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Sheridan Gray Snyder OBE (born October 20, 1936) is an entrepreneur,
venture capitalist Venture capital (often abbreviated as VC) is a form of private equity financing that is provided by venture capital firms or funds to startups, early-stage, and emerging companies that have been deemed to have high growth potential or which hav ...
, and
philanthropist Philanthropy is a form of altruism that consists of "private initiatives, for the Public good (economics), public good, focusing on quality of life". Philanthropy contrasts with business initiatives, which are private initiatives for private goo ...
in the
biotechnology Biotechnology is the integration of natural sciences and engineering sciences in order to achieve the application of organisms, cells, parts thereof and molecular analogues for products and services. The term ''biotechnology'' was first used b ...
industry. He is the founder and CEO of Biocatalyst, but also a "serial entrepreneur", a founder of
Genzyme Genzyme was an American biotechnology company based in Cambridge, Massachusetts. Since its acquisition in 2011, Genzyme (also known as Genzyme Transgenics Corp or GTC Biotherapeutics) has been a fully owned subsidiary of Sanofi. In 2010, Genzyme ...
and many other companies. Snyder, who was the University of Virginia's best tennis player when he was studying for his BA in French and Romance Languages there in the 1960s, made "major contributions to the popularisation of tennis in the USA." He co-founded the National Junior Tennis League that reaches 250,000 inner-city young people and constructed a new tennis center at the
University of Virginia The University of Virginia (UVA) is a Public university#United States, public research university in Charlottesville, Virginia. Founded in 1819 by Thomas Jefferson, the university is ranked among the top academic institutions in the United S ...
.


Beginnings


Education

Snyder graduated from
The Lawrenceville School The Lawrenceville School is a coeducational preparatory school for boarding and day students located in the Lawrenceville section of Lawrence Township, in Mercer County, New Jersey, United States. Lawrenceville is a member of the Eight Scho ...
in New Jersey and is a 1958 graduate of
The University of Virginia The University of Virginia (UVA) is a public research university in Charlottesville, Virginia. Founded in 1819 by Thomas Jefferson, the university is ranked among the top academic institutions in the United States, with highly selective adm ...
with a Bachelor of Arts in French & Romance Languages. At UVa, Snyder was a member of the SPE social fraternity. Snyder received an Honorary Doctorate of Law degree from the
University of Dundee The University of Dundee; . Abbreviated as ''Dund.'' for post-nominals. is a public university, public research university based in Dundee, Scotland. It was founded as a University college#United Kingdom, university college in 1881 with a donation ...
in 2002.


Early Business Career

Upon graduation from UVA, Snyder began his career as a Credit Analyst for New York Trust Corporation.


Venture capitalist

Ed Glassmeyer, Senior Manager of the venture capital firm Oak Partners, funded many of Snyder's early start-up companies, mainly in electronics. Glassmeyer, a Princeton graduate, began in venture capitalism in 1968 to 1970 at CitiCorp Venture Capital. By 1978 he co-founded Oak Investment Partners with Stewart Greenfield and became Managing Partner.


Cambridge Machine Corporation

Snyder's start-up Cambridge Machine Corporation, initiated the development and invention of high-speed mailing/envelope inserting machines. By 1970 Snyder had sold Cambridge Machine Corporation to
Pitney-Bowes Pitney Bowes Inc. is an American technology company most known for its postage meters and other mailing equipment and services, and with expansions into e-commerce, software, and other technologies. The company was founded by Arthur Pitney, who i ...
and he began working for them as National Sales Account manager.


Instapak

In 1971, Snyder founded a start-up packaging company, Instapak, funded by venture capitalist, Ed Glassmeyer. Instapak markets "foam-in-place packaging"—revolutionary for its time— that creates a protective barrier for heavy, fragile instrumentation and computer systems. Instapak is now the largest division of Sealed Air Corporation (NYSE: SEE), with more than 5,500 employees and revenues of $1 billion.


Biotechnology

In 1981, Glassmeyer's entry into the then-embryonic biotechnology industry by starting up Genzyme—a biotechnology firm—was in response to Glassmeyer's challenge.


