TRNA (adenine58-N1)-methyltransferase

TRNA (adenine⁵⁸-N¹)-methyltransferase (, ''tRNA m1A58 methyltransferase'', ''tRNA (m1A58) methyltransferase'', ''TrmI'', ''tRNA (m1A58) Mtase'', ''Rv2118cp'', ''Gcd10p-Gcd14p'', ''Trm61p-Trm6p'') is an enzyme with systematic name ''S-adenosyl-L-methionine:tRNA (adenine⁵⁸-N¹)-methyltransferase''. This enzyme catalyses the following chemical reaction

: S-adenosyl-L-methionine + adenine⁵⁸ in tRNA $\rightleftharpoons$ S-adenosyl-L-homocysteine + N¹-methyladenine⁵⁸ in tRNA

The enzyme specifically methylates adenine⁵⁸ in tRNA.

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EC 2.1.1