SraG (small RNA G) is a small
non-coding RNA (ncRNA). It is the functional product of a
gene
In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a ba ...
which is not translated into
protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, respo ...
.
This ncRNA was discovered in the bacteria ''
Escherichia coli
''Escherichia coli'' (),Wells, J. C. (2000) Longman Pronunciation Dictionary. Harlow ngland Pearson Education Ltd. also known as ''E. coli'' (), is a Gram-negative, facultative anaerobic, rod-shaped, coliform bacterium of the genus ''Escher ...
'' during a large scale computational screen for transcription signals and genomic features of known small RNA-encoding genes.
During this screen 14 novel ncRNA genes were identified, including
GlmZ,
SraB,
SraC and
SraD.
The expression of SraG was experimentally confirmed by
Northern blotting
The northern blot, or RNA blot,Gilbert, S. F. (2000) Developmental Biology, 6th Ed. Sunderland MA, Sinauer Associates. is a technique used in molecular biology research to study gene expression by detection of RNA (or isolated mRNA) in a sample.K ...
which also indicated this RNA undergoes specific cleavage processing.
The function of this RNA is unknown.
References
External links
*
Non-coding RNA
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