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Sucharit Bhakdi is a retired Thai-German
microbiologist A microbiologist (from Ancient Greek, Greek ) is a scientist who studies microscopic life forms and processes. This includes study of the growth, interactions and characteristics of Microorganism, microscopic organisms such as bacteria, algae, f ...
. In 2020 and 2021 Bhakdi became a prominent source of
misinformation Misinformation is incorrect or misleading information. It differs from disinformation, which is ''deliberately'' deceptive. Rumors are information not attributed to any particular source, and so are unreliable and often unverified, but can turn ou ...
about the
COVID-19 pandemic The COVID-19 pandemic, also known as the coronavirus pandemic, is an ongoing global pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The novel virus was first identif ...
, claiming that the pandemic was "fake" and that
COVID-19 vaccine A COVID19 vaccine is a vaccine intended to provide acquired immunity against severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2), the virus that causes coronavirus disease 2019 ( COVID19). Prior to the COVID19 pandemic, an e ...
s were going to decimate the world's population. He was a professor at the
University of Mainz The Johannes Gutenberg University Mainz (german: Johannes Gutenberg-Universität Mainz) is a public research university in Mainz, Rhineland Palatinate, Germany, named after the printer Johannes Gutenberg since 1946. With approximately 32,000 stu ...
, where from 1991 to 2012 he was head of the Institute of Medical Microbiology and Hygiene. The university has disassociated itself from Bhakdi's views on the Coronavirus pandemic. In 2021 Bhakdi's publisher broke off relations following the appearance of an online video in which Bhakdi made antisemitic comments.


Early life and education

Bhakdi ( th, สุจริต ภักดี ) was born Sucharit Punyaratabandhu, th, สุจริต บุณยรัตพันธุ์, 1 November 1946, in
Washington, D.C. ) , image_skyline = , image_caption = Clockwise from top left: the Washington Monument and Lincoln Memorial on the National Mall, United States Capitol, Logan Circle, Jefferson Memorial, White House, Adams Morgan, ...
; his parents are Thai diplomats. In an interview, Bhakdi stated that his mother studied at Johns Hopkins University in Baltimore. Bhakdi studied at the Universities of
Bonn The federal city of Bonn ( lat, Bonna) is a city on the banks of the Rhine in the German state of North Rhine-Westphalia, with a population of over 300,000. About south-southeast of Cologne, Bonn is in the southernmost part of the Rhine-Ruhr r ...
,
Gießen Giessen, spelled Gießen in German (), is a town in the German state (''Bundesland'') of Hesse, capital of both the district of Giessen and the administrative region of Giessen. The population is approximately 90,000, with roughly 37,000 univers ...
,
Mainz Mainz () is the capital and largest city of Rhineland-Palatinate, Germany. Mainz is on the left bank of the Rhine, opposite to the place that the Main (river), Main joins the Rhine. Downstream of the confluence, the Rhine flows to the north-we ...
and
Copenhagen Copenhagen ( or .; da, København ) is the capital and most populous city of Denmark, with a proper population of around 815.000 in the last quarter of 2022; and some 1.370,000 in the urban area; and the wider Copenhagen metropolitan ar ...
, and at the Max Planck Institute of Immunobiology in Freiburg. He studied medicine at the
University of Bonn The Rhenish Friedrich Wilhelm University of Bonn (german: Rheinische Friedrich-Wilhelms-Universität Bonn) is a public research university located in Bonn, North Rhine-Westphalia, Germany. It was founded in its present form as the ( en, Rhine U ...
from 1963 to 1970, during part of which (from 1966 to 1970) he was a scholarship holder of the German Academic Exchange Service. Bhakdi worked for a while as a private assistant to the internal medicine specialist . In February 1971 he received his doctorate in medicine. From 1972 to 1978, he studied at the Max Planck Institute for Immunobiology in Freiburg on scholarships from the Max Planck Society at the Max Planck Institute of Immunobiology in Freiburg and the Alexander von Humboldt Foundation. He worked at the
University of Copenhagen The University of Copenhagen ( da, Københavns Universitet, KU) is a prestigious public university, public research university in Copenhagen, Copenhagen, Denmark. Founded in 1479, the University of Copenhagen is the second-oldest university in ...
for a year before moving to the Institute of Medical Microbiology at the Justus Liebig University in
Gießen Giessen, spelled Gießen in German (), is a town in the German state (''Bundesland'') of Hesse, capital of both the district of Giessen and the administrative region of Giessen. The population is approximately 90,000, with roughly 37,000 univers ...
, where he worked from 1977 to 1990. In July 1979 he
habilitated Habilitation is the highest university degree, or the procedure by which it is achieved, in many European countries. The candidate fulfills a university's set criteria of excellence in research, teaching and further education, usually including a ...
.


