Suloctidil was a sulfur-containing aminoalcohol that was brought to market in the early 1970s as a

vasodilator Vasodilation, also known as vasorelaxation, is the widening of blood vessels. It results from relaxation of smooth muscle cells within the vessel walls, in particular in the large veins, large arteries, and smaller arterioles. Blood vessel wal ...

by Continental Pharma, a Belgian company. Continental was bought by

Monsanto The Monsanto Company () was an American agrochemical and agricultural biotechnology corporation founded in 1901 and headquartered in Creve Coeur, Missouri. Monsanto's best-known product is Roundup, a glyphosate-based herbicide, developed ...

in 1984, primarily on the promise of sales of suloctidil, which was approved in Europe at the time, but not in the US. However, in 1985 Monsanto halted development and withdrew the drug worldwide following reports of

liver toxicity Hepatotoxicity (from ''hepatic toxicity'') implies chemical-driven liver damage. Drug-induced liver injury (DILI) is a cause of acute and chronic liver disease caused specifically by medications and the most common reason for a drug to be withdr ...

References

Alcohols Beta-Hydroxyamphetamines Hepatotoxins Isopropyl compounds Thioethers Withdrawn drugs {{cardiovascular-drug-stub Cerebral vasodilators