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Seth Franklin Berkley (born October 18, 1956) is an
American American(s) may refer to: * American, something of, from, or related to the United States of America, commonly known as the "United States" or "America" ** Americans, citizens and nationals of the United States of America ** American ancestry, pe ...
medical
epidemiologist Epidemiology is the study and analysis of the distribution (who, when, and where), patterns and risk factor, determinants of health and disease conditions in a defined population. It is a cornerstone of public health, and shapes policy decision ...
, the CEO of
Gavi, the Vaccine Alliance GAVI, officially Gavi, the Vaccine Alliance (previously the GAVI Alliance, and before that the Global Alliance for Vaccines and Immunization) is a public–private global health partnership with the goal of increasing access to immunization ...
and a global advocate of the power of vaccines. He is the founder and former president and CEO of the
International AIDS Vaccine Initiative The International AIDS Vaccine Initiative (IAVI) is a global not-for-profit, public-private partnership working to accelerate the development of vaccines to prevent HIV infection and AIDS. IAVI researches and develops vaccine candidates, conduct ...
(IAVI).


Early life and education

Berkley was born in
New York City New York, often called New York City or NYC, is the List of United States cities by population, most populous city in the United States. With a 2020 population of 8,804,190 distributed over , New York City is also the L ...
. In 1974, Berkley graduation from
McBurney School McBurney School was a boys college-preparatory school in Manhattan run by the YMCA of Greater New York. Its name commemorates Robert Ross McBurney, a prominent New York YMCA leader during the late 19th century. Among its alumni are actors Henry W ...
, a private school in
New York City New York, often called New York City or NYC, is the List of United States cities by population, most populous city in the United States. With a 2020 population of 8,804,190 distributed over , New York City is also the L ...
. In 1978, he received a ScB from
Brown University Brown University is a private research university in Providence, Rhode Island. Brown is the seventh-oldest institution of higher education in the United States, founded in 1764 as the College in the English Colony of Rhode Island and Providenc ...
. In 1981, he received a
M.D. Doctor of Medicine (abbreviated M.D., from the Latin ''Medicinae Doctor'') is a medical degree, the meaning of which varies between different jurisdictions. In the United States, and some other countries, the M.D. denotes a professional degree. T ...
from Brown University's
Alpert Medical School The Warren Alpert Medical School (formerly known as Brown Medical School, previously known as Brown University School of Medicine) is the medical school of Brown University, located in Providence, Rhode Island. Originally established in 1811, ...
. Berkley then trained in internal medicine at
Harvard University Harvard University is a private Ivy League research university in Cambridge, Massachusetts. Founded in 1636 as Harvard College and named for its first benefactor, the Puritan clergyman John Harvard, it is the oldest institution of higher le ...
.Seth Berkley Bio, IAVI Website


