Teflurane
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Teflurane (
INN Inns are generally establishments or buildings where travelers can seek lodging, and usually, food and drink. Inns are typically located in the country or along a highway; before the advent of motorized transportation they also provided accommo ...
,
USAN 280px, "Samguk Sagi" Book 04. Silla's Records. In 512, Usan-guk(于山國)was Ulleungdo(鬱陵島) Usan-guk, or the State of Usan, occupied Ulleung-do and the adjacent islands during the Korean Three Kingdoms period. According to th ...
, code name Abbott 16900) is a
halocarbon Halocarbon compounds are chemicals in which one or more carbon atoms are linked by covalent bonds with one or more halogen atoms (fluorine, chlorine, bromine or iodine – ) resulting in the formation of organofluorine compounds, organochlori ...
drug A drug is any chemical substance that causes a change in an organism's physiology or psychology when consumed. Drugs are typically distinguished from food and substances that provide nutritional support. Consumption of drugs can be via insuffla ...
which was investigated as an
inhalational anesthetic An inhalational anesthetic is a chemical compound possessing general anesthetic properties that can be delivered via inhalation. They are administered through a face mask, laryngeal mask airway or tracheal tube connected to an anaesthetic vapori ...
but was never marketed. Its clinical development was terminated due to a high incidence of
cardiac arrhythmia Arrhythmias, also known as cardiac arrhythmias, heart arrhythmias, or dysrhythmias, are irregularities in the heartbeat, including when it is too fast or too slow. A resting heart rate that is too fast – above 100 beats per minute in adults ...
s in patients, similarly to the cases of
halopropane Halopropane (synonym FHD-3, trade name Tebron) is a halocarbon drug which was investigated as an inhalational anesthetic but was never marketed. Its clinical development was terminated due to a high incidence of cardiac arrhythmias in patients, s ...
and
norflurane 1,1,1,2-Tetrafluoroethane (also known as norflurane ( INN), R-134a, Freon 134a, Forane 134a, Genetron 134a, Green Gas, Florasol 134a, Suva 134a, or HFC-134a) is a hydrofluorocarbon (HFC) and haloalkane refrigerant with thermodynamic properties s ...
.


Chemistry

Teflurane is 2-bromo-1,1,1,2-tetrafluoroethane, a
haloalkane The haloalkanes (also known as halogenoalkanes or alkyl halides) are alkanes containing one or more halogen substituents. They are a subset of the general class of halocarbons, although the distinction is not often made. Haloalkanes are widely us ...
. It is a gas at standard conditions. The compound is chiral.


See also

*
Aliflurane Aliflurane (code name Hoechst Compound 26 or 26-P) is a halocarbon drug which was investigated as an inhalational anesthetic but was never marketed. See also * Halopropane * Norflurane * Roflurane * Synthane * Teflurane Teflurane (Internat ...
*
Roflurane Roflurane ( INN, USAN, code name DA-893) is a halocarbon drug which was investigated as an inhalational anesthetic but was never marketed. See also * Aliflurane * Halopropane * Norflurane * Synthane * Teflurane Teflurane (International Nonp ...
*
Synthane Synthane (code name BAX-3224) is a halocarbon agent which was investigated as an inhalational anesthetic but was never marketed. See also * Aliflurane * Halopropane * Norflurane * Roflurane * Teflurane Teflurane (International Nonproprietary ...


References

General anesthetics Organobromides Organofluorides GABAA receptor positive allosteric modulators Trifluoromethyl compounds {{nervous-system-drug-stub