *Cold Spring Harbor Laboratory School of Biological Sciences * Irell & Manella Graduate School of Biological Sciences * School of Biological Sciences, University of Manchester *UCI School of Biological Sc ...
at the
University of Manchester , mottoeng = Knowledge, Wisdom, Humanity , established = 2004 – University of Manchester Predecessor institutions: 1956 – UMIST (as university college; university 1994) 1904 – Victoria University of Manchester 1880 – Victoria Univer ...
and a visiting
fellow A fellow is a concept whose exact meaning depends on context. In learned or professional societies, it refers to a privileged member who is specially elected in recognition of their work and achievements. Within the context of higher education ...
at the European Bioinformatics Institute (EMBL-EBI). She held a
Royal Society University Research Fellowship __NOTOC__ The Royal Society University Research Fellowship (URF) is a research fellowship awarded to outstanding early career scientists in the United Kingdom who are judged by the Royal Society to have the potential to become leaders in their fie ...
at University College London (UCL) from 1993 to 1999 and at the University of Manchester from 1999 to 2002.


Education

Attwood gained her
Bachelor of Science A Bachelor of Science (BS, BSc, SB, or ScB; from the Latin ') is a bachelor's degree awarded for programs that generally last three to five years. The first university to admit a student to the degree of Bachelor of Science was the University of ...
in
Biophysics Biophysics is an interdisciplinary science that applies approaches and methods traditionally used in physics to study biological phenomena. Biophysics covers all scales of biological organization, from molecular to organismic and populations. ...
from the
University of Leeds , mottoeng = And knowledge will be increased , established = 1831 – Leeds School of Medicine1874 – Yorkshire College of Science1884 - Yorkshire College1887 – affiliated to the federal Victoria University1904 – University of Leeds , ...
in 1982. She was awarded a PhD, also in Biophysics, two years later, in 1984 under the supervision of John E. Lydon studying chromonic
mesophase In chemistry and chemical physics, a mesophase is a state of matter intermediate between liquid and solid. Gelatin is a common example of a partially ordered structure in a mesophase. Further, biological structures such as the lipid bilayers of cel ...
s.


