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The Strategic National Stockpile (SNS), originally called the National Pharmaceutical Stockpile (NPS), is the United States' national repository of
antibiotic An antibiotic is a type of antimicrobial substance active against bacteria. It is the most important type of antibacterial agent for fighting bacterial infections, and antibiotic medications are widely used in the treatment and prevention of ...
s,
vaccine A vaccine is a biological Dosage form, preparation that provides active acquired immunity to a particular infectious disease, infectious or cancer, malignant disease. The safety and effectiveness of vaccines has been widely studied and verifie ...
s, chemical
antidote An antidote is a substance that can counteract a form of poisoning. The term ultimately derives from the Greek term φάρμακον ἀντίδοτον ''(pharmakon) antidoton'', "(medicine) given as a remedy". Antidotes for anticoagulants are s ...
s,
antitoxin An antitoxin is an antibody with the ability to neutralize a specific toxin. Antitoxins are produced by certain animals, plants, and bacterium, bacteria in response to toxin exposure. Although they are most effective in neutralizing toxins, the ...
s, and other critical
medical supplies A medical device is any device intended to be used for medical purposes. Significant potential for hazards are inherent when using a device for medical purposes and thus medical devices must be proved safe and effective with reasonable assur ...
. Its website states:
"The Strategic National Stockpile's role is to supplement state and local supplies during public health emergencies. Many states have products stockpiled, as well. The supplies, medicines, and devices for life-saving care contained in the stockpile can be used as a short-term stopgap buffer when the immediate supply of adequate amounts of these materials may not be immediately available."
In at least 10 government reports published from 2003 to 2015, federal officials predicted that the U.S. would experience a shortage of ventilators and other medical supplies were a large-scale infectious disease outbreak to occur.


Locations

The actual supply of drugs and supplies that make up the SNS are located in 12 secret locations strategically placed throughout the US. The locations appear to look like ordinary commercial warehouses. Inside the warehouses, supplies are stacked on shelves that can measure five stories high. Armed personnel guard the warehouse contents and, according to
NPR National Public Radio (NPR, stylized in all lowercase) is an American privately and state funded nonprofit media organization headquartered in Washington, D.C., with its NPR West headquarters in Culver City, California. It differs from other ...
in 2020, during the
COVID-19 Coronavirus disease 2019 (COVID-19) is a contagious disease caused by a virus, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The first known case was COVID-19 pandemic in Hubei, identified in Wuhan, China, in December ...
global pandemic, "rows of ventilators, which can support people who are having trouble breathing, are kept charged up and ready to roll at a moment's notice."


Composition

The SNS holds a variety of items that would be helpful to the general population in the event of a widespread disease outbreak.


12-hour push pack

Each push pack weighs about . Its contents include broad-spectrum oral and intravenous antibiotics, emergency medicines, IV fluids and kits, airway equipment, bandages, vaccines, antitoxins, and ventilators. The material deploys by unmarked trucks and airplanes within 12 hours of the receipt of a request by the CDC. The U.S. Marshals Service provides armed security from these federal sites to local destinations. The SNS has adequate vaccines and countermeasures in its stockpile, including 300 million smallpox treatment courses and enough
anthrax vaccines Anthrax vaccines are vaccines to prevent the livestock and human disease anthrax, caused by the bacterium ''Bacillus anthracis''. They have had a prominent place in the history of medicine, from Pasteur's pioneering 19th-century work with cattle ...
to handle a three-city incident.


CHEMPACK

CHEMPACKs contain nerve agent antidotes to help in the event of a
nerve agent Nerve agents, sometimes also called nerve gases, are a class of organic chemicals that disrupt the mechanisms by which nerves transfer messages to organs. The disruption is caused by the blocking of acetylcholinesterase (AChE), an enzyme that ...
attack or industrial accident. As of 2015, 1,960 CHEMPACKs were forward-deployed in more than 1,340 locations across each state and territory of the United States.