Scientific and medical career

Bhakdi was appointed C2 professor at Gießen in 1982. He spent a further year in Copenhagen and became C3 professor of medical microbiology (at Gießen again) in 1987 before being appointed to the
University of Mainz The Johannes Gutenberg University Mainz (german: Johannes Gutenberg-Universität Mainz) is a public research university in Mainz, Rhineland Palatinate, Germany, named after the printer Johannes Gutenberg since 1946. With approximately 32,000 stu ...
in 1990. From 1991 he headed the Institute of Medical Microbiology and Hygiene as a C4 professor. Bhakdi retired on 1 April 2012. Since 2016 he has been a visiting scholar at the
University of Kiel Kiel University, officially the Christian-Albrecht University of Kiel, (german: Christian-Albrechts-Universität zu Kiel, abbreviated CAU, known informally as Christiana Albertina) is a university in the city of Kiel, Germany. It was founded in ...
. Prior to his retirement, Bhakdi produced scientific work in the fields of bacteriology and atherosclerosis, and published multiple scientific articles in these areas.


Research career


The immune system

From 1972, Bhakdi researched the functioning of the body's non-specific defenses at the Max Planck Institute for Immunobiology in Freiburg. He contributed to a better understanding of the mechanisms with which the large molecules of the
complement system The complement system, also known as complement cascade, is a part of the immune system that enhances (complements) the ability of antibodies and phagocytic cells to clear microbes and damaged cells from an organism, promote inflammation, and at ...
in the blood render exogenous substances harmless. In 1978 Bhakdi discovered a protein that attacks and damages cells by sinking into the
cell membrane The cell membrane (also known as the plasma membrane (PM) or cytoplasmic membrane, and historically referred to as the plasmalemma) is a biological membrane that separates and protects the interior of all cells from the outside environment ( ...
, resulting in the formation of a pore (see
membrane attack complex The membrane attack complex (MAC) or terminal complement complex (TCC) is a complex of proteins typically formed on the surface of pathogen cell membranes as a result of the activation of the host's complement system, and as such is an effector ...
). This was the enforcer molecule of the complement system, which is formed on the surface of foreign cells as a result of a chain reaction involving the
immune system The immune system is a network of biological processes that protects an organism from diseases. It detects and responds to a wide variety of pathogens, from viruses to parasitic worms, as well as cancer cells and objects such as wood splinte ...
. This was followed by the discovery that
bacteria Bacteria (; singular: bacterium) are ubiquitous, mostly free-living organisms often consisting of one biological cell. They constitute a large domain of prokaryotic microorganisms. Typically a few micrometres in length, bacteria were among ...
, in turn, can also produce pore-forming proteins. Today it is known that the vast majority of pathogenic bacteria produce pore formers that damage host cells. In 1984 the
Royal Society The Royal Society, formally The Royal Society of London for Improving Natural Knowledge, is a learned society and the United Kingdom's national academy of sciences. The society fulfils a number of roles: promoting science and its benefits, re ...
in London invited Bhakdi to present the concept of cell membrane damage by pore formers. From then on, Bhakdi concentrated on research on this topic.