Research and career

Attwood undertook
postdoctoral research A postdoctoral fellow, postdoctoral researcher, or simply postdoc, is a person professionally conducting research after the completion of their doctoral studies (typically a PhD). The ultimate goal of a postdoctoral research position is to p ...
at Leeds until 1993, when she moved to
University College London , mottoeng = Let all come who by merit deserve the most reward , established = , type = Public research university , endowment = £143 million (2020) , budget = ...
for five years before moving to the
University of Manchester , mottoeng = Knowledge, Wisdom, Humanity , established = 2004 – University of Manchester Predecessor institutions: 1956 – UMIST (as university college; university 1994) 1904 – Victoria University of Manchester 1880 – Victoria Univer ...
in 1999. Her research concerns protein
sequence alignment In bioinformatics, a sequence alignment is a way of arranging the sequences of DNA, RNA, or protein to identify regions of similarity that may be a consequence of functional, structural, or evolutionary relationships between the sequences. Alig ...
and
protein analysis Proteomics is the large-scale study of proteins. Proteins are vital parts of living organisms, with many functions such as the formation of structural fibers of muscle tissue, enzymatic digestion of food, or synthesis and replication of DNA. In ...
. Inspired by the creation of
PROSITE PROSITE is a protein database. It consists of entries describing the protein families, domains and functional sites as well as amino acid patterns and profiles in them. These are manually curated by a team of the Swiss Institute of Bioinformati ...
, Attwood developed a method of protein fingerprinting and used this to establish the
PRINTS In molecular biology, the PRINTS database is a collection of so-called "fingerprints": it provides both a detailed annotation resource for protein families, and a diagnostic tool for newly determined sequences. A fingerprint is a group of conserve ...
database. With
Amos Bairoch Amos Bairoch (born 22 November 1957) is a Swiss bioinformatician and Professor of Bioinformatics at the Department of Human Protein Sciences of the University of Geneva where he leads the CALIPHO group at the Swiss Institute of Bioinformatics ( ...
she sought to unify work on
protein family A protein family is a group of evolutionarily related proteins. In many cases, a protein family has a corresponding gene family, in which each gene encodes a corresponding protein with a 1:1 relationship. The term "protein family" should not be c ...
classification and annotation, eventually jointly securing a
European Union The European Union (EU) is a supranational political and economic union of member states that are located primarily in Europe. The union has a total area of and an estimated total population of about 447million. The EU has often been des ...
grant with
Rolf Apweiler Rolf Apweiler is a director of European Bioinformatics Institute (EBI) part of the European Molecular Biology Laboratory (EMBL) with Ewan Birney. Education Apweiler gained his PhD in biochemistry from Heidelberg University. Research Apweiler has ...
to establish
InterPro InterPro is a database of protein families, protein domains and functional sites in which identifiable features found in known proteins can be applied to new protein sequences in order to functionally characterise them. The contents of InterPro ...
, with
Pfam Pfam is a database of protein families that includes their annotations and multiple sequence alignments generated using hidden Markov models. The most recent version, Pfam 35.0, was released in November 2021 and contains 19,632 families. Uses ...
, ProDom and Swiss-Prot/TrEMBL as consortium partners in 1997. Attwood has led major projects including the BioMinT FP5 text-mining consortium, the EMBER bioinformatics education consortium (including
EBI Ebrahim Hamedi ( fa, اِبراهیم حامدی, also Romanized as "Ebrāhim Hāmedi"; born 1949), better known by his stage name Ebi (Persian: ), is an Iranian pop singer who first started his career in Tehran, gaining fame as part of a ban ...
and
Swiss Institute of Bioinformatics The SIB Swiss Institute of Bioinformatics is an academic not-for-profit foundation which federates bioinformatics activities throughout Switzerland. The institute was established on 30 March 1998 and its mission is to provide core bioinfor ...
as partners), and the
EPSRC The Engineering and Physical Sciences Research Council (EPSRC) is a British Research Council that provides government funding for grants to undertake research and postgraduate degrees in engineering and the physical sciences, mainly to universi ...
PARADIGM Platform. She is the Manchester
principal investigator In many countries, the term principal investigator (PI) refers to the holder of an independent grant and the lead researcher for the grant project, usually in the sciences, such as a laboratory study or a clinical trial. The phrase is also often us ...
on projects SeqAhead (
Next-generation sequencing Massive parallel sequencing or massively parallel sequencing is any of several high-throughput approaches to DNA sequencing using the concept of massively parallel processing; it is also called next-generation sequencing (NGS) or second-generation s ...
data analysis network) and AllBio (bioinformatics infrastructure for unicellular, animal and plant sciences), and was also Manchester PI on EMBRACE and EuroKUP (kidney and urine proteomics). Attwood was a member of ELIXIR's Bioinformatics Training Strategy Committee (Work Package 11) during ELIXIR's preparatory phase. She is currently Chair of the
EMBnet The European Molecular Biology network (EMBnet) is an international scientific network and interest group that aims to enhance bioinformatics services by bringing together bioinformatics expertises and capacities. On 2011 EMBnet has 37 nodes spread ...
Global Bioinformatics Network, she was a member of the Executive Committees of the
International Society for Biocuration The International Society for Biocuration (ISB) is a non-profit organisation that promotes the field of biocuration and was founded in early 2009. It provides a forum for information exchange through meetings and workshops. The society's conferen ...
, and the Bioinformatics Training Network, and was recently elected to the Board of Directors of the International Society for Computational Biology. In 2012, she spearheaded the establishment of a GOBLET (Global Organisation for Bioinformatics Learning, Education and Training), with the major bioinformatics, computational biology and biocuration societies, networks and organisations as partners. , Attwood is the Chair of the
GOBLET A chalice (from Latin 'mug', borrowed from Ancient Greek () 'cup') or goblet is a footed cup intended to hold a drink. In religious practice, a chalice is often used for drinking during a ceremony or may carry a certain symbolic meaning. Re ...
Executive Board. As well as being a
biocurator Biocuration is the field of life sciences dedicated to organizing biomedical data, information and knowledge into structured formats, such as spreadsheets, tables and knowledge graphs. The biocuration of biomedical knowledge is made possible by the ...
http://www.biocurator.org/elec/candidates2011/Attwood.pdf Attwood biography from biocurator.org she has co-developed tools to align and visualise protein sequences and structures, including Ambrosia and CINEMA. The group are building re-usable software components to create useful bioinformatics applications through
UTOPIA (Bioinformatics tools) UTOPIA (User-friendly Tools for Operating Informatics Applications) is a suite of free tools for visualising and analysing bioinformatics data. Based on an ontology-driven data model, it contains applications for viewing and aligning protein sequ ...
, and are developing new approaches for automatic annotation and
text mining Text mining, also referred to as ''text data mining'', similar to text analytics, is the process of deriving high-quality information from text. It involves "the discovery by computer of new, previously unknown information, by automatically extract ...
, like PRECIS, METIS, BioIE, and semantic approaches to data integration, such as the Semantic
Biochemical Journal The ''Biochemical Journal'' is a peer-reviewed scientific journal which covers all aspects of biochemistry, as well as cell and molecular biology. It is published by Portland Press and was established in 1906. History The journal was established i ...
published by
Portland Press Portland Press Limited is the wholly owned publishing subsidiary of The Biochemical Society. It is a publisher of journals and books in the cellular and molecular life sciences. The surplus from the sales of its publications are returned to the s ...
. The UTOPIA tools underpin both the Semantic
Biochemical Journal The ''Biochemical Journal'' is a peer-reviewed scientific journal which covers all aspects of biochemistry, as well as cell and molecular biology. It is published by Portland Press and was established in 1906. History The journal was established i ...
and a collaborative project with
Pfizer Pfizer Inc. ( ) is an American multinational pharmaceutical and biotechnology corporation headquartered on 42nd Street in Manhattan, New York City. The company was established in 1849 in New York by two German entrepreneurs, Charles Pfizer ...
and
AstraZeneca AstraZeneca plc () is a British-Swedish multinational pharmaceutical and biotechnology company with its headquarters at the Cambridge Biomedical Campus in Cambridge, England. It has a portfolio of products for major diseases in areas includin ...
to develop a 21st-century interface to biomedical literature and data management. Attwood's research has received funding from the
Engineering and Physical Sciences Research Council The Engineering and Physical Sciences Research Council (EPSRC) is a British Research Council that provides government funding for grants to undertake research and postgraduate degrees in engineering and the physical sciences, mainly to universi ...
, the
Biotechnology and Biological Sciences Research Council Biotechnology and Biological Sciences Research Council (BBSRC), part of UK Research and Innovation, is a non-departmental public body (NDPB), and is the largest UK public funder of non-medical bioscience. It predominantly funds scientific rese ...
, the
Wellcome Trust The Wellcome Trust is a charitable foundation focused on health research based in London, in the United Kingdom. It was established in 1936 with legacies from the pharmaceutical magnate Henry Wellcome (founder of one of the predecessors of Glaxo ...
, the
Royal Society The Royal Society, formally The Royal Society of London for Improving Natural Knowledge, is a learned society and the United Kingdom's national academy of sciences. The society fulfils a number of roles: promoting science and its benefits, re ...
, the
European Union The European Union (EU) is a supranational political and economic union of member states that are located primarily in Europe. The union has a total area of and an estimated total population of about 447million. The EU has often been des ...
and industry.Terri Attwood's


