Tefibazumab (named Aurexis but not approved) is a
humanized monoclonal antibody
Humanized antibodies are antibodies from non-human species whose protein sequences have been modified to increase their similarity to antibody variants produced naturally in humans. The process of "humanization" is usually applied to monoclonal an ...
for the treatment of severe infections with ''
Staphylococcus aureus''. Possible indications include the treatment of ''S. aureus'' in a phase 2a patients with
cystic fibrosis and of
methicillin-resistant ''S. aureus''.
It was developed by Inhibitex.
See also
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MSCRAMM
MSCRAMM (acronym for "microbial surface components recognizing adhesive matrix molecules") adhesin proteins mediate the initial attachment of bacteria to host tissue, providing a critical step to establish infection.
Examples include protein A, cl ...
(microbial surface components recognizing adhesive matrix molecules)
References
Monoclonal antibodies
Experimental drugs
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