TC OT 39 is a non-
peptide partial agonist of the
oxytocin
Oxytocin (Oxt or OT) is a peptide hormone and neuropeptide normally produced in the hypothalamus and released by the posterior pituitary. It plays a role in social bonding, reproduction, childbirth, and the period after childbirth. Oxytocin ...
and
vasopressin V2 receptors (K
i = 147 nM and >1000 nM, respectively) and
antagonist
An antagonist is a character in a story who is presented as the chief foe of the protagonist.
Etymology
The English word antagonist comes from the Greek ἀνταγωνιστής – ''antagonistēs'', "opponent, competitor, villain, enemy, riv ...
of the
vasopressin V1A receptor (K
i = 330 nM).
See also
*
WAY-267,464
WAY-267464 is a potent, selective, non-peptide agonist for the oxytocin receptor, with negligible affinity for the vasopressin receptors. Contradictorily however, though originally described as selective for the oxytocin receptor and lacking aff ...
References
Benzodiazepines
Pyrrolidines
Benzamides
Oxytocin receptor agonists
Vasopressin receptor agonists
Vasopressin receptor antagonists
Thioamides
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