Suloctidil was a sulfur-containing aminoalcohol that was brought to market in the early 1970s as a

vasodilator Vasodilation is the widening of blood vessels. It results from relaxation of smooth muscle cells within the vessel walls, in particular in the large veins, large arteries, and smaller arterioles. The process is the opposite of vasoconstriction, ...

by Continental Pharma, a Belgian company. Continental was bought by Monsanto in 1984, primarily on the promise of sales of suloctidil, which was approved in Europe at the time, but not in the US. However, in 1985 Monsanto halted development and withdrew the drug worldwide following reports of

liver toxicity Hepatotoxicity (from ''hepatic toxicity'') implies chemical-driven liver damage. Drug-induced liver injury is a cause of acute and chronic liver disease caused specifically by medications and the most common reason for a drug to be withdrawn fro ...

References

Hepatotoxins Phenylethanolamines Substituted amphetamines Thioethers Withdrawn drugs Alcohols Isopropyl compounds {{cardiovascular-drug-stub