Subungual Exostosis
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Subungual exostoses are a type of non-cancerous
bone tumor A bone tumor is an abnormal growth of tissue in bone, traditionally classified as noncancerous (benign) or cancerous (malignant). Cancerous bone tumors usually originate from a cancer in another part of the body such as from lung, breast, thyroi ...
of the chondrogenic type, and consists of
bone A bone is a Stiffness, rigid Organ (biology), organ that constitutes part of the skeleton in most vertebrate animals. Bones protect the various other organs of the body, produce red blood cell, red and white blood cells, store minerals, provid ...
and
cartilage Cartilage is a resilient and smooth type of connective tissue. In tetrapods, it covers and protects the ends of long bones at the joints as articular cartilage, and is a structural component of many body parts including the rib cage, the neck an ...
. It usually projects from the upper surface of the
big toe Toes are the digits (fingers) of the foot of a tetrapod. Animal species such as cats that walk on their toes are described as being ''digitigrade''. Humans, and other animals that walk on the soles of their feet, are described as being ''plant ...
underlying the nailbed, giving rise to a painful swelling that destroys the nail. Subsequent ulceration and infection may occur. There is an association with trauma and infection. Diagnosis involves
medical imaging Medical imaging is the technique and process of imaging the interior of a body for clinical analysis and medical intervention, as well as visual representation of the function of some organs or tissues (physiology). Medical imaging seeks to rev ...
to exclude other similar conditions, particularly osteochondroma.
X-ray An X-ray, or, much less commonly, X-radiation, is a penetrating form of high-energy electromagnetic radiation. Most X-rays have a wavelength ranging from 10  picometers to 10  nanometers, corresponding to frequencies in the range 30&nb ...
appearance may reveal a bony protuberance attached to the top or side surface of a toe bone. Treatment is by surgical excision and is effective. More than half are under the age of 18 years and males are affected equally to females. Combined with bizarre parosteal osteochondromatous proliferation, they comprise <5% of cartilage tumors.


Signs and symptoms

They tend to be painful due to the pressure applied to the nail bed and plate. They can involve destruction of the nail bed. These lesions are not true osteochondromas, rather it is a reactive cartilage metaplasia. The reason it occurs on the dorsal aspect is because the periosteum is loose dorsally but very tightly adherent volarly.Murphey MD, Choi JJ, Kransdorf MJ, et al: Imaging of osteochondroma: variants and complications with radiologic-pathologic correlation. Radiographics 20:1407-1434, 2000


Diagnosis

Diagnosis involves
medical imaging Medical imaging is the technique and process of imaging the interior of a body for clinical analysis and medical intervention, as well as visual representation of the function of some organs or tissues (physiology). Medical imaging seeks to rev ...
. Differential diagnosis includes mainly bizarre parosteal osteochondromatous proliferation (BPOP), which is more irregular and tends to involve the middle of the finger or toe rather than the end near the nail. They are distinct from subungual osteochondroma.


Treatment

Treatment is by surgical excision and is effective. File:Subungual_exostosis_02.JPG, Subungual exostosis (2/3) File:Subungual_exostosis_03.JPG, Subungual exostosis (3/3), after excision


Epidemiology

It tends to occur in children and adolescents. Combined with BPOP, they account for less than 5% of cartilage tumors.


See also

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Sternal cleft Sternal clefts are rare congenital malformations that result from defective embryologic fusion of paired mesodermal bands in the ventral midline. They may be associated with other midline defects (as in pentalogy of Cantrell). It may also occur in ...
*
List of cutaneous conditions Many skin conditions affect the human integumentary system—the organ system covering the entire surface of the body and composed of skin, hair, nails, and related muscle and glands. The major function of this system is as a barrier against t ...


References


External links

Musculoskeletal disorders Dermal and subcutaneous growths {{musculoskeletal-disease-stub