Atherosclerosis

Investigation of the complement system led Bhakdi to the area of atherosclerosis. In 1989 he discovered through animal experiments that the complement component 5 is activated in the vessel walls where
low density lipoprotein Low-density lipoprotein (LDL) is one of the five major groups of lipoprotein that transport all fat molecules around the body in extracellular water. These groups, from least dense to most dense, are chylomicrons (aka ULDL by the overall density ...
(LDL) is deposited. According to current understanding, atherosclerosis is a polygenic disease caused by a complex interplay of several environmental and genetic factors, especially
cholesterol Cholesterol is any of a class of certain organic molecules called lipids. It is a sterol (or modified steroid), a type of lipid. Cholesterol is biosynthesized by all animal cells and is an essential structural component of animal cell mem ...
. This is transported in the blood via LDL and absorbed by the cells that need it via cellular receptors. However, it can accumulate in the blood vessel walls during transport and oxidize there or even beforehand. This attracts
monocyte Monocytes are a type of leukocyte or white blood cell. They are the largest type of leukocyte in blood and can differentiate into macrophages and conventional dendritic cells. As a part of the vertebrate innate immune system monocytes also inf ...
s, which take up the oxidized LDL and turn into "
foam cell Foam cells, also called lipid-laden macrophages, are a type of cell that contain cholesterol. These can form a plaque that can lead to atherosclerosis and trigger heart attacks and stroke. Foam cells are fat-laden cells with a M2 macrophage-like ...
s". These then trigger chronic inflammatory reactions that damage the vascular wall. In 1998, Bhakdi and his team of colleagues put forward the "Mainz hypothesis" that atherosclerosis is only caused monocausally by the lack of removal of LDL. According to Bhakdi's hypothesis, LDL is generally not oxidized, but cholesterol is also absorbed by monocytes and foam cells are formed. However, the
high density lipoprotein High-density lipoprotein (HDL) is one of the five major groups of lipoproteins. Lipoproteins are complex particles composed of multiple proteins which transport all fat molecules (lipids) around the body within the water outside cells. They are ty ...
(HDL) can remove cholesterol again. If, however, a certain amount of LDL accumulates locally on the vascular wall and cannot be removed, part of the immune system causes inflammatory reactions that lead to atherosclerosis. In this way, early-stage atherosclerosis could be reversed if the LDL blood level (and
blood pressure Blood pressure (BP) is the pressure of circulating blood against the walls of blood vessels. Most of this pressure results from the heart pumping blood through the circulatory system. When used without qualification, the term "blood pressure" r ...
) was lowered and the HDL level increased. Bhakdi's hypothesis, however, is not reflected in current opinion.


Memberships and functions

* Member of the Collaborative Research Centres of the German Research Foundation "Proteins as Tools in Biology" at the University of Giessen (1987-1990), * Deputy Spokesperson of the Collaborative Research Center "Immunopathogenesis" (1990-1999) * Spokesperson of the Collaborative Research Center "490 Infection and Persistence in Infections" in Mainz (2000-2011). * Co-founder and board member of the Association of Physicians and Scientists for Health, Freedom and Democracy, which was founded in May 2020 and lost its non-profit status in October 2020. The purpose of the association is to take action against the German government’s measures to contain the corona pandemic. In autumn 2020 he was one of the first signatories of the "appeal for free debating spaces" (, a German adaptation of the project "A Letter on Justice and Open Debate" by the American Thomas C. Williams, which was previously launched in the USA.). He was Editor in Chief of ''
Medical Microbiology and Immunology ''Medical Microbiology and Immunology'' is a peer-reviewed medical journal covering all aspects of the interrelationship between infectious agents and their hosts, with microbial and viral pathogenesis and the immunological host response to infe ...
'' from 1990 to 2012.


