is a Japanese urologist and developmental biologist, known for his pioneer research on ''in vitro'' spermatogenesis. He is Professor of

Proteomics Proteomics is the large-scale study of proteins. Proteins are vital parts of living organisms, with many functions such as the formation of structural fibers of muscle tissue, enzymatic digestion of food, or synthesis and replication of DNA. In ...

at Graduate School of Medical Life Science, Yokohama City University.

Contribution

In 2011, Ogawa and his colleagues succeeded to produce functional

sperm Sperm is the male reproductive cell, or gamete, in anisogamous forms of sexual reproduction (forms in which there is a larger, female reproductive cell and a smaller, male one). Animals produce motile sperm with a tail known as a flagellum, whi ...

from spermatogonial stem cells with the testis of

mouse A mouse ( : mice) is a small rodent. Characteristically, mice are known to have a pointed snout, small rounded ears, a body-length scaly tail, and a high breeding rate. The best known mouse species is the common house mouse (''Mus musculus' ...

using an

organ culture Organ culture is a development from tissue culture methods of research, the organ culture is able to accurately model functions of an organ in various states and conditions by the use of the actual ''in vitro'' organ itself. Parts of an organ or ...

method, which was the first demonstration of mammalian. The result could change views about fertility and spermatogenesis and result in new diagnostics for male infertility as well as treatment and follow-up of patients with cancer. In 2014, his research group reported that a sample of frozen testicle has been used to produce live offspring in experiments on mice, and this breakthrough could have important implications for boys with cancer who become infertile due to chemotherapy treatments.

Biography

Ogawa received his M.D. in 1985 and his doctorate in Pathology in 1989 from Yokohama City University. After clinical residency in Urology, he worked as an urologist at several hospitals in Yokohama and neighboring cities. Wishig to study germ cells, he served as a postdoctoral fellow under Ralph L. Brinster at University of Pennsylvania between 1995 and 1998. On returning to Japan, he became a member of the faculty of Yokohama City University.

External links

Takehiko Ogawa laboratory

References

{{DEFAULTSORT:Ogawa, Takehiko Developmental biologists Japanese biologists Japanese urologists Yokohama City University alumni Academic staff of Yokohama City University Living people Year of birth missing (living people)