T-1194, also known as TL-1323, is an extremely toxic
carbamate nerve agent
Nerve agents, sometimes also called nerve gases, are a class of organic chemicals that disrupt the mechanisms by which nerves transfer messages to organs. The disruption is caused by the blocking of acetylcholinesterase (AChE), an enzyme that ...
.
T-1194 is the methylcarbamate ester of
edrophonium. The bromide salt of T-1194 is AR-14.
See also
*
T-1123
T-1123 is a carbamate-based acetylcholinesterase inhibitor. It was investigated as a chemical warfare agent starting in 1940. It does not go through the blood-brain barrier due to the charge on quaternary nitrogen. The antidote is atropine. T-112 ...
*
T-1152
T-1152 is a quaternary carbamate anticholinesterase. It is synthesized by reaction of m-dimethylaminophenol with methyl isocyanate, followed by quaternization with methyl iodide. Since T-1152 is toxic by ingestion, it was patented as a rodenti ...
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TL-599
*
TL-1238
TL-1238 (Substance 3393) is an extremely potent carbamate acetylcholinesterase inhibitor. It has been shown to be more potent than neostigmine.
See also
* Miotine
*Neostigmine
*T-1123
T-1123 is a carbamate-based acetylcholinesterase inhibitor ...
*
Neostigmine
Neostigmine, sold under the brand name Bloxiverz, among others, is a medication used to treat myasthenia gravis, Ogilvie syndrome, and urinary retention without the presence of a blockage. It is also used in anaesthesia to end the effects of n ...
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Miotine
Miotine is an anticholinesterase drug. Miotine was the first synthetic carbamate that was used clinically.
Unlike the miotine analog neostigmine, it doesn't have a quaternary ammonium group to give it a permanent positive charge. It can exist as ...
References
Carbamate nerve agents
Acetylcholinesterase inhibitors
Quaternary ammonium compounds
Iodides
Phenol esters
Aromatic carbamates
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