Prominence during COVID-19 pandemic

During the COVID-19 pandemic, Bhakdi started a
YouTube YouTube is a global online video platform, online video sharing and social media, social media platform headquartered in San Bruno, California. It was launched on February 14, 2005, by Steve Chen, Chad Hurley, and Jawed Karim. It is owned by ...
channel proposing that the number of deaths stemming from
SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) is a strain of coronavirus that causes COVID-19 (coronavirus disease 2019), the respiratory illness responsible for the ongoing COVID-19 pandemic. The virus previously had a ...
infection had been overstated. In November 2020 his account was terminated for violating YouTube's community guidelines. One of his first videos was published 18 March 2020; it
went viral Viral phenomena or viral sensation are objects or patterns that are able to replicate themselves or convert other objects into copies of themselves when these objects are exposed to them. Analogous to the way in which viruses propagate, the ter ...
, with 300,000 views by 23 March. In the video, he predicted the worst "horror scenario" would be a million infections and 30 deaths a day in Germany, and that death rates in Northern Italy and China were higher only because of high
air pollution Air pollution is the contamination of air due to the presence of substances in the atmosphere that are harmful to the health of humans and other living beings, or cause damage to the climate or to materials. There are many different types ...
there (even though Germany typically has more deaths due to pollution than Italy). Bhakdi has made a number of false statements about the
COVID-19 pandemic The COVID-19 pandemic, also known as the coronavirus pandemic, is an ongoing global pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The novel virus was first identif ...
, saying that the pandemic is a "fake", that face masks and
quarantine A quarantine is a restriction on the movement of people, animals and goods which is intended to prevent the spread of disease or pests. It is often used in connection to disease and illness, preventing the movement of those who may have been ...
s are "nonsense" and that the
COVID-19 vaccine A COVID19 vaccine is a vaccine intended to provide acquired immunity against severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2), the virus that causes coronavirus disease 2019 ( COVID19). Prior to the COVID19 pandemic, an e ...
s are deadly and will decimate the global population. He has been otherwise criticised for his theses on the COVID-19 pandemic; according to , they are considered unscientific by a majority of experts.


Bhakdi's criticisms of the COVID-19 pandemic response

His criticisms of states' (most particularly Germany's) reactions to the COVID-19 pandemic have included: *Writing an open Letter in March 2020 to German Chancellor Angela Merkel regarding the "socio-economic consequences of the drastic containment measures which are currently being applied in large parts of Europe" *Posting videos on YouTube claiming, for example, that the government was overreacting because the virus posed no more threat than
influenza Influenza, commonly known as "the flu", is an infectious disease caused by influenza viruses. Symptoms range from mild to severe and often include fever, runny nose, sore throat, muscle pain, headache, coughing, and fatigue. These symptoms ...
, and that any
COVID-19 vaccine A COVID19 vaccine is a vaccine intended to provide acquired immunity against severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2), the virus that causes coronavirus disease 2019 ( COVID19). Prior to the COVID19 pandemic, an e ...
would be "pointless". *Participation in May 2020 in the writing of a "position paper of the BMI" by an employee of the German crisis management department. The Federal Ministry distanced itself from the position, calling the paper a "private opinion" circulating on official letterhead, and released the chief government councilor Stephan Kohn from duty. *He is the co-author of ''Corona, False Alarm? Facts and Figures'' (2020), German: (Corona Fehlalarm''?') and ''Corona Unmasked. Neue Daten, Zahlen, Hintergründe''. (Goldegg, Berlin/Wien 2021, . An earlier book of his was published in 2016, ''Schreckgespenst Infektionen – Mythen, Wahn und Wirklichkeit'' (''tr. "Bogeyman Infections - Myths, Delusions and Reality"'') . He published these books together with his wife, , a biologist and biochemist at the Quincke Research Center,
Christian-Albrechts-Universität zu Kiel Kiel University, officially the Christian-Albrecht University of Kiel, (german: Christian-Albrechts-Universität zu Kiel, abbreviated CAU, known informally as Christiana Albertina) is a university in the city of Kiel, Germany. It was founded in ...
. *Describing Germany in December 2020 as a "health dictatorship", saying he wanted to emigrate to
Thailand Thailand ( ), historically known as Siam () and officially the Kingdom of Thailand, is a country in Southeast Asia, located at the centre of the Indochinese Peninsula, spanning , with a population of almost 70 million. The country is bo ...
because of this.


