The Somatotropin family is a

protein family A protein family is a group of evolutionarily related proteins. In many cases, a protein family has a corresponding gene family, in which each gene encodes a corresponding protein with a 1:1 relationship. The term "protein family" should not be c ...

whose titular representative is

somatotropin Growth hormone (GH) or somatotropin, also known as human growth hormone (hGH or HGH) in its human form, is a peptide hormone that stimulates growth, cell reproduction, and cell regeneration in humans and other animals. It is thus important in h ...

, also known as

growth hormone Growth hormone (GH) or somatotropin, also known as human growth hormone (hGH or HGH) in its human form, is a peptide hormone that stimulates growth, cell reproduction, and cell regeneration in humans and other animals. It is thus important in h ...

, a hormone that plays an important role in growth control. Other members include choriomammotropin (lactogen), its placental analogue;

prolactin Prolactin (PRL), also known as lactotropin, is a protein best known for its role in enabling mammals to produce milk. It is influential in over 300 separate processes in various vertebrates, including humans. Prolactin is secreted from the pit ...

, which promotes lactation in the mammary gland, and placental prolactin-related proteins; proliferin and proliferin related protein; and somatolactin from various fishes.Benedet Perea, Susana (2008)
Growth hormone and somatolactin function during sexual maturation of female Atlantic salmon
(Ph.D.) Department of Zoology/Zoophysiology, Göteborg University, Box 463, SE-405 30 Göteborg, Sweden The 3D structure of

bovine somatotropin Bovine somatotropin or bovine somatotrophin (abbreviated bST and BST), or bovine growth hormone (BGH), is a peptide hormone produced by cows' pituitary glands. Like other hormones, it is produced in small quantities and is used in regulating ...

has been predicted using a combination of heuristics and energy minimisation.

Human peptides from this family

CSH1 Human placental lactogen (hPL), also called human chorionic somatomammotropin (HCS), is a polypeptide placental hormone, the human form of placental lactogen ( chorionic somatomammotropin). Its structure and function are similar to those of hum ...

; CSH2; CSHL1; GH1; GH2 (hGH-V); PRL;

References

{{InterPro content, IPR001400 Protein domains Hormones of the somatotropic axis