Samuel David Gross
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Samuel David Gross (July 8, 1805 – May 6, 1884) was an American academic trauma surgeon. Surgeon biographer Isaac Minis Hays called Gross "The Nestor of American Surgery." He is immortalized in
Thomas Eakins Thomas Cowperthwait Eakins (; July 25, 1844 – June 25, 1916) was an American realist painter, photographer, sculptor, and fine arts educator. He is widely acknowledged to be one of the most important American artists. For the length ...
' ''
The Gross Clinic ''The Gross Clinic'' or ''The Clinic of Dr. Gross'' is an 1875 painting by American artist Thomas Eakins. It is oil on canvas and measures by . The painting depicts Dr. Samuel D. Gross, a seventy-year-old professor dressed in a black frock coat, ...
'' (1875), a prominent American painting of the nineteenth century. A bronze statue of him was cast by
Alexander Stirling Calder Alexander Stirling Calder (January 11, 1870 – January 7, 1945) was an American sculptor and teacher. He was the son of sculptor Alexander Milne Calder and the father of sculptor Alexander (Sandy) Calder. His best-known works are ''George Washi ...
and erected on the National Mall, but moved in 1970 to
Thomas Jefferson University Thomas Jefferson University is a private research university in Philadelphia, Pennsylvania. Established in its earliest form in 1824, the university officially combined with Philadelphia University in 2017. To signify its heritage, the univer ...
in
Philadelphia Philadelphia, often called Philly, is the List of municipalities in Pennsylvania#Municipalities, largest city in the Commonwealth (U.S. state), Commonwealth of Pennsylvania, the List of United States cities by population, sixth-largest city i ...
.


Early life and training

Born on a farm near
Easton, Pennsylvania Easton is a city in, and the county seat of, Northampton County, Pennsylvania, United States. The city's population was 28,127 as of the 2020 census. Easton is located at the confluence of the Lehigh River, a river that joins the Delaware R ...
, Gross developed an interest in plants, trees, and flowers. He grew up speaking Pennsylvania Dutch, a dialect of German, and supposedly resolved to be a doctor when he was only five years old. At the age of 17 he was apprenticed to a local physician, then another, but both of these experiences soon proved unsatisfactory. He then started to work under the tutelage of Dr. Joseph K. Swift, a graduate of the
University of Pennsylvania The University of Pennsylvania (also known as Penn or UPenn) is a private research university in Philadelphia. It is the fourth-oldest institution of higher education in the United States and is ranked among the highest-regarded universitie ...
. Swift realized quickly that Gross' rudimentary education was insufficient training for work as a doctor. Gross then returned to preparatory school, first attending Wilkes-Barre Academy. He went on to another school in the Bowery in New York (where he received a background in classical studies) and
Lawrenceville School The Lawrenceville School is a coeducational preparatory school for boarding and day students located in the Lawrenceville section of Lawrence Township, in Mercer County, New Jersey, United States. Lawrenceville is a member of the Eight Scho ...
in
New Jersey New Jersey is a state in the Mid-Atlantic and Northeastern regions of the United States. It is bordered on the north and east by the state of New York; on the east, southeast, and south by the Atlantic Ocean; on the west by the Delaware ...
. At 19, Gross returned to Swift's office, where he learned mineralogy,
anatomy Anatomy () is the branch of biology concerned with the study of the structure of organisms and their parts. Anatomy is a branch of natural science that deals with the structural organization of living things. It is an old science, having it ...
, surgery, Materia Medica, therapeutics,
physiology Physiology (; ) is the scientific study of functions and mechanisms in a living system. As a sub-discipline of biology, physiology focuses on how organisms, organ systems, individual organs, cells, and biomolecules carry out the chemical ...
, obstetrics, and French. He also received a fair amount of clinical experience with Swift's patients. After a year of training under Swift, he took a six-week vacation due to ill health. Swift advised him to attend the University of Pennsylvania for further training, but Gross opted for the newly founded
Jefferson Medical College Thomas Jefferson University is a private research university in Philadelphia, Pennsylvania. Established in its earliest form in 1824, the university officially combined with Philadelphia University in 2017. To signify its heritage, the unive ...
in
Philadelphia Philadelphia, often called Philly, is the List of municipalities in Pennsylvania#Municipalities, largest city in the Commonwealth (U.S. state), Commonwealth of Pennsylvania, the List of United States cities by population, sixth-largest city i ...
, as he greatly admired the founder of the school, Professor of Surgery Dr.
George McClellan George Brinton McClellan (December 3, 1826 – October 29, 1885) was an American soldier, Civil War Union general, civil engineer, railroad executive, and politician who served as the 24th governor of New Jersey. A graduate of West Point, McCl ...
, and his colleague, Dr. John Eberle, Professor of Medicine. Gross entered Jefferson in the fall of 1826 and graduated in 1828 in a class of 27 students.


