''Amycolatopsis orientalis'' is a
Gram-positive
In bacteriology, gram-positive bacteria are bacteria that give a positive result in the Gram stain test, which is traditionally used to quickly classify bacteria into two broad categories according to their type of cell wall.
Gram-positive bac ...
bacterium
Bacteria (; singular: bacterium) are ubiquitous, mostly free-living organisms often consisting of one biological cell. They constitute a large domain of prokaryotic microorganisms. Typically a few micrometres in length, bacteria were a ...
in the phylum
Actinomycetota
The ''Actinomycetota'' (or ''Actinobacteria'') are a phylum of all gram-positive bacteria. They can be terrestrial or aquatic. They are of great economic importance to humans because agriculture and forests depend on their contributions to soi ...
.
It produces several substances with antimicrobial properties, including the antibiotic drug
vancomycin
Vancomycin is a glycopeptide antibiotic medication used to treat a number of bacterial infections. It is recommended intravenously as a treatment for complicated skin infections, bloodstream infections, endocarditis, bone and joint infection ...
.
History
''A. orientalis'' was originally discovered by
Edmund Kornfeld
Edmund Carl Kornfeld (24 February 1919 – 22 June 2012) was an American organic chemist who devoted his life to the research of new drugs. His leading discovery, with the help of a team, was an antibiotic that was later named vancomycin.Griffith ...
, an organic chemist at
Eli Lilly and Company
Eli Lilly and Company is an American pharmaceutical company headquartered in Indianapolis, Indiana, with offices in 18 countries. Its products are sold in approximately 125 countries. The company was founded in 1876 by, and named after, Colon ...
, in a soil sample gathered by a missionary from forests on the island of
Borneo
Borneo (; id, Kalimantan) is the List of islands by area, third-largest island in the world and the largest in Asia. At the geographic centre of Maritime Southeast Asia, in relation to major Indonesian islands, it is located north of Java Isl ...
. The antibiotic vancomycin was first isolated from the bacteria in 1953.
References
Pseudonocardiales
Bacteria described in 1956
{{Streptomyces-stub