Career

From 1984 to 1986, Berkley worked as a medical epidemiologist for the Center for Infectious Diseases of the U.S.
Centers for Disease Control and Prevention The Centers for Disease Control and Prevention (CDC) is the national public health agency of the United States. It is a United States federal agency, under the Department of Health and Human Services, and is headquartered in Atlanta, Georgi ...
(CDC) in Atlanta, GA. While working for the
CDC The Centers for Disease Control and Prevention (CDC) is the national public health agency of the United States. It is a United States federal agency, under the Department of Health and Human Services, and is headquartered in Atlanta, Georgi ...
, Berkley was involved in, among other things, managing the national
Toxic Shock Syndrome Toxic shock syndrome (TSS) is a condition caused by bacterial toxins. Symptoms may include fever, rash, skin peeling, and low blood pressure. There may also be symptoms related to the specific underlying infection such as mastitis, osteomyeliti ...
surveillance system. He also conducted an investigation of an outbreak of Brazilian Purpuric Fever, a disease that was killing children in Brazil, and helped to discover the etiologic agent. In 1986, on assignment from the CDC, Berkley served as an epidemiologist for the
Massachusetts Department of Public Health The Massachusetts Department of Public Health is a governmental agency of the Commonwealth of Massachusetts with various responsibilities related to public health within that state. It is headquartered in Boston and headed by Commissioner Monica B ...
, working on routine surveillance and outbreak investigations. A year later, while working for the Carter Presidential Center in
Atlanta Atlanta ( ) is the capital and most populous city of the U.S. state of Georgia. It is the seat of Fulton County, the most populous county in Georgia, but its territory falls in both Fulton and DeKalb counties. With a population of 498,715 ...
, Berkley was assigned as an
epidemiologist Epidemiology is the study and analysis of the distribution (who, when, and where), patterns and risk factor, determinants of health and disease conditions in a defined population. It is a cornerstone of public health, and shapes policy decision ...
at the Ministry of Health in Uganda. In this role, he worked to establish and manage the Ugandan surveillance system for AIDS, validate the AIDS clinical case definition for Africa and assist with the conduct and analysis of the national HIV sero-survey. Berkley played a role in helping to develop Uganda's National AIDS Control programs, and served as an attending internal medicine physician at
Mulago Hospital Mulago National Specialised Hospital, also known as Mulago National Referral Hospital, is a component of Mulago Hospital Complex, the teaching facility of Makerere University College of Health Sciences. It is the largest public hospital in Ug ...
in
Kampala Kampala (, ) is the capital and largest city of Uganda. The city proper has a population of 1,680,000 and is divided into the five political divisions of Kampala Central Division, Kawempe Division, Makindye Division, Nakawa Division, and Ruba ...
. Subsequently, Berkley worked for the
Rockefeller Foundation The Rockefeller Foundation is an American private foundation and philanthropic medical research and arts funding organization based at 420 Fifth Avenue, New York City. The second-oldest major philanthropic institution in America, after the Carneg ...
, initially as program scientist and finally as associate director of the Health Sciences Division. During his eight years with the Rockefeller Foundation, Berkley managed programs in epidemiology,
public health Public health is "the science and art of preventing disease, prolonging life and promoting health through the organized efforts and informed choices of society, organizations, public and private, communities and individuals". Analyzing the det ...
, medical and nursing education, vaccination, AIDS and
sexually transmitted diseases Sexually transmitted infections (STIs), also referred to as sexually transmitted diseases (STDs) and the older term venereal diseases, are infections that are spread by sexual activity, especially vaginal intercourse, anal sex, and oral sex ...
and
reproductive health Sexual and reproductive health (SRH) is a field of research, healthcare, and social activism that explores the health of an individual's reproductive system and sexual wellbeing during all stages of their life. The term can also be further de ...
in Africa, Asia, and Latin America. Some of his initiatives included developing a public health training program, Public Health School without Walls, which began in Zimbabwe, Ghana, Uganda, and then spread to Vietnam, as well as an international program to support
non-governmental organizations A non-governmental organization (NGO) or non-governmental organisation (see spelling differences) is an organization that generally is formed independent from government. They are typically nonprofit entities, and many of them are active in h ...
working on AIDS, the International HIV/AIDS Alliance. He also represented the Rockefeller Foundation during meetings of the
United Nations The United Nations (UN) is an intergovernmental organization whose stated purposes are to maintain international peace and international security, security, develop friendly relations among nations, achieve international cooperation, and be ...
' Children's Vaccine Initiative, which was later replaced by
Gavi, the Vaccine Alliance GAVI, officially Gavi, the Vaccine Alliance (previously the GAVI Alliance, and before that the Global Alliance for Vaccines and Immunization) is a public–private global health partnership with the goal of increasing access to immunization ...
. Berkley has appeared on the cover of ''Newsweek'' and recognized by ''Wired'' as among "The Wired 25"—a salute to dreamers, inventors, mavericks and leaders—as well as by ''Time'' magazine as one of the "100 Most Influential People in the World" in 2009. In 2010, ''Fortune'' magazine named Berkley as one of its "Global Forum Visionaries."