History


Cold War Era

During the first decade of the
Cold War The Cold War is a term commonly used to refer to a period of geopolitical tension between the United States and the Soviet Union and their respective allies, the Western Bloc and the Eastern Bloc. The term '' cold war'' is used because the ...
, the United States accumulated a civil defense medical stockpile at 32 storage facilities. The supplies began to degrade in the 1960s, and were disposed of and the stockpile program closed in 1974.


Clinton Administration

In April 1998, President
Bill Clinton William Jefferson Clinton ( né Blythe III; born August 19, 1946) is an American politician who served as the 42nd president of the United States from 1993 to 2001. He previously served as governor of Arkansas from 1979 to 1981 and agai ...
read the
Richard Preston Richard Preston (born August 5, 1954) is a writer for ''The New Yorker'' and bestselling author who has written books about infectious disease, bioterrorism, redwoods and other subjects, as well as fiction. Biography Preston was born in Cambri ...
novel '' The Cobra Event'', a fiction book about a mad scientist spreading a virus throughout New York City. As a result, Clinton held a meeting with scientists and cabinet officials to discuss the threat of bioterrorism. He was so impressed that he asked the experts to meet with senior-level aides at the Department of Defense and in the Department of Health and Human Services. At that time, the government had stockpiles of medications for military personnel, but did not have them for civilians. Shortly after, ''
The Washington Post ''The Washington Post'' (also known as the ''Post'' and, informally, ''WaPo'') is an American daily newspaper published in Washington, D.C. It is the most widely circulated newspaper within the Washington metropolitan area and has a large nati ...
'' wrote that Clinton surprised many in Washington at how fast he and his
National Security Council A national security council (NSC) is usually an executive branch governmental body responsible for coordinating policy on national security issues and advising chief executives on matters related to national security. An NSC is often headed by a na ...
had moved to change that. By October, Clinton signed into law a new budget of $51 million for pharmaceutical and vaccine stockpiling to be carried out by the CDC. The US Congress appropriated funds for the CDC to create a pharmaceutical and vaccine stockpile to handle biological and chemical threats from disease that could affect large numbers of the US civilian population, in Public Law 105–277 dated October 21, 1998. The original name was the National Pharmaceutical Stockpile (NPS) program, but additional materials have been added to the stockpile since the original authorization .


