A splicing factor is a protein involved in the removal of

introns An intron is any nucleotide sequence within a gene that is not expressed or operative in the final RNA product. The word ''intron'' is derived from the term ''intragenic region'', i.e. a region inside a gene."The notion of the cistron .e., gene ...

from strings of messenger RNA, so that the

exons An exon is any part of a gene that will form a part of the final mature RNA produced by that gene after introns have been removed by RNA splicing. The term ''exon'' refers to both the DNA sequence within a gene and to the corresponding sequenc ...

can bind together; the process takes place in particles known as spliceosomes. Genes are progressively switched off as we age, and splicing factors can reverse this trend. In a research paper, splicing factors were found to be produced upon application of

resveratrol Resveratrol (3,5,4′-trihydroxy-''trans''-stilbene) is a stilbenoid, a type of natural phenol, and a phytoalexin produced by several plants in response to injury or when the plant is under attack by pathogens, such as bacteria or fungi. Sources ...

analogues, which induced senescent cells to rejuvenate.

Notes

Biochemistry Spliceosome Ageing {{protein-stub