Early career in Pennsylvania and Ohio

Gross began practice in an office at the corner of Fifth and Library Streets in Philadelphia. His patients were few, and he spent much of the time translating French and German medical texts into English, but this did not augment his income sufficiently. He married a twenty-year-old widow with one child, and soon moved back to Easton, where the cost of living was lower and there were greater opportunities for young physicians. He purchased a home there and built a small laboratory in the rear where he spent several hours a day on human and animal dissection. He also became interested in research on blood
coagulation Coagulation, also known as clotting, is the process by which blood changes from a liquid to a gel, forming a blood clot. It potentially results in hemostasis, the cessation of blood loss from a damaged vessel, followed by repair. The mechanis ...
, gastric and renal excretion, animal inoculation of
smallpox Smallpox was an infectious disease caused by variola virus (often called smallpox virus) which belongs to the genus Orthopoxvirus. The last naturally occurring case was diagnosed in October 1977, and the World Health Organization (WHO) c ...
, and pulmonary pathology following
strangulation Strangling is compression of the neck that may lead to unconsciousness or death by causing an increasingly hypoxic state in the brain. Fatal strangling typically occurs in cases of violence, accidents, and is one of two main ways that hangin ...
. When a cholera epidemic struck Easton, he was sent to New York by the town council in order to learn about approved treatments for the disease. Gross wanted to become a teacher of anatomy, and in 1833 he contacted John Eberle, his former professor at Jefferson and then professor of Materia Medica at the Medical College of Ohio in
Cincinnati Cincinnati ( ) is a city in the U.S. state of Ohio and the county seat of Hamilton County. Settled in 1788, the city is located at the northern side of the confluence of the Licking and Ohio rivers, the latter of which marks the state line wit ...
. Eberle was able to obtain Gross a position as demonstrator of anatomy there, and soon afterwards Gross moved to Cincinnati with his wife and two children. However, jealousy from the head of the Anatomy Department meant that he was unable to lecture in the regular amphitheater but instead was relocated to an attic space. A short time later Gross accepted a position as chief of pathological anatomy in the Medical Department of the Cincinnati College. There he met Dr.
Daniel Drake Daniel Drake (October 20, 1785 – November 5, 1852) was a pioneering American physician and prolific writer. Early life Drake was born in Plainfield, New Jersey, to Isaac Drake and Elizabeth Shotwell. He was the elder brother of Benjamin ...
, with whom he formed a close personal friendship that lasted until Drake's death in 1852.


