The T7 Holin family
TC# 1.E.6 is a member of the
Holin Superfamily II The Holin superfamily II is a superfamily of putative pore-forming proteins. It is one of the seven different holin superfamilies in total. In general, these proteins are thought to play a role in regulated cell death, although functionality vari ...
. Members of this family are predominantly found in ''
Caudovirales'' and ''
Pseudomonadota
Pseudomonadota (synonym Proteobacteria) is a major phylum of Gram-negative bacteria. The renaming of phyla in 2021 remains controversial among microbiologists, many of whom continue to use the earlier names of long standing in the literature. The ...
''. They typically have only 1 transmembrane segment (TMS) and vary from 60 to 130 amino acyl residues in length. A representative list of proteins belonging to this family can be found in th
Transporter Classification Database
See also
*
Holin
*
Lysin
Lysins, also known as endolysins or murein hydrolases, are hydrolytic enzymes produced by bacteriophages in order to cleave the host's cell wall during the final stage of the lytic cycle. Lysins are highly evolved enzymes that are able to target ...
*
Transporter Classification Database
Further reading
* Hammerling, Michael J; Ellefson, Jared W; Boutz, Daniel R; Marcotte, Edward M; Ellington, Andrew D; Barrick, Jeffrey E
"Bacteriophages use an expanded genetic code on evolutionary paths to higher fitness"''Nature Chemical Biology'' 10 (3): 178–180.
doi:
10.1038/nchembio.1450.
PMC&nbs
3932624 PMID&nbs
24487692
* Lee, Jung Seok; Jang, Ho Bin; Kim, Ki Sei; Kim, Tae Hwan; Im, Se Pyeong; Kim, Si Won; Lazarte, Jassy Mary S.; Kim, Jae Sung; Jung, Tae Sung (2015-01-01)
"Complete Genomic and Lysis-Cassette Characterization of the Novel Phage, KBNP1315, which Infects Avian Pathogenic Escherichia coli (APEC)" ''PLoS ONE'' 10 (11): e0142504.
doi:
10.1371/journal.pone.0142504.
ISSN&nbs
1932-6203 PMC&nbs
4640515 PMID&nbs
26555076
* Nguyen, Huong Minh; Kang, Changwon (2014-02-01)
"Lysis delay and burst shrinkage of coliphage T7 by deletion of terminator Tφ reversed by deletion of early genes" ''Journal of Virology'' 88 (4): 2107–2115.
doi:
10.1128/JVI.03274-13.
ISSN&nbs
1098-5514 PMC&nbs
3911561 PMID&nbs
24335287
* Summer, Elizabeth J.; Enderle, Christopher J.; Ahern, Stephen J.; Gill, Jason J.; Torres, Cruz P.; Appel, David N.; Black, Mark C.; Young, Ry; Gonzalez, Carlos F. (2010-01-01)
"Genomic and biological analysis of phage Xfas53 and related prophages of Xylella fastidiosa"''Journal of Bacteriology'' 192 (1): 179–190.
doi:
10.1128/JB.01174-09.
ISSN&nbs
1098-5530 PMC&nbs
2798268 PMID&nbs
19897657
* Xu, Youqiang; Ma, Yuyue; Yao, Su; Jiang, Zengyan; Pei, Jiangsen; Cheng, Chi (2016-03-01
"Characterization, Genome Sequence, and Analysis of Escherichia Phage CICC 80001, a Bacteriophage Infecting an Efficient L-Aspartic Acid Producing Escherichia coli"''Food and Environmental Virology'' 8 (1): 18–26.
doi:
10.1007/s12560-015-9218-0.
ISSN&nbs
1867-0342 PMID&nbs
26501200
* Zhang, Xing; Studier, F. William (2004-07-16
"Multiple Roles of T7 RNA Polymerase and T7 Lysozyme During Bacteriophage T7 Infection" ''Journal of Molecular Biology'' 340 (4): 707–730.
doi:
10.1016/j.jmb.2004.05.006.
References
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Holins
Protein families