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Tang Feifan (; July 23, 1897 – September 30, 1958) was a Chinese
medical Medicine is the science and practice of caring for a patient, managing the diagnosis, prognosis, prevention, treatment, palliation of their injury or disease, and promoting their health. Medicine encompasses a variety of health care practic ...
microbiologist A microbiologist (from Ancient Greek, Greek ) is a scientist who studies microscopic life forms and processes. This includes study of the growth, interactions and characteristics of Microorganism, microscopic organisms such as bacteria, algae, f ...
best known for culturing the ''Chlamydia trachomatis'' agent in the yolk sacs of eggs. Tang was persecuted during the "Pulling Out Bourgeois White Flag Movement" and committed suicide in 1958.


Biography


Early life

Tang was born Tang Ruizhao () in Tangjiaping Village of
Liling Liling () is a county-level city and the 12th most populous county-level division in Hunan Province, China; it is under the administration of the prefecture-level city of Zhuzhou. Located on the middle eastern margin of the province, the city i ...
,
Hunan Hunan (, ; ) is a landlocked province of the People's Republic of China, part of the South Central China region. Located in the middle reaches of the Yangtze watershed, it borders the province-level divisions of Hubei to the north, Jiangxi to ...
, on July 23, 1897, to a relatively poor gentry family, during the
Qing Empire The Qing dynasty ( ), officially the Great Qing,, was a Manchu-led imperial dynasty of China and the last orthodox dynasty in Chinese history. It emerged from the Later Jin dynasty founded by the Jianzhou Jurchens, a Tungusic-speak ...
. He was the second of three children. He had a younger brother, Tang Qiufan (). His father Tang Luquan () taught at a family friend He Zhongshan's () old-style private school, in which Tang Feifan studied poetry, history, philosophy, mathematics, and natural science. His son,
He Jian He Jian (; 10 April 1887 – 25 April 1956) was a Chinese Nationalist (KMT) general and politician in the Republic of China. He was governor of Hunan province between 1929 and 1937, and Interior Minister from 1937 to 1939. He was best known for ...
, became Tang Feifan's close friend. "Learning from the West with its advanced science and technology;Invigorating the Chinese nation", Tang had often heard the hometown folks talk about reform and revolution in his childhood. When China was often called the "
sick man of Asia The phrase "Sick man of Asia" (), or "Sick man of East Asia" () when referring specifically to China, is a term denoting a country in Asia undergoing economic or political strife. It originally referred to Qing China in the late 19th and early 20 ...
", Tang determined to study medicine science.


Education

At the age of twelve, he attended Chengnan School in Changsha, capital of Hunan province. After graduating from the Xiangya Medical College (now part of
Central South University Central South University (CSU; ) is a national public university in Changsha, Hunan, China. The university is sponsored by the Ministry of Education of the People's Republic of China, China Ministry of Education. It is a Chinese state Double Fir ...
) in 1921, he earned his doctoral degree in medical science from
Yale University Yale University is a private research university in New Haven, Connecticut. Established in 1701 as the Collegiate School, it is the third-oldest institution of higher education in the United States and among the most prestigious in the wo ...
. He went back to China in 1921 and that year studied, then taught at
Peking Union Medical College Peking Union Medical College (), founded in 1906, is a selective public medical college based in Dongcheng, Beijing, China. It is a Chinese Ministry of Education Double First Class University Plan The World First Class University and First ...
. In 1925 he went to the United States again to study
bacteriology Bacteriology is the branch and specialty of biology that studies the morphology, ecology, genetics and biochemistry of bacteria as well as many other aspects related to them. This subdivision of microbiology involves the identification, classificat ...
under Professor
Hans Zinsser Hans Zinsser (November 17, 1878 – September 4, 1940) was an American physician, bacteriologist, and prolific author. The author of over 200 books and medical articles, he was also a published poet. Some of his verses were published in '' ...
at
Harvard University Harvard University is a private Ivy League research university in Cambridge, Massachusetts. Founded in 1636 as Harvard College and named for its first benefactor, the Puritan clergyman John Harvard, it is the oldest institution of higher le ...
. He returned to China in 1929 and in the meantime became professor at Medical School of
National Central University National Central University (NCU, ; Pha̍k-fa-sṳ: ''Kwet-li̍p Chung-yong Thài-ho̍k'', Wade–Giles: ''Kuo2 Li4 Chung Yang Ta4 Hsüeh2'' or ''中大'', ''Chung-ta'') is a public research university with long-standing traditions based in Taiwa ...
. In 1935 he was recruited as a researcher at the British National Institute for Medical Research, a position in which he remained until 1937.