Bush Administration

The federal government implemented a pandemic blueprint for distribution of Personal Protective Equipment (P.P.E.) from the Strategic National Stockpile, in coordination with public and private efforts. On March 1, 2003, the NPS was renamed the Strategic National Stockpile (SNS) program with joint management by
Department of Homeland Security The United States Department of Homeland Security (DHS) is the U.S. federal executive department responsible for public security, roughly comparable to the interior or home ministries of other countries. Its stated missions involve anti-terr ...
and
Department of Health and Human Services The United States Department of Health and Human Services (HHS) is a cabinet-level executive branch department of the U.S. federal government created to protect the health of all Americans and providing essential human services. Its motto is " ...
. In 2005 and in preparation for a predictable pandemic influenza, the Bush administration called for the coordination of domestic production and stockpiling of protective personal equipment. In 2006, the US Congress funded the integration of protective equipment to a Strategic National Stockpile: 52 million
surgical mask A surgical mask, also known by other names such as a medical face mask or procedure mask, is a personal protective equipment used by healthcare professionals that serves as a mechanical barrier that interferes with direct airflow in and out of re ...
s and 104 million N95 air-filtration masks were acquired and added. Public Health Emergency lists large-scale deployments from the SNS in response to emergencies. The SNS successfully deployed 12-hour "push packages" to
New York City New York, often called New York City or NYC, is the List of United States cities by population, most populous city in the United States. With a 2020 population of 8,804,190 distributed over , New York City is also the L ...
and
Washington, D.C. ) , image_skyline = , image_caption = Clockwise from top left: the Washington Monument and Lincoln Memorial on the National Mall, United States Capitol, Logan Circle, Jefferson Memorial, White House, Adams Morgan, ...
, in response to the
terrorist attacks on September 11, 2001 The September 11 attacks, commonly known as 9/11, were four coordinated suicide terrorist attacks carried out by al-Qaeda against the United States on Tuesday, September 11, 2001. That morning, nineteen terrorists hijacked four commer ...
, and managed inventory (MI) to numerous locations in response to the anthrax terrorist attacks of 2001. Following the landfall of Hurricanes
Katrina Katrina or Katrine may refer to: People * Katrina (given name) * Katrine (given name) Meteorology * List of storms named Katrina, a list of tropical cyclones designated as Katrina ** Hurricane Katrina, an exceptionally powerful Atlantic hurrican ...
and
Rita Rita may refer to: People * Rita (given name) * Rita (Indian singer) (born 1984) * Rita (Israeli singer) (born 1962) * Rita (Japanese singer) * Eliza Humphreys (1850–1938), wrote under the pseudonym Rita Places * Djarrit, also known as Rita, ...
on the Gulf coast of
Mississippi Mississippi () is a state in the Southeastern region of the United States, bordered to the north by Tennessee; to the east by Alabama; to the south by the Gulf of Mexico; to the southwest by Louisiana; and to the northwest by Arkansas. Miss ...
and
Louisiana Louisiana , group=pronunciation (French: ''La Louisiane'') is a state in the Deep South and South Central regions of the United States. It is the 20th-smallest by area and the 25th most populous of the 50 U.S. states. Louisiana is borde ...
in September 2005, the CDC deployed SNS assets, technical assistance and response units, plus the newly developed and rapidly deployable "federal medical contingency stations" to state-approved locations near or in the disaster areas. The contingency stations, later renamed Federal Medical Stations (FMS), are caches of equipment and supplies provided by the SNS, set up in local "buildings of opportunity" and staffed by local or federal medical personnel to provide
triage In medicine, triage () is a practice invoked when acute care cannot be provided for lack of resources. The process rations care towards those who are most in need of immediate care, and who benefit most from it. More generally it refers to prio ...
, low acuity care, and temporary holding of displaced patients for whom local acute care systems are damaged or destroyed.


Obama Administration

Since the original deployment following Hurricane Katrina, FMSs have been deployed to support other major disaster responses including
Superstorm Sandy Hurricane Sandy (unofficially referred to as ''Superstorm Sandy'') was an extremely destructive and strong Atlantic hurricane, as well as the largest Atlantic hurricane on record as measured by diameter, with tropical-storm-force winds spann ...
. The FMS program is a collaboration between CDC and the Office of Emergency Management under the HHS Assistant Secretary for Preparedness and Response. In 2014, responding to stakeholder feedback, a 50-bed FMS cache was developed and made available in addition to the original 250-bed FMS. The SNS released one-quarter of its antiviral drug inventory (
Tamiflu Oseltamivir, sold under the brand name Tamiflu, is an antiviral medication used to treat and prevent influenza A and influenza B, viruses that cause the flu. Many medical organizations recommend it in people who have complications or are at hig ...
and
Relenza Zanamivir is a medication used to treat and prevent influenza caused by influenza A and influenza B viruses. It is a neuraminidase inhibitor and was developed by the Australian biotech firm Biota Holdings. It was licensed to Glaxo in 1990 and ...
), personal protective equipment ( PPE), and respiratory protection devices, to help every US state respond to the
H1N1 In virology, influenza A virus subtype H1N1 (A/H1N1) is a subtype of influenza A virus. Major outbreaks of H1N1 strains in humans include the Spanish flu, the 1977 Russian flu pandemic and the 2009 swine flu pandemic. It is an orthomyxovirus ...
Influenza 2009 swine influenza outbreak in the United States. After the
2009 flu pandemic The 2009 swine flu pandemic, caused by the H1N1 influenza virus and declared by the World Health Organization (WHO) from June 2009 to August 2010, is the third recent flu pandemic involving the H1N1 virus (the first being the 1918–1920 Span ...
in which tens of millions of masks were distributed, fiscal constraints imposed by the agency's $600 million annual budget led officials to decide that replenishing a large inventory of N95 face masks was of less priority than stockpiling other equipment and drugs for diseases and disasters.


