organic chemistry Organic chemistry is a subdiscipline within chemistry involving the scientific study of the structure, properties, and reactions of organic compounds and organic materials, i.e., matter in its various forms that contain carbon atoms.Clayden, J.; ...

sulfamation is the installation of either of two related

functional group In organic chemistry, a functional group is a substituent or moiety in a molecule that causes the molecule's characteristic chemical reactions. The same functional group will undergo the same or similar chemical reactions regardless of the rest ...

s, sulfamic acid (R₂NSO₃H) and sulfamate (R₂NSO₃⁻). Typical methods entail reaction of primary amines with sources of sulfur trioxide such as

pyridine-sulfur trioxide Sulfur trioxide pyridine complex is the compound with the formula C5H5NSO3. It is a colourless solid that dissolves in polar organic solvents. It is the adduct formed from the Lewis base pyridine and the Lewis acid sulfur trioxide. The compound ...

:{{cite journal , doi=10.1021/jo01314a033, title=Sulfonylamine-Mediated Sulfamation of Amines. A Mild, High Yield Synthesis of Sulfamic Acid Salts, year=1980, last1=DuBois, first1=Grant E., last2=Stephenson, first2=Rebecca A., journal=The Journal of Organic Chemistry, volume=45, issue=26, pages=5371–5373 :RNH₂ + SO₃ → RNHSO₃H Sulfamation can also be effected by treating the amine with the sulfate ester of

catechol Catechol ( or ), also known as pyrocatechol or 1,2-dihydroxybenzene, is a toxic organic compound with the molecular formula . It is the ''ortho'' isomer of the three isomeric benzenediols. This colorless compound occurs naturally in trace amount ...

(C₆H₄O₂SO₂).

References

Sulfur oxoacids Sulfamates