Responses to Bhakdi's claims

Bhakdi's claims, in particular in his YouTube videos and in the book ''Corona Fehlalarm?'', have been extensively fact-checked and found to be variously unsubstantiated, misleading, or false. In Germany, fact-checking activity has included articles at
ZDF ZDF (, short for Zweites Deutsches Fernsehen; ; "Second German Television") is a German public-service television broadcaster based in Mainz, Rhineland-Palatinate. It is run as an independent nonprofit institution, which was founded by all fe ...
, the Austrian independent fact-checkers
Mimikama Mimikama is a fact-checking site based in Austria Austria, , bar, Östareich officially the Republic of Austria, is a country in the southern part of Central Europe, lying in the Eastern Alps. It is a federation of nine states, one ...
, dpa,dpa Faktencheck
24 March 2020, accessed 2 May 2021.
SWR3swr3 Faktencheck
21. April 2020. accessed 2 May 2021.
and the German non-profit correctiv.org. In March 2020, ZDF said "His theses are unscientific, his numbers too low", Mimikama that his statements are "contrary to the scientific consensus of numerous experts, professors and colleagues and was described as largely dubious, unscientific and incorrect". Correctiv fact-checked one of Bhakdi's YouTube videos in June 2020, and found a number of problematic claims, including the claim that any
COVID-19 vaccine A COVID19 vaccine is a vaccine intended to provide acquired immunity against severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2), the virus that causes coronavirus disease 2019 ( COVID19). Prior to the COVID19 pandemic, an e ...
would be "pointless", and that the virus posed no more threat than
influenza Influenza, commonly known as "the flu", is an infectious disease caused by influenza viruses. Symptoms range from mild to severe and often include fever, runny nose, sore throat, muscle pain, headache, coughing, and fatigue. These symptoms ...
. On the basis of fact checks by Correctiv, ZDF,
die Welt ''Die Welt'' ("The World") is a German national daily newspaper, published as a broadsheet by Axel Springer SE. ''Die Welt'' is the flagship newspaper of the Axel Springer publishing group. Its leading competitors are the ''Frankfurter Allg ...
,
Der Spiegel ''Der Spiegel'' (, lit. ''"The Mirror"'') is a German weekly news magazine published in Hamburg. With a weekly circulation of 695,100 copies, it was the largest such publication in Europe in 2011. It was founded in 1947 by John Seymour Chaloner ...
and Bayerischer Rundfunk, the
Süddeutsche Zeitung The ''Süddeutsche Zeitung'' (; ), published in Munich, Bavaria, is one of the largest daily newspapers in Germany. The tone of SZ is mainly described as centre-left, liberal, social-liberal, progressive-liberal, and social-democrat. History ...
summed up in April 2020: "What Wodarg and Bhakdi say is not completely wrong, but they mix facts with speculation and disinformation."Corona-Falschmeldungen erreichen ein Millionenpublikum
(''tr. "Corona false reports reach an audience of millions"'') 10 April 2020, ''www.sueddeutsche.de'' accessed 2 May 2021.
Writing for ''
Foreign Policy A State (polity), state's foreign policy or external policy (as opposed to internal or domestic policy) is its objectives and activities in relation to its interactions with other states, unions, and other political entities, whether bilaterall ...
'', in September 2020 Tyson Barker (Head of
DGAP The German Council on Foreign Relations (german: Deutsche Gesellschaft für Auswärtige Politik e. V. (DGAP)) is Germany's national foreign policy network and policy research institute. As an independent, private, non-partisan and non-profit orga ...
's Technology & Global Affairs Program) described Bhakdi as a prominent example from a "crop of debunked but credentialed so-called experts minting conspiracy theories and undermining fact-based information". In October 2020 the University of Mainz issued a statement to the effect that it does not support Bhakdi's views. (''tr. "University distances itself from Corona critic Bhakdi"'') 2 November 2020 ''www.swr.de'' Accessed 4 December 2020


