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Baron was a Japanese naval
physician A physician (American English), medical practitioner (Commonwealth English), medical doctor, or simply doctor, is a health professional who practices medicine, which is concerned with promoting, maintaining or restoring health through th ...
.


Early life

Born in
Hyūga Province was an old province of Japan on the east coast of Kyūshū, corresponding to the modern Miyazaki Prefecture. Nussbaum, Louis-Frédéric. (2005). "''Hyūga''" in . It was sometimes called or . Hyūga bordered on Bungo, Higo, Ōsumi, and Sats ...
(present-day
Miyazaki Prefecture is a prefecture of Japan located on the island of Kyūshū. Miyazaki Prefecture has a population of 1,073,054 (1 June 2019) and has a geographic area of 7,735 km2 (2,986 sq mi). Miyazaki Prefecture borders Ōita Prefecture to the north, Kuma ...
) as the son of a ''
samurai were the hereditary military nobility and officer caste of medieval and early-modern Japan from the late 12th century until their abolition in 1876. They were the well-paid retainers of the '' daimyo'' (the great feudal landholders). They h ...
'' retainer to the
Satsuma Satsuma may refer to: * Satsuma (fruit), a citrus fruit * ''Satsuma'' (gastropod), a genus of land snails Places Japan * Satsuma, Kagoshima, a Japanese town * Satsuma District, Kagoshima, a district in Kagoshima Prefecture * Satsuma Domain, a sou ...
domain, Takaki studied
Chinese medicine Traditional Chinese medicine (TCM) is an alternative medical practice drawn from traditional medicine in China. It has been described as "fraught with pseudoscience", with the majority of its treatments having no logical mechanism of action ...
as a youth and served as a medic in the
Boshin War The , sometimes known as the Japanese Revolution or Japanese Civil War, was a civil war in Japan fought from 1868 to 1869 between forces of the ruling Tokugawa shogunate and a clique seeking to seize political power in the name of the Imperi ...
. He later studied western medical science under British doctor William Willis (in Japan 1861–1881). Takaki entered the
Imperial Japanese Navy The Imperial Japanese Navy (IJN; Kyūjitai: Shinjitai: ' 'Navy of the Greater Japanese Empire', or ''Nippon Kaigun'', 'Japanese Navy') was the navy of the Empire of Japan from 1868 to 1945, when it was dissolved following Japan's surrender ...
as a medical officer in 1872. He was sent to
Great Britain Great Britain is an island in the North Atlantic Ocean off the northwest coast of continental Europe. With an area of , it is the largest of the British Isles, the largest European island and the ninth-largest island in the world. It is ...
for medical studies in 1875, and interned at
St Thomas's Hospital Medical School St Thomas's Hospital Medical School in London was one of the oldest and most prestigious medical schools in the UK. The school was absorbed to form part of King's College London. History It was part of one of the oldest hospitals in London, ...
now part of
King's College London King's College London (informally King's or KCL) is a public research university located in London, England. King's was established by royal charter in 1829 under the patronage of King George IV and the Duke of Wellington. In 1836, King's ...
in
London London is the capital and largest city of England and the United Kingdom, with a population of just under 9 million. It stands on the River Thames in south-east England at the head of a estuary down to the North Sea, and has been a majo ...
. He returned to Japan in 1880.


