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Silent Spring Institute is a nonprofit organization dedicated to studying and reporting primarily on breast cancer prevention, although its research covers other health-related topics as well.


Founding and purpose

The nonprofit organization was founded in 1994 "as an outgrowth of the Massachusetts Breast Cancer Coalition."Cynthia McCormick, "Silent Spring Institute Seeks More State Support," ''Cape Cod Times,'' October 20, 2014
/ref> It engages in research on the links between risk of breast cancer and exposure to chemicals found in everyday products."Newton's Silent Spring Institute Celebrates 20th Anniversary," ''Wicked Local Newton,'' November 28, 2014
/ref> Its scientific team does field testing on
Cape Cod Cape Cod is a peninsula extending into the Atlantic Ocean from the southeastern corner of mainland Massachusetts, in the northeastern United States. Its historic, maritime character and ample beaches attract heavy tourism during the summer mont ...
and collaborates with private and academic laboratories. In 2014 the ''
Cape Cod Times The ''Cape Cod Times'' is a broadsheet daily newspaper serving Barnstable County, Massachusetts, United States, which encompasses 15 towns on Cape Cod with a year-round population of about 230,000. It is owned by Gannett, which also owns several ...
'' recalled that:
From the start, Silent Spring Institute researchers were interested in whether environmental toxins were having a particular influence on the Cape's drinking water, which is served by a sole source aquifer and leaches through sandy soil that in theory allows wastewater – and contaminants – to drain into the water supply more quickly than through other types of soil. Silent Spring researchers have tested water in public and private wells for the presence of chemicals known as emerging contaminants and have visited scores of Cape homes to measure for the presence of hormone-disrupting chemicals.
Based in
Newton, Massachusetts Newton is a city in Middlesex County, Massachusetts, United States. It is approximately west of downtown Boston. Newton resembles a patchwork of thirteen villages, without a city center. According to the 2020 U.S. Census, the population of Ne ...
,"Scientists Identify Toxic Chemicals Women Should Avoid to Prevent Breast Cancer," ''Healthline News,'' May 13, 2014
/ref> the institute was named in honor of environmentalist
Rachel Carson Rachel Louise Carson (May 27, 1907 – April 14, 1964) was an American marine biologist, writer, and conservationist whose influential book ''Silent Spring'' (1962) and other writings are credited with advancing the global environmental m ...
, who died of
breast cancer Breast cancer is cancer that develops from breast tissue. Signs of breast cancer may include a lump in the breast, a change in breast shape, dimpling of the skin, milk rejection, fluid coming from the nipple, a newly inverted nipple, or a re ...
.Trevor Butterworth, "BPA A Concern For Breast Cancer? Not According To Study By Leading Environmental Group," ''Forbes'', June 12, 2014
/ref>


Research


Background

The only independent research institute dedicated to studying breast cancer prevention, Silent Spring Institute has established a reputation for exemplary research. In keeping with Silent Spring's commitment to collaboration between scientists and activists, researchers report individual exposure results to all individuals and communities participating in its studies. It has become a pioneer in developing ethical methods for communicating results when the health implications are uncertain. In 2000, Silent Spring's research was honored with a
U.S. Environmental Protection Agency The Environmental Protection Agency (EPA) is an independent executive agency of the United States federal government tasked with environmental protection matters. President Richard Nixon proposed the establishment of EPA on July 9, 1970; it be ...
Environmental Merit Award. The papers of Silent Spring Institute from 1988 to 2006 are archived at the
Schlesinger Library The Arthur and Elizabeth Schlesinger Library on the History of Women in America is a research library at the Radcliffe Institute for Advanced Study, Harvard University. According to Nancy F. Cott, the Carl and Lily Pforzheimer Foundation Director, ...
at Harvard, which has prepared a detailed finding aid.


