Simplicius may refer to:
; Persons
*
Pope Simplicius
Pope Simplicius (died 2 or 10 March 483) was the bishop of Rome from 468 to his death. He combated the Eutychian heresy, ended the practice of consecrating bishops only in December, and sought to offset the effects of Germanic invasions.
Electi ...
(d. 483 AD)
*
Simplicius of Cilicia
Simplicius of Cilicia (; el, Σιμπλίκιος ὁ Κίλιξ; c. 490 – c. 560 AD) was a disciple of Ammonius Hermiae and Damascius, and was one of the last of the Neoplatonists. He was among the pagan philosophers persecuted by Justinian i ...
(d. c. 560 AD), philosopher
* Saint Simplicius, legendary 'founding' bishop of the Sardinian
Diocese of Civita
*
Simplicius, Constantius and Victorinus
Simplicius, Constantius and Victorinus (''Victorian(us)'') ( it, Simplicio, Costanzo e Vittoriano) are venerated as Christian martyrs of the 2nd century.Benedictine Monks, ''Book of the Saints'' (Kessinger Publishing, 2003), 246. Simplicius, was, ...
(fl. 2nd century), Roman martyrs and saints
*
Simplicius, Faustinus and Beatrix
Saints Simplicius, Faustinus and Beatrix (or ''Beatrice, Viatrix'') were siblings martyred in Rome during the Diocletian persecution (302 or 303).
Legend
The legend about them is that the brothers Simplicius and Faustinus were cruelly tortured on ...
(d. 302 or 303 AD), Roman martyrs and saints
; Art and fiction
* ''
Simplicius Simplicissimus
''Simplicius Simplicissimus'' (german: link=no, Der abenteuerliche Simplicissimus Teutsch) is a picaresque novel of the lower Baroque style, written in 1668 by Hans Jakob Christoffel von Grimmelshausen and probably published the same year (althou ...
'', a picaresque novel about the character of the same name
*
''Simplicius'' (operetta), an operetta by Johann Strauss II
* A character in ''
Dialogue Concerning the Two Chief World Systems'', a 1632 work by Galileo
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