Proton-coupled amino acid transporter 2 is a
protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, respo ...
which in humans is encoded by the ''SLC36A2''
gene
In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a ba ...
.
Function
SLC36A2 transports small amino acids (glycine, alanine, and proline) and also the D-enantiomers and select amino acid derivatives, such as gamma-aminobutyric acid.
Clinical significance
Mutations in the SLC36A2 gene are associated with
Iminoglycinuria.
See also
*
Proton coupled amino acid transporter Proton-coupled amino acid transporters belong to the SLC26A5 family; they are protein receptors whose main function is the transmembrane
A transmembrane protein (TP) is a type of integral membrane protein that spans the entirety of the cell mem ...
References
Further reading
*
*
*
*
*
*
Solute carrier family
{{gene-5-stub