Gavi, the Vaccine Alliance

Berkley joined
Gavi, the Vaccine Alliance GAVI, officially Gavi, the Vaccine Alliance (previously the GAVI Alliance, and before that the Global Alliance for Vaccines and Immunization) is a public–private global health partnership with the goal of increasing access to immunization ...
as its chief executive officer (CEO) in August 2011. Gavi is a public-private partnership whose mission is to save children's lives and protect people's health by increasing access to immunisation in developing countries. Since its launch in 2000, Gavi has prevented more than fifteen million future deaths and helped protect 981 million children with new and underused vaccines. Gavi brings together developing country and donor governments, the
World Health Organization The World Health Organization (WHO) is a specialized agency of the United Nations responsible for international public health. The WHO Constitution states its main objective as "the attainment by all peoples of the highest possible level of h ...
,
UNICEF UNICEF (), originally called the United Nations International Children's Emergency Fund in full, now officially United Nations Children's Fund, is an agency of the United Nations responsible for providing Humanitarianism, humanitarian and Devel ...
, the
World Bank The World Bank is an international financial institution that provides loans and grants to the governments of low- and middle-income countries for the purpose of pursuing capital projects. The World Bank is the collective name for the Interna ...
, the vaccine industry in both industrialised and developing countries, research and technical agencies, civil society organizations, the
Bill & Melinda Gates Foundation The Bill & Melinda Gates Foundation (BMGF), a merging of the William H. Gates Foundation and the Gates Learning Foundation, is an American private foundation founded by Bill Gates and Melinda French Gates. Based in Seattle, Washington, it was l ...
and other private philanthropists. Berkley and
Coalition for Epidemic Preparedness Innovations The Coalition for Epidemic Preparedness Innovations (CEPI) is a foundation that takes donations from public, private, philanthropic, and civil society organisations, to finance independent research projects to develop vaccines against emerging ...
(CEPI) CEO Dr.
Richard Hatchett Richard Hatchett is an American oncologist and epidemiologist who has been serving as chief executive officer of the Coalition for Epidemic Preparedness Innovations (CEPI) in Oslo and London since 2017. He was awarded the Secretary of Health and ...
were involved in founding
COVAX COVID-19 Vaccines Global Access, abbreviated as COVAX, is a worldwide initiative aimed at equitable access to COVID-19 vaccines directed by the GAVI vaccine alliance, the Coalition for Epidemic Preparedness Innovations (CEPI), and the World Hea ...
, the global
COVID-19 pandemic The COVID-19 pandemic, also known as the coronavirus pandemic, is an ongoing global pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The novel virus was first identif ...
vaccine initiative, following a meeting at the
World Economic Forum The World Economic Forum (WEF) is an international non-governmental and lobbying organisation based in Cologny, canton of Geneva, Switzerland. It was founded on 24 January 1971 by German engineer and economist Klaus Schwab. The foundation, ...
in
Davos , neighboring_municipalities= Arosa, Bergün/Bravuogn, Klosters-Serneus, Langwies, S-chanf, Susch , twintowns = } Davos (, ; or ; rm, ; archaic it, Tavate) is an Alpine resort town and a municipality in the Prättigau/Davos R ...
br>
COVAX is directed by Gavi, the
Coalition for Epidemic Preparedness Innovations The Coalition for Epidemic Preparedness Innovations (CEPI) is a foundation that takes donations from public, private, philanthropic, and civil society organisations, to finance independent research projects to develop vaccines against emerging ...
(CEPI), the
World Health Organization The World Health Organization (WHO) is a specialized agency of the United Nations responsible for international public health. The WHO Constitution states its main objective as "the attainment by all peoples of the highest possible level of h ...
(WHO) and
UNICEF UNICEF (), originally called the United Nations International Children's Emergency Fund in full, now officially United Nations Children's Fund, is an agency of the United Nations responsible for providing Humanitarianism, humanitarian and Devel ...
.


The IAVI Years

In 1994, the Rockefeller Foundation, where Berkley was serving as associate director of health sciences, convened a series of international consensus meetings on the need for a new effort to address existing barriers to the development of an AIDS vaccine and jump-start AIDS vaccine research. These meetings, culminating in a conference in
Bellagio Bellagio may refer to: * Bellagio, Lombardy, an Italian town * Bellagio (resort), a luxury resort and casino in Las Vegas * Bellagio (Hong Kong), a private housing building * Bellagio declaration, an intellectual copyright resolution * 79271 Bellag ...
, Italy, became the impetus for the establishment of IAVI in 1996 as an international
NGO A non-governmental organization (NGO) or non-governmental organisation (see spelling differences) is an organization that generally is formed independent from government. They are typically nonprofit entities, and many of them are active in h ...
tasked with aggressively pursuing previously neglected approaches to AIDS vaccine development. Berkley was appointed interim president and later became CEO. Under Berkley's leadership, the organization evolved into a worldwide public-private product development partnership with a staff of more than 200 employees that has worked with partners in 25 countries and, with partners, conducted 24 HIV vaccine trials.


