Sivelestat Scheme on:
[Wikipedia]
[Google]
[Amazon]
Sivelestat (
INN
Inns are generally establishments or buildings where travelers can seek lodging, and usually, food and drink. Inns are typically located in the country or along a highway; before the advent of motorized transportation they also provided accommo ...
, research name ONO 5046, marketed as Elaspol) is an inhibitor of human neutrophil elastase.
It is used in the treatment of acute respiratory failure and preliminary studies show it may also improve neuropathic pain.
Synthesis
Sivelestat is synthesised as follows:
References
Benzamides Hydrolase inhibitors Sulfonamides Pivalate esters {{respiratory-system-drug-stub