Sam Kirk (born 1981; as Samantha Kirk) is an American artist. Sam, Samuel or Samantha Kirk may also refer to:

People

* Samuel Kirk (psychologist) (1904–1996), American psychologist * Samuel Kirk (silversmith) (1793–1872), American silversmith * Tom Kirk (rugby league) (1916–1994; born Albert Samuel Kirk), Australian rugby league player * Robert Samuel Kirk, honoured at the British 2019 Birthday Honours

Fictional characters

* George Samuel Kirk, Jr. (Star Trek), older brother of James T. Kirk, known as "Sam" * George Samuel Kirk, Sr. (Star Trek), father of James T. Kirk and Sam Kirk

* Samuel Kirk & Sons; a U.S. silverware company established by Samuel Kirk (silversmith) {{hndis, Sam Kirk, Sam Kirk