N-acetylneuraminate epimerase (, ''sialic acid epimerase'', ''N-acetylneuraminate mutarotase'', sialic acid mutarotase, ''YjhT'', NanM) is an
enzyme
Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products. A ...
with
systematic name A systematic name is a name given in a systematic way to one unique group, organism, object or chemical substance, out of a specific population or collection. Systematic names are usually part of a nomenclature.
A semisystematic name or semitrivial ...
''N-acetyl-alpha-neuraminate 2-epimerase''.
This enzyme
catalyses the following
chemical reaction
A chemical reaction is a process that leads to the IUPAC nomenclature for organic transformations, chemical transformation of one set of chemical substances to another. Classically, chemical reactions encompass changes that only involve the pos ...
: ''N''-acetyl-alpha-neuraminate
''N''-acetyl-beta-neuraminate
Sialoglycoconjugates present in vertebrates are linked exclusively by alpha-linkages.
See also
*
sialic acid Sialic acids are a class of alpha-keto acid sugars with a nine-carbon backbone.
The term "sialic acid" (from the Greek for saliva, - ''síalon'') was first introduced by Swedish biochemist Gunnar Blix in 1952. The most common member of this gr ...
**
''N''-acetylneuraminate
*
Mutarotation Mutarotation is the change in the ''optical rotation'' because of the change in the equilibrium between two anomers, when the corresponding stereocenters interconvert. Cyclic sugars show mutarotation as α and β anomeric forms interconvert.
The op ...
References
External links
*
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