Transfer to Louisville

In 1839, the college in Cincinnati folded. Drake had previously accepted the chair of pathological anatomy and clinical medicine at the Louisville Medical Institute, founded in 1833, and his influence caused Gross to accept a job at this school, refusing professorships from the
University of Virginia The University of Virginia (UVA) is a public research university in Charlottesville, Virginia. Founded in 1819 by Thomas Jefferson, the university is ranked among the top academic institutions in the United States, with highly selective ad ...
and the University of
Louisiana Louisiana , group=pronunciation (French: ''La Louisiane'') is a state in the Deep South and South Central regions of the United States. It is the 20th-smallest by area and the 25th most populous of the 50 U.S. states. Louisiana is borde ...
. Gross and his family took up residence at the
Louisville Louisville ( , , ) is the largest city in the Commonwealth of Kentucky and the 28th most-populous city in the United States. Louisville is the historical seat and, since 2003, the nominal seat of Jefferson County, on the Indiana border. ...
Hotel in 1840, and shortly thereafter he established an office and residence on the east side of Fifth Street between Green (now Liberty) and Walnut Streets. The 1847 city directory listed his office and house on the north side of Walnut Street between Third and Fourth. Soon after his arrival, in 1841 Gross set up a dog laboratory in the basement of the college building, which was then only two years old and described "as for beauty and convenience not surpassed by any similar edifice on the continent." $30,000 had been spent on the structure and $20,000 for the purchase of books, chemical apparatus and anatomical preparations in Europe by Dr. Joshua Flint, Gross' predecessor as Professor of Surgery. Lectures at the college began the first Monday in November and lasted until March. Dissecting rooms were opened the first of October to purchasers of advance tickets. Students were also freely admitted to the wards of the Louisville Marine Hospital, in existence from 1823. Gross also entered into private practice, which he conducted at St. Joseph Hospital, opened 20 November 1836 as St. Vincent's Infirmary and housed in an eponymous orphanage on Jefferson Street. In 1853, it moved to a rented building on the west side of Fourth Street between Chestnut and Broadway. He remained in Louisville for sixteen years, except for a year spent on the faculty of the University of the City of New York. With Drake and his colleagues, Gross helped make the Louisville Medical Institute the most important medical center in the western United States. During Gross's time there, the institution attained a reputation equal to similar ones east of the
Appalachian Mountains The Appalachian Mountains, often called the Appalachians, (french: Appalaches), are a system of mountains in eastern to northeastern North America. The Appalachians first formed roughly 480 million years ago during the Ordovician Period. They ...
, and at the time of Gross's hiring, his fellow professors at Louisville had all attained national if not international fame in their respective fields. Gross's tenure in Louisville, however, was not without controversy. His predecessor, Joshua Flint, had become famous as a surgeon in
New England New England is a region comprising six states in the Northeastern United States: Connecticut, Maine, Massachusetts, New Hampshire, Rhode Island, and Vermont. It is bordered by the state of New York (state), New York to the west and by the Can ...
before coming to Louisville, and in 1850 Flint accepted a position as chief of surgery in the newly organized Kentucky School of Medicine, a move which began a bitter rivalry between that institution and the Louisville Medical Institute until the two schools were merged in 1908. Gross became very popular in social circles, however. He and his family were close friends with the Crittendens, Breckenridges, Wooleys, Prestons, Wickliffes, Pirtles, Ballards, Rowans, Guthries, and Prentices. Gross had even been a guest of Henry Clay at his estate, " Ashland," in Lexington. He was a member of the Unitarian Church and the St. George Lodge of Masons. In 1854, he also became a member of the
American Philosophical Society The American Philosophical Society (APS), founded in 1743 in Philadelphia, is a scholarly organization that promotes knowledge in the sciences and humanities through research, professional meetings, publications, library resources, and communit ...
. In August 1855, Gross, a close friend of
John Barbee John Barbee (September 16, 1815 – December 22, 1888) was the tenth Mayor of Louisville, Kentucky from 1855 to 1857 and chiefly remembered for his part in the anti-immigrant riots known as "Bloody Monday". Life He was born in Pewee Valley, Ke ...
, the Mayor of Louisville, helped save the Catholic
Cathedral A cathedral is a church that contains the '' cathedra'' () of a bishop, thus serving as the central church of a diocese, conference, or episcopate. Churches with the function of "cathedral" are usually specific to those Christian denominatio ...
on Fifth Street from an anti-foreign
Know-Nothing Party The Know Nothing party was a nativist political party and movement in the United States in the mid-1850s. The party was officially known as the "Native American Party" prior to 1855 and thereafter, it was simply known as the "American Party". ...
mob that intended to burn it down in what was known as the
Bloody Monday Bloody Monday was a series of riots on August 6, 1855, in Louisville, Kentucky, an election day, when Protestant mobs attacked Irish and German Catholic neighborhoods. These riots grew out of the bitter rivalry between the Democrats and the Nat ...
riot.