Work on beriberi

At the time,
beriberi Thiamine deficiency is a medical condition of low levels of thiamine (Vitamin B1). A severe and chronic form is known as beriberi. The two main types in adults are wet beriberi and dry beriberi. Wet beriberi affects the cardiovascular system, r ...
(considered endemic to Japan) was a serious problem on warships and was affecting naval efficiency. Takaki knew that beriberi was not common among
Western Western may refer to: Places *Western, Nebraska, a village in the US *Western, New York, a town in the US *Western Creek, Tasmania, a locality in Australia *Western Junction, Tasmania, a locality in Australia *Western world, countries that id ...
navies. He also noticed that Japanese naval officers, whose diet consisted of various types of vegetables and meat, rarely suffered from beriberi. On the other hand, the disease was common among ordinary crewmen, whose diet consisted almost exclusively of white
rice Rice is the seed of the grass species ''Oryza sativa'' (Asian rice) or less commonly ''Oryza glaberrima ''Oryza glaberrima'', commonly known as African rice, is one of the two domesticated rice species. It was first domesticated and grown i ...
(which was supplied free, whereas other foods had to be purchased). Many crewmen from poor families, who had to send money back home, often tried to save money by eating nothing but rice. In 1883 Takaki learned of a very high incidence of beriberi among cadets on a training mission from Japan to Hawaii, via New Zealand and South America that lasted for 9 months. On board, 169 men out of 376 developed the disease and 25 died. Takaki made a petition to
Emperor Meiji , also called or , was the 122nd emperor of Japan according to the traditional order of succession. Reigning from 13 February 1867 to his death, he was the first monarch of the Empire of Japan and presided over the Meiji era. He was the figur ...
to fund an experiment with an improved diet for the seamen that included more barley, meat, milk, bread and vegetables. He succeeded, and in 1884, another mission took the same route, but this time only sixteen beriberi cases among 333 seamen were reported. This experiment convinced the Imperial Japanese Navy that poor diet was the prime factor in beriberi, and the disease was soon eliminated from the fleet. Takaki's success occurred ten years before
Christiaan Eijkman Christiaan Eijkman ( , , ; 11 August 1858 – 5 November 1930) was a Dutch physician and professor of physiology whose demonstration that beriberi is caused by poor diet led to the discovery of antineuritic vitamins (thiamine). Together with S ...
, working in
Batavia Batavia may refer to: Historical places * Batavia (region), a land inhabited by the Batavian people during the Roman Empire, today part of the Netherlands * Batavia, Dutch East Indies, present-day Jakarta, the former capital of the Dutch East In ...
, advanced his theory that beriberi was caused by a
nutritional deficiency Malnutrition occurs when an organism gets too few or too many nutrients, resulting in health problems. Specifically, it is "a deficiency, excess, or imbalance of energy, protein and other nutrients" which adversely affects the body's tissues a ...
, with his later identification of vitamin B1 earning him the 1929
Nobel Prize in Physiology or Medicine The Nobel Prize in Physiology or Medicine is awarded yearly by the Nobel Assembly at the Karolinska Institute for outstanding discoveries in physiology or medicine. The Nobel Prize is not a single prize, but five separate prizes that, accord ...
. Although Takaki clearly established that the cause was due to
nutrition Nutrition is the biochemical and physiological process by which an organism uses food to support its life. It provides organisms with nutrients, which can be metabolized to create energy and chemical structures. Failure to obtain sufficient n ...
al issues, this conflicted with the prevailing idea among medical scientists that beriberi was an
infectious disease An infection is the invasion of tissues by pathogens, their multiplication, and the reaction of host tissues to the infectious agent and the toxins they produce. An infectious disease, also known as a transmissible disease or communicable dise ...
. The
Imperial Japanese Army The was the official ground-based armed force of the Empire of Japan from 1868 to 1945. It was controlled by the Imperial Japanese Army General Staff Office and the Ministry of the Army, both of which were nominally subordinate to the Emperor o ...
, which was dominated by doctors from
Tokyo Imperial University , abbreviated as or UTokyo, is a public research university located in Bunkyō, Tokyo, Japan. Established in 1877, the university was the first Imperial University and is currently a Top Type university of the Top Global University Project by ...
, persisted in their belief that beriberi was an infectious disease, and refused to implement a remedy for decades. In the
Russo-Japanese War The Russo-Japanese War ( ja, 日露戦争, Nichiro sensō, Japanese-Russian War; russian: Ру́сско-япóнская войнá, Rússko-yapónskaya voyná) was fought between the Empire of Japan and the Russian Empire during 1904 and 1 ...
of 1904–1905, over 200,000 soldiers suffered from beriberi – 27,000 fatally, compared to 47,000 deaths from
combat Combat ( French for ''fight'') is a purposeful violent conflict meant to physically harm or kill the opposition. Combat may be armed (using weapons) or unarmed ( not using weapons). Combat is sometimes resorted to as a method of self-defense, or ...
. In 1905, Takaki was ennobled with the title of ''danshaku'' (
baron Baron is a rank of nobility or title of honour, often hereditary, in various European countries, either current or historical. The female equivalent is baroness. Typically, the title denotes an aristocrat who ranks higher than a lord or knig ...
) under the ''
kazoku The was the hereditary peerage of the Empire of Japan, which existed between 1869 and 1947. They succeeded the feudal lords () and court nobles (), but were abolished with the 1947 constitution. Kazoku ( 華族) should not be confused with ' ...
'' peerage system for his contribution of eliminating beriberi from the Imperial Japanese Navy, and also awarded the
Order of the Rising Sun The is a Japanese order, established in 1875 by Emperor Meiji. The Order was the first national decoration awarded by the Japanese government, created on 10 April 1875 by decree of the Council of State. The badge features rays of sunlight ...
(first class). He was later affectionately nicknamed "Barley Baron". Takaki founded the Sei-I-Kwai medical society in January 1881. In May, 1881, he founded the Sei-I-Kwai Koshujo (Sei-I-Kwai Medical Training School), now the
Jikei University School of Medicine is a private university in Minato, Tokyo, Japan. ''Jikei'' (慈恵) means ''mercy and love'' in Japanese. Access The Nishi-Shinbashi Campus is about a 3-minute walk from Onarimon Station and about a 10-minute walk from Uchisaiwaichō Station b ...
. Takaki's school was the first private medical college in Japan, and was the first in Japan to have students dissect human cadavers. Takaki was posthumously honored by having a peninsula in
Antarctica Antarctica () is Earth's southernmost and least-populated continent. Situated almost entirely south of the Antarctic Circle and surrounded by the Southern Ocean, it contains the geographic South Pole. Antarctica is the fifth-largest contine ...
at named " Takaki Promontory" in his honor. It is the only peninsula in Antarctica named after a Japanese person.


References

* Bay, Alexander. "Beriberi in Modern Japan: The Making of a National Disease". University of Rochester Press (2012). . * Low, Morris. ''Building a Modern Japan: Science, Technology, and Medicine in the Meiji Era and Beyond''. Palgrave Macmillan (2005). . * Matsuda, Makoto. ''Kakke o nakushita otoko Takaki Kanehiro den''. Kodansha (1990). . * Kenneth J. Carpenter. ''Beriberi, White Rice and Vitamin B''. University of California Press.


External links


Jikei University School of Medicine: Our Roots - To Serve the Suffering Poor
{{DEFAULTSORT:Takaki, Kanehiro 1849 births 1920 deaths Japanese military doctors Japanese scientists People of the Boshin War People from Miyazaki Prefecture Kazoku People of Meiji-period Japan Alumni of St Thomas's Hospital Medical School University and college founders