Trump Administration

During the
Trump administration Donald Trump's tenure as the List of presidents of the United States, 45th president of the United States began with Inauguration of Donald Trump, his inauguration on January 20, 2017, and ended on January 20, 2021. Trump, a Republican Party ...
, Trump falsely claimed his administration inherited an ‘empty’ stockpile from the previous administration. From 2017 to 2019, the Trump administration failed to replace masks and other supplies used in earlier disasters. In May 2020, in a House subcommittee meeting, whistle-blower Dr. Rick Bright, previous director of Department of Health and Human Services’ Biomedical Advanced Research and Development Authority, explained that the Trump administration had ignored his early warnings to stock up on masks and other supplies to combat the coronavirus. The
Office of the Assistant Secretary for Preparedness and Response The Administration for Strategic Preparedness and Response (ASPR) is an operating agency of the United States Public Health Service, U.S. Public Health Service within the United States Department of Health and Human Services, Department of Health ...
(ASPR) of the
Department of Health and Human Services The United States Department of Health and Human Services (HHS) is a cabinet-level executive branch department of the U.S. federal government created to protect the health of all Americans and providing essential human services. Its motto is " ...
has managed the Strategic National Stockpile since October 1, 2018. Prior to that, the stockpile was managed by the
Centers for Disease Control and Prevention The Centers for Disease Control and Prevention (CDC) is the national public health agency of the United States. It is a United States federal agency, under the Department of Health and Human Services, and is headquartered in Atlanta, Georgi ...
(CDC).