Political activism, antisemitism

In 2021, Bhakdi was a founder of the new German political party dieBasis, which emerged out of the " Querdenken" political movement, standing as a candidate in the
2021 German federal election Federal elections in Germany, Federal elections were held in Germany on 26 September 2021 to elect the members of the List of members of the 20th Bundestag, 20th Bundestag. States of Germany, State elections in 2021 Berlin state election, Berli ...
in
North Rhine-Westphalia North Rhine-Westphalia (german: Nordrhein-Westfalen, ; li, Noordrien-Wesfale ; nds, Noordrhien-Westfalen; ksh, Noodrhing-Wäßßfaale), commonly shortened to NRW (), is a States of Germany, state (''Land'') in Western Germany. With more tha ...
. In April 2021, the antisemitism commissioner for the state of
Baden-Württemberg Baden-Württemberg (; ), commonly shortened to BW or BaWü, is a German state () in Southwest Germany, east of the Rhine, which forms the southern part of Germany's western border with France. With more than 11.07 million inhabitants across a ...
identified the Querdenken movement as providing space for antisemitic conspiracy theories, noting that Bhakdi singled out the German-Jewish minister of education in
Schleswig-Holstein Schleswig-Holstein (; da, Slesvig-Holsten; nds, Sleswig-Holsteen; frr, Slaswik-Holstiinj) is the northernmost of the 16 states of Germany, comprising most of the historical duchy of Holstein and the southern part of the former Duchy of Sch ...
,
Karin Prien Karin Prien (born 26 June 1965) is a German lawyer and politician of the Christian Democratic Union (CDU) who has been serving as State Minister of Education, Science and Culture of Schleswig-Holstein in the government of Minister-President Da ...
, as "poisoning our children with CO2". In a video released as part of his campaign, Bhakdi articulated antisemitic views, saying Israel is "even worse" than Nazi Germany, adding that "that’s the bad thing about Jews: They learn well...There is no people that learns better than they do. But they have now learned the evil — and implemented it. That is why Israel is now...a living hell". The Austrian publisher of three of Bhakdi’s books on the pandemic, , said that it was severing ties with the author. Bhakdi was criticised by antisemitism commissioners for the states of Berlin and
Baden-Württemberg Baden-Württemberg (; ), commonly shortened to BW or BaWü, is a German state () in Southwest Germany, east of the Rhine, which forms the southern part of Germany's western border with France. With more than 11.07 million inhabitants across a ...
.


Awards


Professional awards

* 1979 Justus Liebig University Giessen PrizeInstitutsgeschichte Geschichte des Institutes für Medizinische Mikrobiologie in Gießen (bis zum Jahr 2000)
''tr. History of the Institute History of the Institute of Medical Microbiology in Gießen (until 2000)'' ''www.ukgm.de'', accessed 25 November 2020
* 1980 Konstanz Medicine Prize * 1987 * 1988 Dr. Friedrich Sasse Prize * 1989 Ludwig Schunk Prize for Medicine * 1989 Robert-Koch-Förderpreis of Clausthal-Zellerfeld * 1991
Gay-Lussac Humboldt Prize Joseph Louis Gay-Lussac (, , ; 6 December 1778 – 9 May 1850) was a French chemist and physicist. He is known mostly for his discovery that water is made of two parts hydrogen and one part oxygen (with Alexander von Humboldt), for two laws ...
* 2001
Aronson Prize The Aronson Prize (german: Aronson-Preis) is a prize awarded for achievements in microbiology and immunology. It was established by the will of the pediatrician and bacteriologist Hans Aronson and has been awarded since 1921. Aronson bequeathed ...
for „wegweisende Arbeiten auf dem Gebiet des Komplementsystems und bakterieller Toxine“ ''tr. "pioneering work in the field of the complement system and bacterial toxins"'' * 2005 H. W. Hauss Award * 2005 Verdienstorden des Landes Rheinland-Pfalz * 2009 Rudolf-Schönheimer Medal of the


Negative award

Following the publicity accorded to Bhakdi's statements and publications regarding Covid-19 during 2020, the
Gesellschaft zur wissenschaftlichen Untersuchung von Parawissenschaften The Gesellschaft zur wissenschaftlichen Untersuchung von Parawissenschaften (GWUP) (English: ''Society for the Scientific Investigation of Pseudosciences'') is a non-profit organisation promoting scientific skepticism, headquartered in Roßdorf, ...
(English: ''Society for the Scientific Investigation of Pseudosciences'') named him as winner of the 2020
Goldenes Brett The award Das Goldene Brett vorm Kopf (English translation: "''The Golden Blockhead''", literal translation "''The Golden Board in Front of the Head''") is a negative prize awarded by the Society for the Scientific Investigation of Pseudosciences ...
, awarded to Bhakdi as the "most astonishing pseudo-scientific nuisance" of the year.


References

{{DEFAULTSORT:Bhakdi, Sucharit 1946 births Living people German medical researchers Medical Microbiology and Immunology editors Thai emigrants to Germany Vaccine hesitancy