Return to Philadelphia

In 1856, Gross's alma mater, Jefferson Medical College, offered him a position as professor of surgery, and he accepted it despite having turned down a similar position from the University of Pennsylvania the previous year. Before he left for Philadelphia, however, the citizens of Louisville honored him with a grand ball at the Galt House. During the
Civil War A civil war or intrastate war is a war between organized groups within the same state (or country). The aim of one side may be to take control of the country or a region, to achieve independence for a region, or to change government policies ...
, Gross served as a surgical consultant for the
U.S. Surgeon General The surgeon general of the United States is the operational head of the United States Public Health Service Commissioned Corps (PHSCC) and thus the leading spokesperson on matters of public health in the federal government of the United States. Th ...
, and prepared a small handbook on military medicine. In Philadelphia Gross became one of the most prominent members of several medical organizations as physicians in the United States increasingly sought to professionalize their vocation. He served as the twentieth president of the
American Medical Association The American Medical Association (AMA) is a professional association and lobbying group of physicians and medical students. Founded in 1847, it is headquartered in Chicago, Illinois. Membership was approximately 240,000 in 2016. The AMA's sta ...
(AMA), and delivered the presidential address at the 1868 session, where the first item on the agenda was to more efficiently publish and create a more scholarly and scientific focus for the ''Transactions of the American Medical Association'', the forerunner of the '' Journal of the American Medical Association''. During his time in Philadelphia Gross also helped found the
American Surgical Association The American Surgical Association is the oldest surgical organization in the United States. History It was founded in 1880. Their publication, ''Annals of Surgery'', was started in 1885. A collection of the association's papers are held at the Nat ...
and the Philadelphia Pathological Association. Earlier in Kentucky he had founded, with T.G. Richardson, the ''Louisville Medical Review'' and the ''North American Chirurgical Review''. In 1875 Gross returned to Louisville for a meeting of the AMA, where he was re-elected president and entertained lavishly, even being presented by the physicians of Kentucky with two
thoroughbred The Thoroughbred is a horse breed best known for its use in horse racing. Although the word ''thoroughbred'' is sometimes used to refer to any breed of purebred horse, it technically refers only to the Thoroughbred breed. Thoroughbreds are ...
horses. He made his final visit to Kentucky two years later, in 1877, when he gave a memorial oration in honor of the famous surgeon
Ephraim McDowell Ephraim McDowell (November 11, 1771 – June 25, 1830) was an American physician and pioneer surgeon. The first person to successfully remove an ovarian tumor, he has been called "the father of ovariotomy" as well as founding father of abdomina ...
in Danville. Gross was presented with the original door knocker from McDowell's home; for a time the gift resided in the collection of the Museum of the
College of Physicians A college of physicians is a national or provincial organisation concerned with the practice of medicine. {{Expand list, date=February 2011 Such institutions include: * American College of Physicians * Ceylon College of Physicians * College of Phy ...
in Philadelphia, but has since been returned to the McDowell house in Danville, where it is kept under glass.


''The Gross Clinic''

