Syndromic Keratoderma
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Keratoderma is a hornlike skin condition.WordNet Search - 3.0
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Classification

The keratodermas are classified into the following subgroups:Freedberg, et al. (2003). ''Fitzpatrick's Dermatology in General Medicine''. (6th ed.). McGraw-Hill. .


Congenital

* Simple keratodermas **
Diffuse palmoplantar keratoderma Palmoplantar keratodermas are a heterogeneous group of disorders characterized by abnormal thickening of the stratum corneum of the palms and soles. Autosomal recessive, dominant trait, dominant, X-linked, and acquired forms have all been describe ...
s ***
Diffuse epidermolytic palmoplantar keratoderma Palmoplantar keratodermas are a heterogeneous group of disorders characterized by abnormal thickening of the stratum corneum of the palms and soles. Autosomal recessive, dominant, X-linked, and acquired forms have all been described. Types Cli ...
***
Diffuse nonepidermolytic palmoplantar keratoderma Palmoplantar keratodermas are a heterogeneous group of disorders characterized by abnormal thickening of the stratum corneum of the palms and soles. Autosomal recessive, dominant, X-linked, and acquired forms have all been described. Types C ...
*** mal de Meleda ** Focal palmoplantar keratoderma *** Striate palmoplantar keratoderma **
Punctate palmoplantar keratoderma Palmoplantar keratodermas are a heterogeneous group of disorders characterized by abnormal thickening of the stratum corneum of the palms and soles. Autosomal recessive, dominant, X-linked, and acquired forms have all been described. Types Cli ...
***
Keratosis punctata palmaris et plantaris Palmoplantar keratodermas are a heterogeneous group of disorders characterized by abnormal thickening of the stratum corneum of the palms and soles. Autosomal recessive, dominant, X-linked, and acquired forms have all been described. Types Cli ...
***
Spiny keratoderma Palmoplantar keratodermas are a heterogeneous group of disorders characterized by abnormal thickening of the stratum corneum of the palms and soles. Autosomal recessive, dominant, X-linked, and acquired forms have all been described. Types Cli ...
***
Focal acral hyperkeratosis Palmoplantar keratodermas are a heterogeneous group of disorders characterized by abnormal thickening of the stratum corneum of the palms and soles. Autosomal recessive, dominant, X-linked, and acquired forms have all been described. Types Cli ...
* Complex keratodermas **
Diffuse palmoplantar keratoderma Palmoplantar keratodermas are a heterogeneous group of disorders characterized by abnormal thickening of the stratum corneum of the palms and soles. Autosomal recessive, dominant trait, dominant, X-linked, and acquired forms have all been describe ...
***
Erythrokeratodermia variabilis Erythrokeratodermia variabilis (also known as "erythrokeratodermia figurata variabilis", "keratosis extremitatum progrediens", "keratosis palmoplantaris transgrediens et progrediens",Freedberg, et al. (2003). ''Fitzpatrick's Dermatology in General ...
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Palmoplantar keratoderma of Sybert Palmoplantar keratodermas are a heterogeneous group of disorders characterized by abnormal thickening of the stratum corneum of the palms and soles. Autosomal recessive, dominant, X-linked, and acquired forms have all been described. Types Cli ...
***
Olmsted syndrome Palmoplantar keratodermas are a heterogeneous group of disorders characterized by abnormal thickening of the stratum corneum of the palms and soles. Autosomal recessive, dominant, X-linked, and acquired forms have all been described. Types Cli ...
***
Naegeli–Franceschetti–Jadassohn syndrome Naegeli–Franceschetti–Jadassohn syndrome (NFJS), also known as chromatophore nevus of Naegeli and Naegeli syndrome, is a rare autosomal dominant form of ectodermal dysplasia, characterized by reticular skin pigmentation, diminished function of ...
** Focal palmoplantar keratoderma *** Papillon–Lefèvre syndrome *** Pachyonychia congenita type I ***
Pachyonychia congenita type II Pachyonychia congenita (often abbreviated as "PC") is a rare group of autosomal dominant skin disorders that are caused by a mutation in one of five different keratin genes. Pachyonychia congenita is often associated with thickened toenails, plant ...
***
Focal palmoplantar keratoderma with oral mucosal hyperkeratosis Palmoplantar keratodermas are a heterogeneous group of disorders characterized by abnormal thickening of the stratum corneum of the palms and soles. Autosomal recessive, dominant, X-linked, and acquired forms have all been described. Types Cli ...
*** Camisa disease **
Ectodermal dysplasia Ectodermal dysplasia (ED) is a group of genetic syndromes all deriving from abnormalities of the ectodermal structures.James, William; Berger, Timothy; Elston, Dirk (2005). ''Andrews' Diseases of the Skin: Clinical Dermatology''. (10th ed.). Sau ...
s ***
Clouston's hidrotic ectodermal dysplasia Clouston's hidrotic ectodermal dysplasia is a medical condition caused by mutations in a connexin gene, GJB6 or connexin-30, characterized by scalp hair that is wiry, brittle, and pale, often associated with patchy alopecia.Freedberg, et al. (20 ...
*** Acrokeratotic poikiloderma *** Dermatopathic pigmentosa reticularis ** Syndromic keratodermas ***
Vohwinkel syndrome Palmoplantar keratodermas are a heterogeneous group of disorders characterized by abnormal thickening of the stratum corneum of the palms and soles. Autosomal recessive, dominant, X-linked, and acquired forms have all been described. Types Cli ...
*** Palmoplantar keratoderma associated with esophageal cancer ***
Palmoplantar keratoderma and spastic paraplegia Palmoplantar keratodermas are a heterogeneous group of disorders characterized by abnormal thickening of the stratum corneum of the palms and soles. Autosomal recessive, dominant, X-linked, and acquired forms have all been described. Types Cli ...
***
Naxos disease __notoc__ Naxos disease (also known as "diffuse non-epidermolytic palmoplantar keratoderma with woolly hair and cardiomyopathy" or "diffuse palmoplantar keratoderma with woolly hair and arrhythmogenic right ventricular cardiomyopathy", first desc ...
***
Striate palmoplantar keratoderma, woolly hair, and left ventricular dilated cardiomyopathy Palmoplantar keratodermas are a heterogeneous group of disorders characterized by abnormal thickening of the stratum corneum of the palms and soles. Autosomal recessive, dominant, X-linked, and acquired forms have all been described. Types Cli ...
*** Keratitis-ichthyosis-deafness syndrome *** Corneodermatosseous syndrome *** Huriez syndrome *** Oculocutaneous tyrosinemia *** Cardiofaciocutaneous syndrome ***
Schöpf–Schulz–Passarge syndrome Schöpf–Schulz–Passarge syndrome is an autosomal recessive condition with punctate symmetric palmoplantar keratoderma, with the keratoderma and fragility of the nails beginning around age 12.Freedberg, et al. (2003). ''Fitzpatrick's Dermatolo ...