Projects

* The institute partnered with the
Lawrence Berkeley National Laboratory Lawrence Berkeley National Laboratory (LBNL), commonly referred to as the Berkeley Lab, is a United States Department of Energy National Labs, United States national laboratory that is owned by, and conducts scientific research on behalf of, t ...
in a research project on "Chemicals and Breast Cancer: Building on National Initiatives for Chemical Safety Screening," which focused on the development of rapid ''
in vitro ''In vitro'' (meaning in glass, or ''in the glass'') studies are performed with microorganisms, cells, or biological molecules outside their normal biological context. Colloquially called "test-tube experiments", these studies in biology an ...
'' screens for breast carcinogens in
mammary A mammary gland is an exocrine gland in humans and other mammals that produces milk to feed young offspring. Mammals get their name from the Latin word ''mamma'', "breast". The mammary glands are arranged in organs such as the breasts in primat ...
cells. A report was published in 2014.Jennifer McPartland, Heather C. Dantzker and Christopher J. Portier, "Building a Robust 21st Century Chemical Testing Program at the U.S. Environmental Protection Agency: Recommendations for Strengthening Scientific Engagement," ''Environmental Health Perspectives,'' October 24, 2014
/ref> * Researchers from the institute and from the
University of Antwerp The University of Antwerp ( nl, Universiteit Antwerpen) is a major Belgian university located in the city of Antwerp. The official abbreviation is ''UA'', but ''UAntwerpen'' is more recently used. The University of Antwerp has about 20,000 stud ...
, Belgium, reported in 2014 that there had been "limited information" about Americans' exposure to phosphate
flame retardants The term flame retardants subsumes a diverse group of chemicals that are added to manufactured materials, such as plastics and textiles, and surface finishes and coatings. Flame retardants are activated by the presence of an ignition source a ...
and how such exposure might affect their health, so in 2011 a
urine analysis A urine test is any medical test performed on a urine specimen. The analysis of urine is a valuable diagnostic tool because its composition reflects the functioning of many body systems, particularly the kidneys and urinary system, and specimens a ...
and study was made of sixteen California residents, and all were found to have traces of three harmful chemicals – bis-(1,3-dichloro-2-propyl) phosphate ( BDCIPP), tris-(1,3-dichloro-isopropyl) phosphate ( TDCIPP) and bis-(2-chloroethyl) phosphate ( BCEP). :The lead researcher, the institute's Robin Dodson, said: "We found that several toxic
flame retardants The term flame retardants subsumes a diverse group of chemicals that are added to manufactured materials, such as plastics and textiles, and surface finishes and coatings. Flame retardants are activated by the presence of an ignition source a ...
are in people's bodies. When you sit on your couch, you want to relax, not get exposed to chemicals that may cause
cancer Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. These contrast with benign tumors, which do not spread. Possible signs and symptoms include a lump, abnormal b ...
. ''Medical News Today'' said that "Flame retardant chemicals are found in a variety of products that we come into contact with every day, such as
carpets A carpet is a textile floor covering typically consisting of an upper layer of pile attached to a backing. The pile was traditionally made from wool, but since the 20th century synthetic fibers such as polypropylene, nylon, or polyester have ...
, sofas, curtains and even baby products. The chemicals were introduced to these products in the 1970s to reduce the likelihood of ignitability." It noted that another chemical, tris-(2-chloroethyl) phosphate (
TCEP TCEP (tris(2-carboxyethyl)phosphine) is a reducing agent frequently used in biochemistry and molecular biology applications. It is often prepared and used as a hydrochloride salt (TCEP-HCl) with a molecular weight of 286.65 gram/mol. It is solub ...
), "known to cause cancer and reproductive problems in humans," was found in about 75% if the subjects and that it had "never before been discovered in Americans." ''Counsel and Health'' noted that "The team also found that residents with the highest levels of TCEP and TDCIPP in their urine lived in homes that had respective chemical in dust, which suggests that the home and the furniture in it are exposing people to toxic flame retardants."Honor Whiteman, "Researchers Discover Type of Toxic Flame Retardant in Americans for First Time," ''Medical News Today,'' November 15, 2014
/ref>
/ref> ttps://www.sciencedaily.com/releases/2014/11/141112084506.htm A Previously Unrecognized Flame Retardant Found in Americans for the First Time, ''Science Daily,'' November 12, 2014/ref> :''Medical News Today'' concluded: :
The researchers note that there are strategies consumers can adopt to reduce their exposure to toxic flame retardants. Because the chemicals are likely to gather in dust, they recommend that individuals use a
