Tanshinones are a class of chemical compounds. Examples include

dihydrotanshinone Dihydrotanshinone I (DI) is a naturally occurring compound extracted from ''Salvia miltiorrhiza'' Bunge, also known as Chinese sage, red sage root, and the Chinese herbal Dan Shen. It belongs to a class of lipophilic abietane diterpenoids and has ...

tanshinone I Tanshinones are a class of chemical compounds. Examples include dihydrotanshinone, tanshinone I, or tanshinone IIA. These compounds are all naturally occurring and can all be isolated from ''Salvia miltiorrhiza''. Dihydrotanshinone I has been r ...

, or

tanshinone IIA Tanshinones are a class of chemical compounds. Examples include dihydrotanshinone, tanshinone I, or tanshinone IIA. These compounds are all naturally occurring and can all be isolated from ''Salvia miltiorrhiza''. Dihydrotanshinone I has been ...

. These compounds are all naturally occurring and can all be isolated from ''

Salvia miltiorrhiza ''Salvia miltiorrhiza'' (), also known as red sage, Chinese sage, tan shen, or danshen, is a perennial plant in the genus ''Salvia'', highly valued for its roots in traditional Chinese medicine. Native to China and Japan, it grows at elevation, ...

''. Dihydrotanshinone I has been reported to have

cytotoxic Cytotoxicity is the quality of being toxic to cells. Examples of toxic agents are an immune cell or some types of venom, e.g. from the puff adder (''Bitis arietans'') or brown recluse spider (''Loxosceles reclusa''). Cell physiology Treating cells ...

ity to a variety of tumor cells. Tanshinone I is

anti-inflammatory Anti-inflammatory is the property of a substance or treatment that reduces inflammation or swelling. Anti-inflammatory drugs, also called anti-inflammatories, make up about half of analgesics. These drugs remedy pain by reducing inflammation as o ...

, and modulates or prevents

breast cancer Breast cancer is cancer that develops from breast tissue. Signs of breast cancer may include a lump in the breast, a change in breast shape, dimpling of the skin, milk rejection, fluid coming from the nipple, a newly inverted nipple, or a re ...

metastasis Metastasis is a pathogenic agent's spread from an initial or primary site to a different or secondary site within the host's body; the term is typically used when referring to metastasis by a cancerous tumor. The newly pathological sites, then, ...

by regulating

adhesion molecule Cell adhesion molecules (CAMs) are a subset of cell surface proteins that are involved in the binding of cells with other cells or with the extracellular matrix (ECM), in a process called cell adhesion. In essence, CAMs help cells stick to each ...

s. Tanshinone IIA is anti-inflammatory, an

antioxidant Antioxidants are compounds that inhibit oxidation, a chemical reaction that can produce free radicals. This can lead to polymerization and other chain reactions. They are frequently added to industrial products, such as fuels and lubricant ...

, and cytotoxic against a variety of

cell line An immortalised cell line is a population of cells from a multicellular organism which would normally not proliferate indefinitely but, due to mutation, have evaded normal cellular senescence and instead can keep undergoing division. The cell ...

References

External links

* {{commons category inline, Tanshinones, lcfirst=yes Furans