Also in 1875, Gross was depicted by artist
Thomas Eakins Thomas Cowperthwait Eakins (; July 25, 1844 – June 25, 1916) was an American realist painter, photographer, sculptor, and fine arts educator. He is widely acknowledged to be one of the most important American artists. For the length ...
in his celebrated painting ''The Gross Clinic'', which Eakins showed at the 1876
Centennial Exposition The Centennial International Exhibition of 1876, the first official World's Fair to be held in the United States, was held in Philadelphia, Pennsylvania, from May 10 to November 10, 1876, to celebrate the 100th anniversary of the signing of the ...
in Philadelphia. However, the graphic nature of the painting led the judges in the artistic section to banish it to the section on medical displays. The painting lionizes Gross at the peak of his career, skillfully performing the removal of a malignancy in the thigh of a young patient while explaining the surgical techniques to a captivated audience of students in the medical amphitheater at Jefferson Medical College. Thus Eakins depicted Gross as a titan in his dual capacities as both physician and teacher. The painting is now considered one of the greatest works of nineteenth century American art. The painting clearly shows that Dr. Gross was not convinced of the efficacy of
antisepsis An antiseptic (from Greek ἀντί ''anti'', "against" and σηπτικός ''sēptikos'', "putrefactive") is an antimicrobial substance or compound that is applied to living tissue/skin to reduce the possibility of infection, sepsis, or putr ...
, despite the recent work of
Joseph Lister Joseph Lister, 1st Baron Lister, (5 April 182710 February 1912) was a British surgeon, medical scientist, experimental pathologist and a pioneer of antiseptic surgery and preventative medicine. Joseph Lister revolutionised the craft of ...
and Louis Pasteur demonstrating the germ theory to explain infections. All participants and onlookers of the depicted surgery in the painting wear normal clothing, not sterilized surgical gowns; there is no sign of gloves or surgical masks; and the presumption is that none of the instruments or hands were sterilized before surgery. Dr. Gross is quoted as saying: "Little if any faith is placed by any enlightened or experienced surgeon on this side of the Atlantic in the so-called carbolic acid treatment of Professor Lister". In contrast, we see in Eakins' later painting, ''The Agnew Clinic'', a move towards sterility in the surgical theater. Fourteen years later, Eakins produced a similar painting, '' The Agnew Clinic'' (1889), depicting Gross's counterpart, David Hayes Agnew, performing surgery in the amphitheater at the University of Pennsylvania. ''The Agnew Clinic'' is now on loan to the Philadelphia Museum of Art, which also shares ownership of ''The Gross Clinic'' with the
Pennsylvania Academy of the Fine Arts The Pennsylvania Academy of the Fine Arts (PAFA) is a museum and private art school in Philadelphia, Pennsylvania.
. Thomas Jefferson University sold the latter painting in late 2006.


Death

Gross died on May 6, 1884, at age 78, in Philadelphia. He was cremated at Le Moyne Crematory and his ashes were buried in
The Woodlands Cemetery The Woodlands is a National Historic Landmark District on the west bank of the Schuylkill River in Philadelphia. It includes a Federal-style mansion, a matching carriage house and stable, and a garden landscape that in 1840 was transformed into ...
. Gross' estate, aside from a few bequests, was divided equally among his four children. His library, consisting of more than 5,000 volumes, was willed to the Philadelphia Academy of Surgery, along with his wet preparations, diagrams, and museum. To the same institution he left $5,000; interest on this sum is awarded every five years to the best essay on surgical pathology.


Honors

Gross received many posthumous accolades. A bronze statue was dedicated by president
William McKinley William McKinley (January 29, 1843September 14, 1901) was the 25th president of the United States, serving from 1897 until his assassination in 1901. As a politician he led a realignment that made his Republican Party largely dominant in ...
, in the Smithsonian Park of the
U.S. Capitol The United States Capitol, often called The Capitol or the Capitol Building, is the seat of the legislative branch of the United States federal government, which is formally known as the United States Congress. It is located on Capitol Hill at ...
on a pedestal appropriated by the
U.S. Congress The United States Congress is the legislature of the federal government of the United States. It is bicameral, composed of a lower body, the House of Representatives, and an upper body, the Senate. It meets in the U.S. Capitol in Washin ...
. In 1970 it was relocated to the campus of
Thomas Jefferson University Thomas Jefferson University is a private research university in Philadelphia, Pennsylvania. Established in its earliest form in 1824, the university officially combined with Philadelphia University in 2017. To signify its heritage, the univer ...
in
Center City Philadelphia Center City includes the central business district and central neighborhoods of Philadelphia. It comprises the area that made up the City of Philadelphia prior to the Act of Consolidation, 1854, which extended the city borders to be coterminous wi ...
.Samuel D. Gross
Campus Art at Thomas Jefferson University
In Louisville a portrait of him hangs in the Fred Rankin Amphitheater, and since 1941, the
Phi Delta Epsilon Phi Delta Epsilon () (commonly known as PhiDE) is a co-ed international medical fraternity and a member of the Professional Fraternity Association. History Phi Delta Epsilon was founded on October 13, 1904, at Cornell University Medical College. ...
Medical Fraternity has sponsored an annual Samuel D. Gross lectureship.