vacuum A vacuum is a space devoid of matter. The word is derived from the Latin adjective ''vacuus'' for "vacant" or "void". An approximation to such vacuum is a region with a gaseous pressure much less than atmospheric pressure. Physicists often dis ...
with a high-efficiency particulate air (HEPA) filter to vacuum their homes. This filter traps particles, rather than recirculate them back into the air. They also recommend that people throw away any foam that is deteriorating in their households, as it is possible such products may emit higher levels of toxic chemicals.
:The study was published in the journal ''
Environmental Science & Technology ''Environmental Science & Technology'' is a biweekly peer-reviewed scientific journal published since 1967 by the American Chemical Society. It covers research in environmental science and environmental technology, including environmental policy. ...
.'' * Early in 2014 the institute published a paper in ''
Environmental Health Perspectives ''Environmental Health Perspectives'' (''EHP'') is a peer-reviewed Peer review is the evaluation of work by one or more people with similar competencies as the producers of the work (peers). It functions as a form of self-regulation by qua ...
'' that listed "17 types of chemicals to avoid, including those in
gasoline Gasoline (; ) or petrol (; ) (see ) is a transparent, petroleum-derived flammable liquid that is used primarily as a fuel in most spark-ignited internal combustion engines (also known as petrol engines). It consists mostly of organic co ...
,
diesel exhaust Diesel exhaust is the gaseous exhaust produced by a diesel type of internal combustion engine, plus any contained particulates. Its composition may vary with the fuel type or rate of consumption, or speed of engine operation (e.g., idling or at ...
, flame retardants and
paint thinner A paint thinner is a solvent used to thin oil-based paints. Solvents labeled "paint thinner" are usually mineral spirits having a flash point at about 40 °C (104 °F), the same as some popular brands of charcoal starter. Common solven ...
." ''Forbes'' magazine called the paper a "massive synthesis of data from the
National Toxicology Program The National Toxicology Program (NTP) is an inter-agency program run by the United States Department of Health and Human Services to coordinate, evaluate, and report on toxicology within public agencies. The National Toxicology Program is headqua ...
and consensus reports from international cancer authorities" which "identified 102 chemicals as critical for breast cancer research and prevention." The institute said the study was "a road map for breast cancer prevention by identifying high-priority chemicals and evaluating tools to measure exposure." :In 2014, Silent Spring published
list of 100 breast carcinogens
with widespread exposure and identified methods to measure them in people, providing a road map for breast cancer research and policies to reduce exposure. :The authors of the study were Ruthann A. Rudel, Janet M. Ackerman and Julia Green Brody of the Silent Spring Institute and Kathleen R. Attfield of the
Harvard School of Public Health The Harvard T.H. Chan School of Public Health is the public health school of Harvard University, located in the Longwood Medical Area of Boston, Massachusetts. The school grew out of the Harvard-MIT School for Health Officers, the nation's first ...
.
United Press International United Press International (UPI) is an American international news agency whose newswires, photo, news film, and audio services provided news material to thousands of newspapers, magazines, radio and television stations for most of the 20th ...
summed up its results by stating: "Gasoline and chemicals formed by combustion from vehicles, lawn equipment, smoking and charred food are among the largest sources of mammary carcinogens in the environment."Alex Cukin, "Study: Everyday Chemicals That May Increase Breast Cancer Risk," United Press International, May 13, 2014
/ref> In detail, these carcinogens included: :
Solvents, such as
methylene chloride Dichloromethane (DCM or methylene chloride, methylene bichloride) is an organochlorine compound with the formula . This colorless, volatile liquid with a chloroform-like, sweet odour is widely used as a solvent. Although it is not miscible with ...
and other
halogenated In chemistry, halogenation is a chemical reaction that entails the introduction of one or more halogens into a compound. Halide-containing compounds are pervasive, making this type of transformation important, e.g. in the production of polyme ...
organic solvents used in spot removers, specialty cleaners and industrial degreasers. Pharmaceutical hormones such as hormone replacement therapy; certain flame retardants used in furniture; a chemical used in stain-resistant textiles and non-stick coatings; and styrene found in tobacco smoke and also used to make Styrofoam. Drinking water. It can contain mammary carcinogens, such disinfection by-products or solvents.
* In 2013 the ''
Science of the Total Environment ''Science of the Total Environment'' is a weekly international peer-reviewed scientific journal covering environmental science. It was established in 1972 and is published by Elsevier. The editors-in-chief are Damià Barceló (Consejo Superior de I ...