Genzyme

In its earliest moments "Genzyme was just really the combination" of Snyder and Henry Blair, a technician at the New England Enzyme Center at Tufts Medical School, who had worked for
Roscoe Brady Roscoe Owen Brady (October 11, 1923 – 13 June 2016) was an American biochemist. He attended the Pennsylvania State University and obtained his M.D. degree from Harvard Medical School in 1947. He interned at the Hospital of the University of P ...
at the
National Institute of Health The National Institutes of Health, commonly referred to as NIH (with each letter pronounced individually), is the primary agency of the United States government responsible for biomedical and public health research. It was founded in the late ...
(NIH). According to Snyder, he and Blair "started developing a business on our own." Blair had a contract with the
National Institutes of Health The National Institutes of Health, commonly referred to as NIH (with each letter pronounced individually), is the primary agency of the United States government responsible for biomedical and public health research. It was founded in the late ...
(NIH) to produce modified enzymes for the NIH and test it in clinical trials. Roscoe and his colleagues had been working on a treatment for
Gaucher's disease Gaucher's disease or Gaucher disease () (GD) is a genetic disorder A genetic disorder is a health problem caused by one or more abnormalities in the genome. It can be caused by a mutation in a single gene (monogenic) or multiple genes (polyg ...
for over a decade at that time. Snyder was transformed by the idea that entrepreneurs could "actually help people and save some lives." Genzyme's first office was an old clothing warehouse adjacent to Tufts Medical School. Snyder served as Genzyme's first Chairman, President and CEO until
Henri Termeer Henri A. Termeer (February 28, 1946 – May 12, 2017) was a Dutch biotechnology executive and entrepreneur who is considered a pioneer in corporate strategy in the biotechnology industry for his tenure as CEO at Genzyme. Termeer created a busine ...
was appointed as CEO in 1985. In 1988 Termeer took over as Genzyme's Chairman. By 1983 Genzyme interviewed Baxter employee Henri Termeer, who had completed his MBA at Snyder's alma mater, the
University of Virginia The University of Virginia (UVA) is a Public university#United States, public research university in Charlottesville, Virginia. Founded in 1819 by Thomas Jefferson, the university is ranked among the top academic institutions in the United S ...
in 1973. By that time Genzyme had seventeen employees who worked in an old clothing warehouse adjacent to Tufts Medical School. Genzyme also had a small diagnostics operation in England. ;Bio Information Associates (BIA) By 1983 Genzyme developed close ties with a group of entrepreneurial professors from MIT and Harvard. These "well-known, full professors who had a lot of multidisciplinary post-docs" had formed a successful Boston-based business management consulting firm a Bio Information Associates (BIA) in 1980. Oral history conducted by Ted Everson, Jennifer Dionisio, Pei Koay, and Arnold Thackray, May 23, December 7, 2006, August 2, 2007, December 18, 2008 & September 30, 2011 As Termeer described it, "Genzyme was just these professors from MIT and myself and some venture capitalists." as told to Scott Helman One of these professors was a
Harvard Harvard University is a private Ivy League research university in Cambridge, Massachusetts. Founded in 1636 as Harvard College and named for its first benefactor, the Puritan clergyman John Harvard, it is the oldest institution of higher le ...
chemistry professor,
George M. Whitesides George McClelland Whitesides (born August 3, 1939) is an American chemist and professor of chemistry at Harvard University. He is best known for his work in the areas of nuclear magnetic resonance spectroscopy, organometallic chemistry, molecu ...
who founded many companies. He is considered to be Genzyme's co-founder. In 1986, Snyder initiated the first sale of Genzyme stock shares (Initial Public Offering). "In the formative years of biotechnology, Genzyme was the industry’s Apple, blazing a pathway for creating protein-based treatments for rare diseases." Genzyme’s business focused on enzyme deficiency diseases. It first produced diagnostic enzymes for victims of Gaucher's disease, a rare chronic disorder causing enormous enlargement of the spleen, a change in skin pigmentation and bone lesions. It afflicts 10,000 young Hasidic Jews each year. It currently employs 10,000 people worldwide, with approximately $3.6 billion in revenues, with a market valuation of $20 billion. Genzyme (NASDAQ:GENZ) is the largest private employer in Boston, Massachusetts.


Biotage

Snyder founded
Biotage Pyrosequencing is a method of DNA sequencing (determining the order of nucleotides in DNA) based on the "sequencing by synthesis" principle, in which the sequencing is performed by detecting the nucleotide incorporated by a DNA polymerase. Pyroseq ...
in 1989 which focuses on the development of novel drug development systems. Biotage was acquired by the Swedish biotechnology company Pyrosequencing in 2004 which then took the nam
Biotage AB


Upstate

In 1994 Snyder founded Argonex a small biotech start-up in
Charlottesville, Virginia Charlottesville, colloquially known as C'ville, is an independent city in the Commonwealth of Virginia. It is the county seat of Albemarle County, which surrounds the city, though the two are separate legal entities. It is named after Queen Ch ...
. In 1996, Snyder founded and served as chairman and chief executive officer of Upstate Biotechnology Incorporated, merging it with Argonex. Upstate Inc. develops cell signaling products, technology platforms and services. Upstate was sold to Serologicals Corporation in 2004 for $205 million.