Writings

After Gross moved to Cincinnati, he ceased his translation work and began to publish original contributions to the scientific field. In 1839, Gross published ''Elements of Pathological Anatomy'', the first systematic treatise on the subject in the United States; its two volumes were lavishly illustrated with woodcuts and colored engravings. The second edition received praise form the eminent German scientist
Rudolf Virchow Rudolf Ludwig Carl Virchow (; or ; 13 October 18215 September 1902) was a German physician, anthropologist, pathologist, prehistorian, biologist, writer, editor, and politician. He is known as "the father of modern pathology" and as the founder ...
. Gross's 1859 two-volume ''System of Surgery'' is perhaps his best known work. His other publications include: * ''The Anatomy, Physiology, and Diseases of the Bones and Joints'' (1830) * ''An Experimental and Critical Inquiry into the Nature and Treatment of Wounds of the Intestines'' (1843) * ''A Practical Treatise on the Diseases, Injuries, and Malformations of the Urinary
Bladder The urinary bladder, or simply bladder, is a hollow organ in humans and other vertebrates that stores urine from the kidneys before disposal by urination. In humans the bladder is a distensible organ that sits on the pelvic floor. Urine enters ...
, the
Prostate Gland The prostate is both an accessory gland of the male reproductive system and a muscle-driven mechanical switch between urination and ejaculation. It is found only in some mammals. It differs between species anatomically, chemically, and physio ...
, and the
Urethra The urethra (from Greek οὐρήθρα – ''ourḗthrā'') is a tube that connects the urinary bladder to the urinary meatus for the removal of urine from the body of both females and males. In human females and other primates, the urethra c ...
'' (1851)
''A Practical Treatise on Foreign Bodies in the Air-Passages'' (1854)
Gross was also interested in history, as he published several medical biographies and wrote on the history of
Kentucky Kentucky ( , ), officially the Commonwealth of Kentucky, is a state in the Southeastern region of the United States and one of the states of the Upper South. It borders Illinois, Indiana, and Ohio to the north; West Virginia and Virginia ...
. In 1861 he edited ''The Lives of Eminent American Physicians and Surgeons of the Nineteenth Century'', and once gave a talk to the Kentucky State Medical Association wherein he resurrected the career of the early Kentucky physician Dr.
Ephraim McDowell Ephraim McDowell (November 11, 1771 – June 25, 1830) was an American physician and pioneer surgeon. The first person to successfully remove an ovarian tumor, he has been called "the father of ovariotomy" as well as founding father of abdomina ...
. Early in the nineteenth century McDowell had removed a
urinary stone A bladder stone is a stone found in the urinary bladder. Signs and symptoms Bladder stones are small mineral deposits that can form in the bladder. In most cases bladder stones develop when the urine becomes very concentrated or when one is d ...
from a young
James K. Polk James Knox Polk (November 2, 1795 – June 15, 1849) was the 11th president of the United States, serving from 1845 to 1849. He previously was the 13th speaker of the House of Representatives (1835–1839) and ninth governor of Tennessee (183 ...
, and distinguished himself as one of the most capable surgeons in America and the originator of abdominal surgery, as well as being the first ovariotomist.


References


Bibliography

* * * * * * * * * * * * * * * * * *Wagner FB Jr, Savacool JW, eds. ''Jefferson Medical College of Thomas Jefferson University: Legend & Lore''. Devon, PA: W.T. Cooke Pub., 1996.


External links


10 Notable Jefferson Alumni, Samuel D. GrossSamuel David Gross: Address by John Chalmers Da Costa, M.D., L.L.D.Samuel David Gross: The Lesson of His Life and Labors, by William Williams Keen, M.D.A Manual of Military Surgery, by S.D. Gross, M.D., 1861
*
Complete bibliography of the works by Samuel Gross
compiled by Samuel A. Davis, Thomas Jefferson University, 1991. {{DEFAULTSORT:Gross, Samuel 1805 births 1884 deaths Physicians from Philadelphia Thomas Jefferson University alumni Thomas Jefferson University faculty Lawrenceville School alumni People from Easton, Pennsylvania American Surgical Association members Burials at The Woodlands Cemetery 19th-century American people University of Louisville faculty Presidents of the American Medical Association