2020 COVID-19 pandemic

At the beginning of the
Covid-19 pandemic The COVID-19 pandemic, also known as the coronavirus pandemic, is an ongoing global pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The novel virus was first identif ...
, SNS was involved in providing supplies to the repatriation efforts of
State Department The United States Department of State (DOS), or State Department, is an United States federal executive departments, executive department of the Federal government of the United States, U.S. federal government responsible for the country's fore ...
employees from
China China, officially the People's Republic of China (PRC), is a country in East Asia. It is the world's most populous country, with a population exceeding 1.4 billion, slightly ahead of India. China spans the equivalent of five time zones and ...
and
Japan Japan ( ja, 日本, or , and formally , ''Nihonkoku'') is an island country in East Asia. It is situated in the northwest Pacific Ocean, and is bordered on the west by the Sea of Japan, while extending from the Sea of Okhotsk in the north ...
. It also shipped thousands of N95 masks to the states of
Washington Washington commonly refers to: * Washington (state), United States * Washington, D.C., the capital of the United States ** A metonym for the federal government of the United States ** Washington metropolitan area, the metropolitan area centered o ...
,
Massachusetts Massachusetts (Massachusett language, Massachusett: ''Muhsachuweesut assachusett writing systems, məhswatʃəwiːsət'' English: , ), officially the Commonwealth of Massachusetts, is the most populous U.S. state, state in the New England ...
, and
New York New York most commonly refers to: * New York City, the most populous city in the United States, located in the state of New York * New York (state), a state in the northeastern United States New York may also refer to: Film and television * '' ...
to respond to their surging infection rates. In March of 2020, SNS director Steven Adams said it had stockpiled 13 million masks and had placed an order for 500 million more by September of 2021. The SNS was criticized for containing over 5 million expired masks. On March 29, 2020, HHS accepted a donation of 30 million doses of hydroxychloroquine sulfate from
Sandoz Novartis AG is a Swiss-American multinational pharmaceutical corporation based in Basel, Switzerland and Cambridge, Massachusetts, United States (global research).name="novartis.com">https://www.novartis.com/research-development/research-loc ...
and one million doses of Resochin ( chloroquine phosphate) from
Bayer Bayer AG (, commonly pronounced ; ) is a German multinational corporation, multinational pharmaceutical and biotechnology company and one of the largest pharmaceutical companies in the world. Headquartered in Leverkusen, Bayer's areas of busi ...
Pharmaceuticals for use in treating hospitalized COVID-19 patients or in clinical trials. The SNS will work with the Federal Emergency Management Agency (FEMA) to deliver the doses to states. The
U.S. Food and Drug Administration The United States Food and Drug Administration (FDA or US FDA) is a federal agency of the Department of Health and Human Services. The FDA is responsible for protecting and promoting public health through the control and supervision of food ...
later withdrew Emergency Use Authorization for these drugs after studies found they had no benefit for treating COVID-19. On April 1, 2020,
Department of Homeland Security The United States Department of Homeland Security (DHS) is the U.S. federal executive department responsible for public security, roughly comparable to the interior or home ministries of other countries. Its stated missions involve anti-terr ...
officials told reporters that the cache of personal protective equipment stored by the SNS was almost depleted due to the
COVID-19 pandemic in the United States The COVID-19 pandemic in the United States is a part of the COVID-19 pandemic, worldwide pandemic of COVID-19, coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In the Uni ...
. This was later confirmed by President
Donald Trump Donald John Trump (born June 14, 1946) is an American politician, media personality, and businessman who served as the 45th president of the United States from 2017 to 2021. Trump graduated from the Wharton School of the University of Pe ...
. PPE from the SNS was sent directly to health facilities across the country. During the
COVID-19 pandemic The COVID-19 pandemic, also known as the coronavirus pandemic, is an ongoing global pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The novel virus was first identif ...
, states criticized the lack of availability of medical supplies from the federal stockpile. At a
White House The White House is the official residence and workplace of the president of the United States. It is located at 1600 Pennsylvania Avenue NW in Washington, D.C., and has been the residence of every U.S. president since John Adams in 1800. ...
press conference on April 2, 2020,
senior advisor In some countries, a senior advisor (also spelt senior adviser, especially in the UK) is an appointed position by the Head of State to advise on the highest levels of national and government policy. Sometimes a junior position to this is called a N ...
Jared Kushner Jared Corey Kushner (born January 10, 1981) is an American businessman and investor. He served as a senior advisor to 45th U.S. president Donald Trump, his father-in-law. Since leaving the White House, Kushner founded Affinity Partners, a pri ...
commented "The notion of the federal stockpile was it's supposed to be our stockpile. It's not supposed to be states' stockpiles that they then use." The idea that the stockpile was not a backup for states that run out of supplies was disputed by Governor
Laura Kelly Laura Jeanne Kelly (born January 24, 1950)"Laura Kelly,"
''Kansapedia,''
of Kansas, among others. The description of the stockpile, as listed on its website, was changed the day after Kushner's remarks to better align with them, from:
"Strategic National Stockpile is the nation’s largest supply of life-saving pharmaceuticals and medical supplies for use in a public health emergency severe enough to cause local supplies to run out. When state, local, tribal, and territorial responders request federal assistance to support their response efforts, the stockpile ensures that the right medicines and supplies get to those who need them most during an emergency. Organized for scalable response to a variety of public health threats, this repository contains enough supplies to respond to multiple large-scale emergencies simultaneously."
to:
"The Strategic National Stockpile's role is to supplement state and local supplies during public health emergencies. Many states have products stockpiled, as well. The supplies, medicines, and devices for life-saving care contained in the stockpile can be used as a short-term stopgap buffer when the immediate supply of adequate amounts of these materials may not be immediately available."
Washington State Washington (), officially the State of Washington, is a state in the Pacific Northwest region of the Western United States. Named for George Washington—the first U.S. president—the state was formed from the western part of the Washington ...
announced on April 5, 2020, that it would return more than 400 ventilators it had received from the Stockpile "... to help states facing higher numbers of COVID-19 cases." On April 8, 2020, HHS contracted with
DuPont DuPont de Nemours, Inc., commonly shortened to DuPont, is an American multinational chemical company first formed in 1802 by French-American chemist and industrialist Éleuthère Irénée du Pont de Nemours. The company played a major role in ...
for 2.25 million
Tyvek Tyvek () is a brand of synthetic flashspun high-density polyethylene fibers. The name "Tyvek" is a registered trademark of the American multinational chemical company DuPont, which discovered and commercialized Tyvek in the late 1950s and early ...
suits to be delivered to the SNS to be used as PPE for frontline healthcare workers. By April 13, 2020, HHS used the Defense Production Act (DPA) to contract for ventilator production with
General Electric General Electric Company (GE) is an American multinational conglomerate founded in 1892, and incorporated in New York state and headquartered in Boston. The company operated in sectors including healthcare, aviation, power, renewable energ ...
,
Hill-Rom Hill-Rom Holdings, Inc., doing business as Hillrom, is an American medical technology provider that is a subsidiary of Baxter International. History Hillrom is a wholly owned subsidiary of Baxter and was formally part of Hill-Rom Holdings, I ...
,
Medtronic Medtronic plc is an American medical device company. The company's operational and executive headquarters are in Minneapolis, Minnesota, and its legal headquarters are in Ireland due to its acquisition of Irish-based Covidien in 2015. While it ...
,
ResMed ResMed Inc. is a San Diego, California-based medical equipment company. It primarily provides cloud-connectable medical devices for the treatment of sleep apnea (such as CPAP devices and masks), chronic obstructive pulmonary disease (COPD), and o ...
, and Vyaire. Additionally, they contracted with Hamilton and Zoll for ventilator production without using the DPA. The seven contracts were expected to produce 137,431 ventilators by the end of 2020 at a total cost of $1.435 billion.