Second Sino-Japanese War

After the outbreak of the
Second Sino-Japanese War The Second Sino-Japanese War (1937–1945) or War of Resistance (Chinese term) was a military conflict that was primarily waged between the Republic of China and the Empire of Japan. The war made up the Chinese theater of the wider Pacific Th ...
in 1938, he founded the Central Epidemic Prevention Laboratory in
Kunming Kunming (; ), also known as Yunnan-Fu, is the capital and largest city of Yunnan province, China. It is the political, economic, communications and cultural centre of the province as well as the seat of the provincial government. The headquar ...
, capital of
southwest China Southwest China () is a region in the south of the People's Republic of China. Geography Southwest China is a rugged and mountainous region, transitioning between the Tibetan Plateau to the west and the Chinese coastal hills (东南丘陵) and ...
's
Yunnan Yunnan , () is a landlocked Provinces of China, province in Southwest China, the southwest of the People's Republic of China. The province spans approximately and has a population of 48.3 million (as of 2018). The capital of the province is ...
province, and served as its director. He made China's first batch of
penicillin Penicillins (P, PCN or PEN) are a group of β-lactam antibiotics originally obtained from ''Penicillium'' moulds, principally '' P. chrysogenum'' and '' P. rubens''. Most penicillins in clinical use are synthesised by P. chrysogenum using ...
and serum with his team for the soldiers at the front. After war he established China's first antibiotic research and
penicillin Penicillins (P, PCN or PEN) are a group of β-lactam antibiotics originally obtained from ''Penicillium'' moulds, principally '' P. chrysogenum'' and '' P. rubens''. Most penicillins in clinical use are synthesised by P. chrysogenum using ...
production workshop, as well as normal
BCG vaccine Bacillus Calmette–Guérin (BCG) vaccine is a vaccine primarily used against tuberculosis (TB). It is named after its inventors Albert Calmette and Camille Guérin. In countries where tuberculosis or leprosy is common, one dose is recommended ...
laboratory. In 1947 he paid a fact-finding visit to the
United Kingdom The United Kingdom of Great Britain and Northern Ireland, commonly known as the United Kingdom (UK) or Britain, is a country in Europe, off the north-western coast of the continental mainland. It comprises England, Scotland, Wales and North ...
, attended the 4th World Conference of
International Union of Microbiological Societies The International Union of Microbiological Societies (IUMS), founded in 1927 as the International Society of Microbiology, is one of 40 member unions and associations of the International Science Council (ISC), and was formerly under ISC's pred ...
(IUMS) in the
Kingdom of Denmark The Danish Realm ( da, Danmarks Rige; fo, Danmarkar Ríki; kl, Danmarkip Naalagaaffik), officially the Kingdom of Denmark (; ; ), is a sovereign state located in Northern Europe and Northern North America. It consists of Denmark, metropolitan ...
, and became its standing committee.