Selected professional affiliations

Berkley has sat on a number of international steering committees and corporate and not-for-profit boards, including those of
Gilead Sciences Gilead Sciences, Inc. () is an American biopharmaceutical company headquartered in Foster City, California, that focuses on researching and developing antiviral drugs used in the treatment of HIV/AIDS, hepatitis B, hepatitis C, influenza, and CO ...
, the
New York Academy of Sciences The New York Academy of Sciences (originally the Lyceum of Natural History) was founded in January 1817 as the Lyceum of Natural History. It is the fourth oldest scientific society in the United States. An independent, nonprofit organization wit ...
, the
Acumen Fund Acumen (formerly known as Acumen Fund, legally Acumen Fund, Inc.) is a nonprofit impact investment fund focused on investing in social enterprises that serve low-income individuals in United States. Acumen was founded in April 2001 by Jacquelin ...
, the
Council of Foreign Relations The Council on Foreign Relations (CFR) is an American think tank specializing in U.S. foreign policy and international relations. Founded in 1921, it is a nonprofit organization that is independent and nonpartisan. CFR is based in New York City ...
, the Scientific Advisory Panel assisting the UNAIDS High Level Commission on HIV Prevention,
Oxfam America Oxfam is a British-founded confederation of 21 independent charitable organizations focusing on the alleviation of global poverty, founded in 1942 and led by Oxfam International. History Founded at 17 Broad Street, Oxford, as the Oxford Co ...
, the
Guttmacher Institute The Guttmacher Institute is a research and policy NGO that aims to improve sexual and reproductive health and rights worldwide. This research organization was started in 1968 and works to study, educate, and advance sexual and reproductive health ...
,
VillageReach VillageReach is a registered 501(c)(3) that works with governments to solve health care delivery challenges in low-resource communities. It is headquartered in Seattle, Washington, in the United States, with offices in various countries including ...
, VaxInnate, PowderJect, Napo pharmaceuticals and the US National Academy of Medicine. * Fellow,
American College of Physicians The American College of Physicians (ACP) is a national organization of internists, who specialize in the diagnosis, treatment, and care of adults.Sokanu "What is an Internist?" Retrieved October 20, 2014 With 161,000 members, ACP is the largest ...
Leadership Dialogue: The Rockefeller Foundation and the International AIDS Vaccine Initiative" 2004
/ref> * Fellow,
Council on Foreign Relations The Council on Foreign Relations (CFR) is an American think tank A think tank, or policy institute, is a research institute that performs research and advocacy concerning topics such as social policy, political strategy, economics, mi ...
* Fellow,
Infectious Diseases Society of America The Infectious Diseases Society of America (IDSA) is a medical association representing physicians, scientists and other health care professionals who specialize in infectious diseases. It was founded in 1963 and is based in Arlington, Virginia. ...
* Fellow,
Massachusetts Medical Society The Massachusetts Medical Society (MMS) is the oldest continuously operating state medical association in the United States. Incorporated on November 1, 1781, by an act of the Massachusetts General Court, the MMS is a non-profit organization th ...
* Founding Member, The Network of AIDS Researchers of Eastern and Southern Africa


Academic Appointments

* Adjunct Professor, Brown University School of Medicine * Adjunct Professor,
Columbia University Mailman School of Public Health The Joseph L. Mailman School of Public Health is the public health graduate school of Columbia University. Located on the Columbia University Medical Center campus in the Washington Heights neighborhood of Manhattan, New York City, the school ...
* Adjunct Professor,
New York University School of Medicine NYU Grossman School of Medicine is a medical school of New York University, a private research university in New York City. It was founded in 1841 and is one of two medical schools of the university, with the other being the Long Island School of ...