Biden administration

In January 2022, amidst a surge in cases caused by the more contagious
Omicron variant Omicron (B.1.1.529) is a variant of SARS-CoV-2 first reported to the World Health Organization (WHO) by the Network for Genomics Surveillance in South Africa on 24 November 2021. It was first detected in Botswana and has spread to become the ...
, the CDC updated its guidance to emphasize the greater protection from wearing
N95 mask An N95 filtering facepiece respirator, commonly abbreviated N95 respirator, is a particulate-filtering facepiece respirator that meets the U.S. National Institute for Occupational Safety and Health (NIOSH) N95 classification of air filtratio ...
s in indoor public spaces. The Biden Administration announced it would distribute 400 million N95 masks from the SNS which started arriving in late January and early February.


2022 monkeypox outbreak

The stockpile was again used during the 2022 monkeypox outbreak. In May 2022, the Centers for Disease Control (CDC) confirmed the United States released some of their Jynneos monkeypox vaccine supply from their Strategic National Stockpile for people who are "high-risk". On May 27, 2022, the CDC specified the indications for the Jynneos vaccine: research laboratory personnel, clinical laboratory personnel performing diagnostic testing for orthopoxviruses, designated response team members, and health care personnel who administer live smallpox Vaccine or care for patients infected with orthopoxviruses.


Criticism

In March of 2021, the ''
New York Times ''The New York Times'' (''the Times'', ''NYT'', or the Gray Lady) is a daily newspaper based in New York City with a worldwide readership reported in 2020 to comprise a declining 840,000 paid print subscribers, and a growing 6 million paid d ...
'' alleged mismanagement involving the Strategic National Stockpile, stating, "In one telling example, The Times found, the government approved a plan in 2015 to buy tens of millions of N95 respirators — lifesaving equipment for medical workers that has been in short supply because of Covid-19 — but the masks repeatedly lost out in the competition for funding over the years leading up to the pandemic, according to five former federal health officials involved in the effort. During the same period, Emergent sold the government nearly $1 billion in anthrax vaccines, financial disclosures show."


Related legislation

Section 403 of the Pandemic and All-Hazards Preparedness Reauthorization Act of 2013 (H.R. 307; 113th Congress) reauthorized the Strategic National Stockpile for FY2014-FY2018. It required the Secretary of Health and Human Services to: # submit to the appropriate congressional committees, to the extent that the disclosure of such information does not compromise national security, the annual review of the contents of the Stockpile; and # review and revise the contents of the Stockpile to ensure that the potential depletion of countermeasures currently in the Stockpile is identified and appropriately addressed, including through necessary replenishment.


See also

*


References


External links


Official site
* {{U.S. biological defense Biological warfare Centers for Disease Control and Prevention Strategic reserves of the United States Trump administration controversies