TGBA01AD (also known as FKB01MD) is a
serotonin reuptake inhibitor,
5-HT1A and
5-HT1D receptor agonist
An agonist is a chemical that activates a receptor to produce a biological response. Receptors are cellular proteins whose activation causes the cell to modify what it is currently doing. In contrast, an antagonist blocks the action of the ago ...
, and
5-HT2 receptor antagonist
An antagonist is a character in a story who is presented as the chief foe of the protagonist.
Etymology
The English word antagonist comes from the Greek ἀνταγωνιστής – ''antagonistēs'', "opponent, competitor, villain, enemy, riv ...
which is under development by
Fabre-Kramer
Fabre-Kramer Pharmaceuticals is a pharmaceutical company that specializes in the development of psychotropic drugs. Products in their current development pipeline include gepirone and FKB01MD for major depression, gepirone and FKW00GA for general ...
for the treatment of
major depressive disorder.
It has been in
phase II Phase II, Phase 2 or Phase Two may refer to:
Media
* Marvel Cinematic Universe: Phase Two, six American superhero films from 2013–2015
* ''Star Trek: Phase II'', an unrealized television series based on the characters of Gene Roddenberry's ''S ...
clinical trials since 2009, and as of January 2016, remains in this phase of development.
See also
*
List of investigational antidepressants
References
5-HT1A agonists
5-HT1D agonists
5-HT2 antagonists
Antidepressants
Drugs with undisclosed chemical structures
Serotonin reuptake inhibitors
{{Nervous-system-drug-stub