Selected awards

* 2013,
Nelson Mandela Metropolitan University Nelson Mandela University (formerly known as ''Nelson Mandela Metropolitan University (NMMU)'' ) and before that - the University of Port Elizabeth (UPE), the Port Elizabeth Technikon and Vista University's Port Elizabeth campus. This South Afr ...
, honorary doctorate


Selected works and publications


Books

* * *


Articles

* Berkley SF, Hightower AH, Broome CV, Reingold AL. The relationship of tampon characteristics to menstrual toxic shock syndrome. JAMA 1987; 258:917-920. * The Brazilian Purpuric Fever Study Group (report written by Fleming DW and Berkley SF). Brazilian Purpuric Fever: Epidemic purpura fulminans associated with antecedent purulent conjunctivitis. Lancet 1987; 8562:757-761. * The Brazilian Purpuric Fever Study Group (report written by Berkley SF and Harrison L). Haemophilus aegyptius bacteremia in Brazilian Purpuric Fever. Lancet 1987;8562:761-763. * Berkley SF, Widy-Wirski R, Okware SI, Downing R, Linnan MJ, White KE, Sempala S. Risk factors associated with HIV infection in Uganda. J Infec Dis 1989; 160:22-30. * Berkley SF, Naamara W, Okware SI, Downing R, Konde-lule J, Wawer M, Musagaara M, Musgrave S. AIDS and HIV Infection in women in Uganda—are women more infected than males. AIDS 1990; 4:1237-1242. * Heeler C, Berkley SF. Initial lessons from emerging public-private partnerships in drug and vaccine development. Bulletin of the World Health Organization 2001, 79:728-734. * Klausner RD, Fauci AS, Corey L, Nabel GJ, Gayle H, Berkley S, et al. The Need for a Global HIV Vaccine Enterprise. Science, Jun 27 2003: 2036–2039. * Berkley SF. Thorny issues in the ethics of AIDS vaccine trials. The Lancet, 2003; 362: 992. * Berkley SF. Ending an Epidemic: The International AIDS Vaccine Initiative pioneers a public-private partnership. Innovations, 2006; 1:52-66. * * * * * * *


See also

*
GAVI Alliance GAVI, officially Gavi, the Vaccine Alliance (previously the GAVI Alliance, and before that the Global Alliance for Vaccines and Immunization) is a Public–private partnership, public–private global health partnership with the goal of incr ...
*
International AIDS Vaccine Initiative The International AIDS Vaccine Initiative (IAVI) is a global not-for-profit, public-private partnership working to accelerate the development of vaccines to prevent HIV infection and AIDS. IAVI researches and develops vaccine candidates, conduct ...
*
HIV vaccine An HIV vaccine is a potential vaccine that could be either a preventive vaccine or a therapeutic vaccine, which means it would either protect individuals from being infected with HIV or treat HIV-infected individuals. It is thought that an HIV v ...


References


Further reading


"Where Is The HIV Vaccine?", New York Times, July 2010

"The Renaissance in HIV Vaccine Development – Future Directions", New England Journal of Medicine, July 2010

"HIV and flu - the vaccine strategy." Q&A with Seth Berkley on TED.com


* ttp://www.huffingtonpost.com/dr-seth-berkley Seth Berkley on Huffington Post
"A Shot at Stopping AIDS", Washington Post, December 2007


* ttp://www.ssireview.org/articles/entry/15_minutes_with_seth_berkley/ "15 Minutes with Seth Berkley", Stanford Social Innovation Review, Winter 2004
HIV and flu — the vaccine strategy
(TED2010)
Charlie Rose Interview – July 24, 2007

Charlie Rose Interview – August 7, 2006

The Hunt for an AIDS Vaccine, 2010 Aspen Ideas Festival

Video: Toward a World Without AIDS


External links


Dr. Seth Berkley
at
GAVI GAVI, officially Gavi, the Vaccine Alliance (previously the GAVI Alliance, and before that the Global Alliance for Vaccines and Immunization) is a public–private global health partnership with the goal of increasing access to immunization ...
* * {{DEFAULTSORT:Berkley, Seth 1956 births Living people Alpert Medical School alumni American epidemiologists Harvard Medical School alumni HIV/AIDS researchers American health care chief executives McBurney School alumni Brown University alumni