BioCatalyst International

In 2005 Snyder founded Biocatalyst International, to create biotech firms in partnership with scientists, such as Xcovery, which he co-founded with Chris Liang, Director of Medicinal Chemistry, Scripps Research Florida, and co-developer of Sutent,
Pfizer Pfizer Inc. ( ) is an American multinational pharmaceutical and biotechnology corporation headquartered on 42nd Street in Manhattan, New York City. The company was established in 1849 in New York by two German entrepreneurs, Charles Pfizer ...
’s first small molecule oncology drug. Molecular MD was co-founded with
Brian Druker Brian J. Druker (born April 30, 1955) is a physician-scientist at Oregon Health & Science University, in Portland, Oregon. He is the director of OHSU's Knight Cancer Institute, Jeld-Wen Chair of Leukemia Research, and professor of medicine. In 2 ...
, inventor of
Gleevec Imatinib, sold under the brand names Gleevec and Glivec (both marketed worldwide by Novartis) among others, is an oral chemotherapy medication used to treat cancer. Imatinib is a small molecule inhibitor targeting multiple receptor tyrosine kin ...
, director of the cancer center at the Oregon Health Sciences University in Portland. Oregon. Gleevec is a small-molecule drug that prevents and stops the growth of cancer cells in chronic myeloid leukemia (CML). MMD is a molecular diagnostic company developing personalized medicine utilizing sensitive detection systems.


Awards

In 1999, the
State of Virginia Virginia, officially the Commonwealth of Virginia, is a state in the Mid-Atlantic and Southeastern regions of the United States, between the Atlantic Coast and the Appalachian Mountains. The geography and climate of the Commonwealth are s ...
honored Snyder with its Biotechnology Lifetime Achievement Award. In 2003, he was appointed to Scotland’s International Advisory Board and serves as an advisor to the Scottish government on the development of its biotech sector. In this capacity, Snyder played a role with the development of an bioscience translational center outside Edinburgh. Snyder was honored OBE (Officer of the Order of the British Empire) in 2005 by HM Queen
Elizabeth II of the United Kingdom Elizabeth II (Elizabeth Alexandra Mary; 21 April 1926 – 8 September 2022) was Queen of the United Kingdom and other Commonwealth realms from 6 February 1952 until her death in 2022. She was queen regnant of 32 sovereign states during h ...
on the advice of the British government.


Board of directors

He is a member of the board of trustees – along with William C. Battle, Arthur Garson Jr, William Black, Sheridan G. Snyder, Patricia J. Edgerton, Aaron Shatkin and Robert W. Battle – of the Ivy Charitable Foundation, which was created in 2000 and has been a benefactor of the University of Virginia's biomedical programs. In 2005 the Ivy Charitable Foundation donated "$45 million to the University of Virginia Health System to expand laboratory space for biomedical research and to speed the translation of new discoveries into effective treatments and cures." This gift was used to construct a new Children's Hospital, the Emily Couric Cancer Center and the Sheridan G. Snyder Translational Research Center.Sheridan G. Snyder Translational Research Building - http://www.virginia.edu/vpr/snyder_building.html


Philanthropy


Tennis

Snyder funded and developed the National Junior Tennis League (NJTL), along with the encouragement and support of
Arthur Ashe Arthur Robert Ashe Jr. (July 10, 1943 – February 6, 1993) was an American professional tennis player who won three Grand Slam singles titles. He started to play tennis at six years old. He was the first black player selected to the Un ...
and
Charles Pasarell Charles Manuel Pasarell Jr. (born February 12, 1944) is a Puerto Rican former tennis player, tennis administrator and founder of the current Indian Wells tournament. He has also commented for the Tennis Channel and with Arthur Ashe and Sheridan ...
. Snyder supported the NJTL for 15 years. This organization now operates, through the USTA, in 110 cities and reaches 250,000 inner-city youths. In 1988, Snyder was the founder, chairman and CEO of Compuflo Inc., which developed a specialty high-end computer program used to analyze airflow to aid the design of aircraft and autos, a company donated to the University of Virginia to support its laboratories. Snyder also funded University Technology Corporation, where companies were formed with University of Virginia technology and the proceeds generated by these business ventures were donated back to the University. In 1995 Snyder contributed to the construction of a new tennis center at the University of Virginia which was named the Sheridan Snyder Tennis Center. In 2008 Snyder received the
Intercollegiate Tennis Association The Intercollegiate Tennis Association (ITA) is the governing body and coaches association of college tennis, both an advocate and authority, overseeing men’s and women’s varsity tennis at all levels – NCAA Division I, NCAA Division II, NC ...
Achievement Award for achievements outside the game of tennis.


References

{{DEFAULTSORT:Snyder, Sheridan 1936 births Living people People from Long Island University of Virginia alumni Lawrenceville School alumni