'' journal published a study led by institute scientist Laurel Schaider that "looked at emerging contaminants in
septic systems A septic tank is an underground chamber made of concrete, fiberglass, or plastic through which domestic wastewater ( sewage) flows for basic sewage treatment. Settling and anaerobic digestion processes reduce solids and organics, but the treat ...
" on Cape Cod and their impact on water wells. It found that "
Caffeine Caffeine is a central nervous system (CNS) stimulant of the methylxanthine class. It is mainly used recreationally as a cognitive enhancer, increasing alertness and attentional performance. Caffeine acts by blocking binding of adenosine t ...
and
acetaminophen Paracetamol, also known as acetaminophen, is a medication used to treat fever and mild to moderate pain. Common brand names include Tylenol and Panadol. At a standard dose, paracetamol only slightly decreases body temperature; it is inferior ...
were very well removed" by sewage treatment but "Not so well removed were an antibiotic containing sulfa, and
PFOS Perfluorooctanesulfonic acid (PFOS) (conjugate base perfluorooctanesulfonate) is a chemical compound having an eight-carbon fluorocarbon chain and a sulfonic acid functional group and thus a perfluorosulfonic acid. It is an anthropogenic (man ...
, a chlorinated flame retardant commonly used in a number of home stain-resistant and nonstick coatings, as well as firefighting foams." It was "estimated that 80–85 percent of nitrogen comes from human waste not being properly processed via the Cape’s septic systems."Kathleen Szmit, "What's in Your Water?" ''The Barnstable Patriot,'' September 20, 2013
* A study by the institute, reported in 2012, found that a test of 50 household products such as cleaners,
cosmetics Cosmetics are constituted mixtures of chemical compounds derived from either natural sources, or synthetically created ones. Cosmetics have various purposes. Those designed for personal care and skin care can be used to cleanse or protect ...
and personal-care products found a "troubling amount" of "potentially harmful" products. Julia Brody of the institute advised consumers to avoid "antimicrobial products like some hand sanitizers and soaps" and "many products that contain fragrances." According to a television news report, "Silent Spring says look for '
paraben Parabens are a class of widely used preservatives in cosmetic and pharmaceutical products. Chemically, they are a series of parahydroxybenzoates or esters of parahydroxybenzoic acid (also known as 4-hydroxybenzoic acid). Parabens are effective p ...
-free' products when shopping for deodorant, shampoo or cosmetics, and avoid vinyl products especially pillow and mattress protectors. The problem, the study finds, is that manufacturers are not required to list all ingredients."Kate Merrill, "Study: Harmful Chemicals Left Off Household Product Labels," CBS Boston: WBZ News Radio, March 8, 2012
/ref> : Industry groups responded quickly and negatively: The International Fragrance Association of North America said the study was "an example of biased, advocacy based research," and the
Personal Care Products Council The Personal Care Products Council (PCPC) is an American trade association. The PCPC was founded in 1894 as the Manufacturing Perfumers' Association, renamed the American Manufacturers of Toilet Articles (AMTA) in 1922, and renamed again as the C ...
said that "equating the mere presence of chemicals in products with potential harm is wrong and needlessly scares consumers." *In 2007, Silent Spring published a database of 216 chemicals that cause mammary gland tumors in animal studies. Dubbed "the breast cancer list" by ''Science'' magazine, the study made headlines by highlighting new hypotheses about environmental risks and showing that common exposures, including diesel and
benzene Benzene is an organic chemical compound with the molecular formula C6H6. The benzene molecule is composed of six carbon atoms joined in a planar ring with one hydrogen atom attached to each. Because it contains only carbon and hydrogen atoms, ...
in gasoline, were biologically plausible links to breast cancer. * In its first decade, the research team focused on identifying biologically suspect chemicals and measuring personal exposure. Silent Spring's 2003 Household Exposure Study (HES) was the first and most comprehensive assessment of
endocrine disruptor Endocrine disruptors, sometimes also referred to as hormonally active agents, endocrine disrupting chemicals, or endocrine disrupting compounds are chemicals that can interfere with endocrine (or hormonal) systems. These disruptions can cause c ...
s in homes; it documented consumer products as the primary source of the chemicals. * Silent Spring began by investigating the links between hormone disruptors and human health among women on Cape Cod. The study, published in 2004, showed that the longer that women lived on Cape Cod, the higher was their breast cancer risk.McKelvey, W., J.G. Brody, A. Aschengrau, and C.H. Swartz (2004) "Association between Residence on Cape Cod, Massachusetts, and Breast Cancer", in ''Annals of Epidemiology'', 14 (2), pp.89–94


