Spruce Pine may refer to:
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Pinus glabra
''Pinus glabra'', the spruce pine, is a tree found on the coastal plains of the southern United States, from southern South Carolina south to northern Florida and west to southern Louisiana. This pine is a straight-growing, medium-sized specie ...
'', a tree found on the coastal plains of the southern United States, commonly known as the Spruce pine
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Spruce Pine, Alabama, a census-designated place in Franklin County, Alabama, United States
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Spruce Pine, North Carolina, a town in Mitchell County, North Carolina, United States
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