Susan Quaggin
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Susan E. Quaggin is a Canadian nephrologist. She is the Charles Horace Mayo Professor of Medicine at Northwestern University Feinberg School of Medicine, Director of the Feinberg Cardiovascular Research Institute, prior chief of the Division of Nephrology, now Chair of the Department of Medicine.


Early life and education

Quaggin attended
Branksome Hall Branksome Hall is an independent day and boarding school for girls in Toronto, Ontario, Canada. It is an International Baccalaureate (IB) World School and a university-preparatory school. All three IB programs are offered: the Primary Years Pro ...
, where she met her future husband Kevin Smith who attended
Royal St. George's College Royal St. George's College (RSGC) is an independent school for boys located in The Annex neighbourhood of Toronto, Ontario, Canada. The school admits boys from Grades 3 through 12. Founded in 1961 as an Anglican choir school in the tradition of t ...
. She attended the
University of Toronto Faculty of Medicine The Temerty Faculty of Medicine (previously Faculty of Medicine) is the medical school of the University of Toronto. Founded in 1843, the faculty is based in Downtown Toronto and is one of Canada's oldest institutions of medical studies, being k ...
, where she received the Carl W. Gottschalk Research Scholar Award from the
American Society of Nephrology Founded in 1966, the American Society of Nephrology (ASN) is the world's largest professional society devoted to the study of kidney disease. Composed of over 20,000 physicians and scientists, ASN promotes expert patient care, advances medical r ...
, and completed her post-doctoral fellowship at the
Yale School of Medicine The Yale School of Medicine is the graduate medical school at Yale University, a private research university in New Haven, Connecticut. It was founded in 1810 as the Medical Institution of Yale College and formally opened in 1813. The primary te ...
. In 1997, Quaggin returned to Toronto to study developmental biology with
Janet Rossant Janet Rossant, (born 13 July 1950) is a developmental biologist well known for her contributions to the understanding of the role of genes in embryo development. She is a world renowned leader in developmental biology. Her current research inte ...
at the Lunenfeld Institute of Mount Sinai Hospital. It was during her lab research with Rossant that she discovered a gene critical for the development of the kidneys, heart and lungs. By 2000, Quaggin and her research team were cloning mice lacking that vital gene in order to study their kidneys. The next year, she received the Joe Doupe Young Investigator Award.


Career

Quaggin accepted a faculty position at the University of Toronto, where she spent 13 years as a senior scientist at the Samuel Lunenfeld Research Institute, a nephrologist at St. Michael's Hospital, and the Gabor-Zellerman Professor in renal medicine. In 2006, she was named a Tier 2
Canada Research Chair Canada Research Chair (CRC) is a title given to certain Canadian university research professors by the Canada Research Chairs Program. Program goals The Canada Research Chair program was established in 2000 as a part of the Government of Canada ...
in Vascular Biology, which granted her $500,000 over 5 years. Two years later, Quaggin and Laura Barison discovered that VEGF inhibitors, an antibody used to treat many forms of cancer, was causing renal failure. She was also elected chair for the Abstract Selection Committees for Glomerular Disease with the
American Society of Nephrology Founded in 1966, the American Society of Nephrology (ASN) is the world's largest professional society devoted to the study of kidney disease. Composed of over 20,000 physicians and scientists, ASN promotes expert patient care, advances medical r ...
. The next year, Quaggin was the recipient of the 2009 KFOC Medal for Research Excellence by the
Kidney Foundation of Canada The Kidney Foundation of Canada promotes organ donor awareness, and fundraises for kidney/renal research at various hospitals across Canada Canada is a country in North America. Its ten provinces and three territories extend from the ...
. In 2011, Quaggin was appointed the Gabor-Zellerman Chair in Renal Research in the Department of Medicine at the University of Toronto and Deputy Editor and for
Journal of the American Society of Nephrology The ''Journal of the American Society of Nephrology'' is a peer-reviewed medical journal covering nephrology. It was established in 1966 and is published by the American Society of Nephrology. The editor-in-chief is Josephine P. Briggs. According ...
. Quaggin also co-published a study in the journal '' Cell'' regarding the effects of VEGF in the kidney, including how it will impact drug therapies and treatment. In 2012, Quaggin was encouraged to join the faculty at
Northwestern University Northwestern University is a private research university in Evanston, Illinois. Founded in 1851, Northwestern is the oldest chartered university in Illinois and is ranked among the most prestigious academic institutions in the world. Charte ...
by Eric G. Neilson. She was eventually appointed the Charles Horace Mayo Professor of Medicine at Northwestern University Feinberg School of Medicine, and as Director of the Feinberg Cardiovascular Research Institute and chief of the Division of Nephrology. At the Northwestern University Feinberg School of Medicine, Quaggin and Amani Fawzi discovered a cause of glaucoma in animals and began developing an eye drop aimed at curing the disease. Together with her PhD student Ben Thomson, Quaggin developed one of the first models of animals with the glaucoma disease. In May 2013, she was elected to the Association of American Physicians. She also received the Alfred Newton Richards Award for basic science research in the field by the International Society of Nephrology. Eventually, Q BioMed Inc. gained the rights to acquire Mannin Research Inc., which was developing the eyedrops. In 2015, she was appointed the American Society of Nephrology's Councilor until 2022, sat on their Public Policy Board, and their and Blood and Lymphatic Development of the Kidney Board. In 2019, she was elected to the National Academy of Medicine. In 2023, she became the first woman Chair of the Department of Medicine at the Northwestern University Feinberg School of Medicine.


References

{{DEFAULTSORT:Quaggin, Susan Living people Members of the National Academy of Medicine Academic staff of the University of Toronto University of Toronto alumni Yale School of Medicine alumni Northwestern University faculty Scientists from Toronto Canadian women academics Canadian nephrologists 20th-century Canadian scientists 20th-century Canadian women scientists 21st-century Canadian scientists 21st-century Canadian women scientists Year of birth missing (living people) Physician-scientists