Other activities

The organization celebrated its twentieth anniversary on October 20, 2014, with a fund-raising dinner at the Royal Sonesta Hotel in Cambridge, Massachusetts. Speakers included ''New York Times'' journalist
Nicholas Kristof Nicholas Donabet Kristof (born April 27, 1959) is an American journalist and political commentator. A winner of two Pulitzer Prizes, he is a regular CNN contributor and an op-ed columnist for ''The New York Times''. Born in Chicago, Kristof was ...
, author Florence Williams and institute director Julia Brody. Ellen Parker of Newton, the chair of the institute's board, received its Rachel Carson Advocacy Award. Reporter Kelley Tuthill of radio station
WCVB WCVB-TV (channel 5) is a television station in Boston, Massachusetts, United States, affiliated with ABC and owned by Hearst Television. The station's studios are located on TV Place (off Gould Street near the I-95/ MA 128/Highland Avenue int ...
was the master of ceremonies.


Leadership

In late 2014 Julia Brody was executive director, and Cynthia Barakatt was chair of the
board Board or Boards may refer to: Flat surface * Lumber, or other rigid material, milled or sawn flat ** Plank (wood) ** Cutting board ** Sounding board, of a musical instrument * Cardboard (paper product) * Paperboard * Fiberboard ** Hardboard, a ty ...
. Ellen Calmas was a board member.


Funding

During the seven years after its founding in 1995, the institute received $8.5 million in state grants, but as it prepared to celebrate its 20th anniversary in 2014, state support had vanished and no help at all was granted in the state budget that year. Nor had it been granted in the 2010, 2011 or 2012 fiscal years. Speaking about the falloff in appropriations, Representative Randy Hunt of
Sandwich A sandwich is a food typically consisting of vegetables, sliced cheese or meat, placed on or between slices of bread, or more generally any dish wherein bread serves as a container or wrapper for another food type. The sandwich began as a po ...
said, according to the ''Cape Cod Times,'' that "some people associated with Silent Spring hav
raised hackles
" Hunt was quoted as saying that Silent Spring "activists" had been known to "denigrate anyone who they don't feel is pushing for their cause as hard as they want." The ''Times'' quoted co-founder Cheryl Osimo as responding, "I understand perhaps my passion can be misunderstood as abrasive." She said the loss of funds was caused by a "difficult economy," resulting in an increased need for private donations.
Sylvia Connor of East Sandwich, a breast cancer survivor and Silent Spring volunteer, said . . . that she and other survivors feel strongly about continuing the work of the research institute. She said ... it was a "slap in the face" to see
tate Representative Tate is an institution that houses, in a network of four art galleries, the United Kingdom's national collection of British art, and international modern and contemporary art. It is not a government institution, but its main sponsor is the U ...
Brian Mannal join forces with actor
Mark Ruffalo Mark Alan Ruffalo (; born November 22, 1967) is an American actor and producer best known for playing Bruce Banner / Hulk since 2012 in the superhero franchise of the Marvel Cinematic Universe, and in the television series '' She-Hulk: Attorne ...
on his Water Defense organization at a time when Silent Spring has been doing without state funds.


References


Further reading



Jeanne Rizzo and Julia Brody, "50 Years After Rachel Carson," ''The Huffington Post'', April 29, 2014

"Contaminants Pervasive In Cape Cod's Drinking Water Supply, Silent Spring Institute Finds," Water Online, September 18, 2013


External links

*
Records of Silent Spring Institute, 1970-2011: A Finding Aid.Schlesinger Library
Radcliffe Institute, Harvard University. {{authority control 1994 establishments in Massachusetts Breast cancer organizations Newton, Massachusetts Medical and health organizations based in Massachusetts Organizations established in 1994