People's Republic era

After the establishment of the Communist State, Tang successively served as director of Institute of Biological Products of the Ministry of Health, director of
Chinese Medical Association In China, the practice of medicine is a mixture of government, charitable, and private institutions, while many people rely on traditional medicine. Until reforms in the late twentieth and early twenty-first century, physicians were quasi-governm ...
, and director general of Chinese Society for Microbiology. In 1950 he joined the newly created National Institute for the Control of Pharmaceutical and Biological Products, working as its director. During his time in office, he directed to develop China's first biological products specification - ''Verification Regulation of Biological Products'' (). That same year, a terrible
plague Plague or The Plague may refer to: Agriculture, fauna, and medicine *Plague (disease), a disease caused by ''Yersinia pestis'' * An epidemic of infectious disease (medical or agricultural) * A pandemic caused by such a disease * A swarm of pes ...
hit the whole
north China North China, or Huabei () is a List of regions of China, geographical region of China, consisting of the provinces of Beijing, Tianjin, Hebei, Shanxi and Inner Mongolia. Part of the larger region of Northern China (''Beifang''), it lies north ...
, he developed China's own
yellow fever vaccine Yellow fever vaccine is a vaccine that protects against yellow fever. Yellow fever is a viral infection that occurs in Africa and South America. Most people begin to develop immunity within ten days of vaccination and 99 percent are protected ...
. In the mid-1950s, he first cultured the ''Chlamydia trachomatis'' agent in the yolk sacs of eggs. In 1958, the "Pulling Out Bourgeois White Flag Movement" () broke out. Tang was denounced and labeled as "capitalist academic authority", "scum of the nation", "a faithful running dog for the Kuomintang reactionaries", "American spy", "International spy", "a large white flag on the socialist positions", "ride on the backs of the people", "pseudo scientist", "sell the interests of his own country". Because of the unbearable insult he killed himself on September 30, 1958. In 1978, the Communist Party rehabilitated many victims who suffered
political persecution Political repression is the act of a state entity controlling a citizenry by force for political reasons, particularly for the purpose of restricting or preventing the citizenry's ability to take part in the political life of a society, thereby ...
or died in the mass socialism political movements except Tang Feifan. In June 1979, the Ministry of Health held a memorial service for him. In 1981, the International Organization Against Trachoma (IOAT) bestowed its gold medal upon him. He was held in high esteem by British sinologist
Joseph Needham Noel Joseph Terence Montgomery Needham (; 9 December 1900 – 24 March 1995) was a British biochemist, historian of science and sinologist known for his scientific research and writing on the history of Chinese science and technology, in ...
. On 20 November 1992,
China Post China Post, legally the China Post Group Corporation ( zh, 中国邮政集团有限公司, Pinyin: ''Zhōngguó yóuzhèng jítuán yǒuxiàn gōngsī''), is the state-owned enterprise operating the official postal service of China, which provi ...
issued a stamp commemorating Tang Feifan as part of the third set of its "Modern Chinese Scientists" stamp series (serial number 1992-19). 55 million copies were printed.


Personal life

In 1925, Tang married He Lian (), daughter of
He Jian He Jian (; 10 April 1887 – 25 April 1956) was a Chinese Nationalist (KMT) general and politician in the Republic of China. He was governor of Hunan province between 1929 and 1937, and Interior Minister from 1937 to 1939. He was best known for ...
, a warlord and governor of Hunan province.


See also

* ''
Chlamydia trachomatis ''Chlamydia trachomatis'' (), commonly known as chlamydia, is a bacterium that causes chlamydia, which can manifest in various ways, including: trachoma, lymphogranuloma venereum, nongonococcal urethritis, cervicitis, salpingitis, pelvic inflamma ...
'' *
Hundred Flowers Campaign The Hundred Flowers Campaign, also termed the Hundred Flowers Movement (), was a period from 1956 to 1957 in the People's Republic of China during which the Chinese Communist Party (CCP) encouraged citizens to openly express their opinions of t ...
*
Anti-Rightist Movement The Anti-Rightist Campaign () in the People's Republic of China, which lasted from 1957 to roughly 1959, was a political campaign to purge alleged "Rightists" within the Chinese Communist Party (CCP) and the country as a whole. The campaign was l ...
*
Cultural Revolution The Cultural Revolution, formally known as the Great Proletarian Cultural Revolution, was a sociopolitical movement in the People's Republic of China (PRC) launched by Mao Zedong in 1966, and lasting until his death in 1976. Its stated goal ...


References


External links

{{DEFAULTSORT:Tang, Feifan 1897 births 1958 suicides Biologists from Hunan Central South University alumni Chinese microbiologists Harvard University alumni Members of the Chinese Academy of Sciences Peking Union Medical College alumni People from Zhuzhou Yale School of Medicine alumni Suicides in the People's Republic of China