''Saccharopolyspora erythraea'' is a species of actinomycete bacteria within the genus ''
Saccharopolyspora
''Saccharopolyspora'' is a genus of bacteria within the family Pseudonocardiaceae
The Pseudonocardiaceae are a family of bacteria in the order Actinomycetales and the only member of the suborder Pseudonocardineae.
Genomics
The species within ...
''.
''Saccharopolyspora erythraea'' produces the
macrolide antibiotic
erythromycin
Erythromycin is an antibiotic used for the treatment of a number of bacterial infections. This includes respiratory tract infections, skin infections, chlamydia infections, pelvic inflammatory disease, and syphilis. It may also be used duri ...
.
Cytochrome P450
Cytochromes P450 (CYPs) are a Protein superfamily, superfamily of enzymes containing heme as a cofactor (biochemistry), cofactor that functions as monooxygenases. In mammals, these proteins oxidize steroids, fatty acids, and xenobiotics, and are ...
eryF (CYP107A1) originally from the bacterium is responsible for the biosynthesis of the antibiotic by C6-hydroxylation of the macrolide
6-deoxyerythronolide B.
Small non-coding RNAs have been suggested to be involved in regulation of the secondary metabolite biosynthesis.
References
External links
Type strain of ''Saccharopolyspora erythraea'' at Bac''Dive'' - the Bacterial Diversity Metadatabase
Pseudonocardineae
{{Pseudonocardineae-stub