Teaching

Attwood teaches on
undergraduate Undergraduate education is education conducted after secondary education and before postgraduate education. It typically includes all postsecondary programs up to the level of a bachelor's degree. For example, in the United States, an entry-lev ...
and
postgraduate Postgraduate or graduate education refers to academic or professional degrees, certificates, diplomas, or other qualifications pursued by post-secondary students who have earned an undergraduate ( bachelor's) degree. The organization and stru ...
courses and has been
doctoral advisor A doctoral advisor (also dissertation director, dissertation advisor; or doctoral supervisor) is a member of a university faculty whose role is to guide graduate students who are candidates for a doctorate, helping them select coursework, as well ...
or co-supervisor to several PhD students (e.g.,
Manuel Corpas Manuel Corpas (born December 3, 1982) is a Panamanian professional baseball pitcher for the Martinez Sturgeon of the Pecos League. He previously played in Major League Baseball (MLB) for the Colorado Rockies and Chicago Cubs. Career Colorado R ...
). Attwood has co-authored several book chapters and three popular bioinformatics textbooks: ''Introduction to Bioinformatics'' and ''Bioinformatics and Molecular Evolution''. Attwood is a co-author of the
bioinformatics Bioinformatics () is an interdisciplinary field that develops methods and software tools for understanding biological data, in particular when the data sets are large and complex. As an interdisciplinary field of science, bioinformatics combi ...
textbook ''Bioinformatics Challenges at the Interface of Biology and Computer Science: Mind the Gap'' with Steve Pettifer and Dave Thorne.


Academic service

Attwood serves on the
editorial board The editorial board is a group of experts, usually at a publication, who dictate the tone and direction the publication's editorial policy will take. Mass media At a newspaper, the editorial board usually consists of the editorial page editor, a ...
of the ''
Biochemical Journal The ''Biochemical Journal'' is a peer-reviewed scientific journal which covers all aspects of biochemistry, as well as cell and molecular biology. It is published by Portland Press and was established in 1906. History The journal was established i ...
'', '' Database: The Journal of Biological Databases and Curation'', ''Molecular and Cellular Proteomics'', the ''Journal of Molecular Graphics and Modelling'' and the ''EMBnet.journal.''


Awards and honours

Attwood held a
Royal Society University Research Fellowship __NOTOC__ The Royal Society University Research Fellowship (URF) is a research fellowship awarded to outstanding early career scientists in the United Kingdom who are judged by the Royal Society to have the potential to become leaders in their fie ...
(URF) from 1993 to 2002.


References

{{DEFAULTSORT:Attwood, Teresa K. Academics of the University of Manchester Living people Alumni of the University of Leeds British women computer scientists British bioinformaticians People associated with the Department of Computer Science, University of Manchester 20th-century British women scientists 21st-century British women scientists 1959 births