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TBPO is an extremely toxic
bicyclic phosphate Bicyclic phosphate is a class of organophosphate compounds that are used as flame retardants, stabilizers and antioxidants. They are also used in spectroscopic studies. Some bicyclic phosphates, such as TBPS, TBPO and IPTBO, are highly toxic. ...
convulsant A convulsant is a drug which induces convulsions and/or epileptic seizures, the opposite of an anticonvulsant. These drugs generally act as stimulants at low doses, but are not used for this purpose due to the risk of convulsions and consequent e ...
and GABA receptor antagonist. It is the most toxic
bicyclic phosphate Bicyclic phosphate is a class of organophosphate compounds that are used as flame retardants, stabilizers and antioxidants. They are also used in spectroscopic studies. Some bicyclic phosphates, such as TBPS, TBPO and IPTBO, are highly toxic. ...
known, with an of 36 μg/kg in mice.


See also

*
TBPS TBPS (''tert''-butylbicyclophosphorothionate) is a bicyclic phosphate convulsant. It is an extremely potent GABA receptor antagonist. See also *IPTBO *EBOB EBOB is a GABA receptor antagonist and neurotoxin. See also * TBPS *IPTBO IPTBO (is ...
*
IPTBO IPTBO (isopropylbicyclophosphate, also IPPO) is a bicyclic phosphate convulsant. It is an extremely potent GABA receptor antagonist that can cause violent convulsions in mice. IPTBO is found among a group of highly toxic bicyclic phosphates. Ge ...


References

Convulsants Neurotoxins Bicyclic phosphates GABAA receptor negative allosteric modulators Tert-butyl compounds {{Neurotoxin-stub