Acquired

* Acquired keratodermas ** AIDS-associated keratoderma ** Arsenical keratoses **
Calluses A callus is an area of thickened and sometimes hardened skin that forms as a response to repeated friction, pressure, or other irritation. Since repeated contact is required, calluses are most often found on the feet and hands, but they may o ...
** Climacteric keratoderma **
Clavi Clavus may refer to: * Claudius Clavus (born 1388), 15th-century Danish cartographer * ''Clavus'' (gastropod), a genus of snails in the family Drilliidae * The Roman ''clavus'', a reddish-purple stripe on garments that distinguished members of th ...
(Corns) **
Eczema Dermatitis is inflammation of the Human skin, skin, typically characterized by itchiness, erythema, redness and a rash. In cases of short duration, there may be small blisters, while in long-term cases the skin may become lichenification, thick ...
**
Human papillomavirus Human papillomavirus infection (HPV infection) is caused by a DNA virus from the ''Papillomaviridae'' family. Many HPV infections cause no symptoms and 90% resolve spontaneously within two years. In some cases, an HPV infection persists and res ...
** Keratoderma blenorrhagicum ** Lichen planus ** Norwegian scabies ** Paraneoplastic keratoderma **
Psoriasis Psoriasis is a long-lasting, noncontagious autoimmune disease characterized by raised areas of abnormal skin. These areas are red, pink, or purple, dry, itchy, and scaly. Psoriasis varies in severity from small, localized patches to complete ...
**
Reactive arthritis Reactive arthritis, also known as Reiter's syndrome, is a form of inflammatory arthritis that develops in response to an infection in another part of the body (cross-reactivity). Coming into contact with bacteria and developing an infection can ...
** Secondary syphilis **
Tinea pedis Dermatophytosis, also known as ringworm, is a fungal infection of the skin. Typically it results in a red, itchy, scaly, circular rash. Hair loss may occur in the area affected. Symptoms begin four to fourteen days after exposure. Multiple ar ...
** Sézary syndrome **
Tuberculosis verrucosa cutis Tuberculosis verrucosa cutis is a rash of small, red papular nodules in the skin that may appear 2–4 weeks after inoculation by ''Mycobacterium tuberculosis'' in a previously infected and immunocompetent individual. It is also known as "prosecto ...
** Drug-induced keratoderma


Treatment

Keratolytic products containing, urea, salicylic, glycolic and lactic acids are helpful. One proprietary cream (Pedifix Cracks and Calluses Cream) is efficacious.


See also

*
Palmoplantar keratoderma Palmoplantar keratodermas are a heterogeneous group of disorders characterized by abnormal thickening of the stratum corneum of the palms and soles. Autosomal recessive, dominant, X-linked, and acquired forms have all been described. Types Cli ...
* Skin lesion *
List of cutaneous conditions Many skin conditions affect the human integumentary system—the organ system covering the entire surface of the body and composed of skin, hair, nails, and related muscle and glands. The major function of this system is as a barrier against t ...
* List of conditions caused by problems with junctional proteins


References


External links

Papulosquamous hyperkeratotic cutaneous conditions {{Cutaneous-condition-stub