Surfeit is a human
gene cluster
A gene family is a set of homologous genes within one organism. A gene cluster is a group of two or more genes found within an organism's DNA that encode similar polypeptides, or proteins, which collectively share a generalized function and are ...
that consists of a group of very tightly linked genes on
chromosome 9
Chromosome 9 is one of the 23 pairs of chromosomes in humans. Humans normally have two copies of this chromosome, as they normally do with all chromosomes. Chromosome 9 spans about 138 million base pairs of nucleic acids (the building blocks of D ...
that do not share sequence similarity. Genes in this cluster are numbered 1 through 6:
SURF1
Surfeit locus protein 1 (SURF1) is a protein that in humans is encoded by the ''SURF1'' gene. The protein encoded by ''SURF1'' is a component of the mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex (MITRAC ...
,
SURF2
SURF2 is a protein which in humans is encoded by the ''SURF2'' gene
In biology, the word gene (from , ; "... Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''ge ...
,
SURF3
60S ribosomal protein L7a is a protein that in humans is encoded by the ''RPL7A'' gene.
Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are co ...
,
SURF4,
SURF5
Mediator of RNA polymerase II transcription subunit 22 is an enzyme that in humans is encoded by the ''MED22'' gene.
Function
This gene is located in the surfeit gene cluster, a group of very tightly linked housekeeping genes that do not shar ...
, and
SURF6
Surfeit locus protein 6 is a protein that in humans is encoded by the ''SURF6'' gene
In biology, the word gene (from , ; "... Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ...
.
References
Genes on human chromosome 9
{{Gene-9-stub